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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     390
NP_056390                                                              17    2528
NP_001096616                                                           17    2528
NP_001096618                                                           17    2528
NP_001096617                                                           17    2528
NP_001164491                                                           17    4312
NP_689636                                                              17    4312
NP_001157915                                                           17    4312
XP_005262135                                                           17    4312
XP_005262134                                                           17    4312
NP_659440                                                              16    5631
NP_862829                                                              16    5631
NP_848563                                                              16    5631
XP_006723255                                                           16    5631
XP_006723254                                                           16    5631
XP_006723253                                                           16    5631
NP_002007                                                              16    7355
NP_001157207                                                           16    7355
NP_055670                                                              16    7355
XP_006725418                                                           16    7355
XP_006725417                                                           16    7355
XP_006725416                                                           16    7355
XP_006725415                                                           16    7355
XP_006725414                                                           16    7355
XP_005257754                                                           16    7355
XP_005257753                                                           16    7355
XP_006722172                                                           16    7355
XP_006722171                                                           16    7355
XP_006722170                                                           16    7355
NP_005480                                                              15    9605
NP_001239263                                                           15    9605
NP_079434                                                              15    9605
NP_001136004                                                           15    9605
NP_001136005                                                           15    9605
NP_733745                                                              15    9605
NP_001136003                                                           15    9605
NP_001136006                                                           15    9605
NP_114147                                                              15    9605
NP_001035541                                                           15    9605
NP_001035542                                                           15    9605
XP_005260150                                                           15    9605
XP_005251694                                                           15    9605
XP_005251696                                                           15    9605
XP_006714985                                                           15    9605
XP_005266050                                                           15    9605
XP_006714984                                                           15    9605

>NP_004295
          Length = 1620

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LSHNEAARE 9
           L HNEAARE
Sbjct: 366 LPHNEAARE 374



>NP_056390
          Length = 1299

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SHNEAARE 9
           SHNE A+E
Sbjct: 340 SHNEEAKE 347



>NP_001096616
          Length = 1299

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SHNEAARE 9
           SHNE A+E
Sbjct: 340 SHNEEAKE 347



>NP_001096618
          Length = 1293

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SHNEAARE 9
           SHNE A+E
Sbjct: 334 SHNEEAKE 341



>NP_001096617
          Length = 1320

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SHNEAARE 9
           SHNE A+E
Sbjct: 362 SHNEEAKE 369



>NP_001164491
          Length = 696

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   HNEAARE 9
           HNE ARE
Sbjct: 518 HNEDARE 524



>NP_689636
          Length = 696

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   HNEAARE 9
           HNE ARE
Sbjct: 518 HNEDARE 524



>NP_001157915
          Length = 1873

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LSHNEAARE 9
            LSH E +RE
Sbjct: 1316 LSHQERSRE 1324



>XP_005262135
          Length = 696

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   HNEAARE 9
           HNE ARE
Sbjct: 518 HNEDARE 524



>XP_005262134
          Length = 696

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   HNEAARE 9
           HNE ARE
Sbjct: 518 HNEDARE 524



>NP_659440
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SHNEAARE 9
           SH EAAR+
Sbjct: 466 SHAEAARQ 473



>NP_862829
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LSHNEAAR 8
          ++H+EAAR
Sbjct: 42 IAHSEAAR 49



>NP_848563
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSHNEAAR 8
          L H+EAAR
Sbjct: 39 LRHSEAAR 46



>XP_006723255
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LSHNEAAR 8
          ++H+EAAR
Sbjct: 42 IAHSEAAR 49



>XP_006723254
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LSHNEAAR 8
          ++H+EAAR
Sbjct: 42 IAHSEAAR 49



>XP_006723253
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LSHNEAAR 8
          ++H+EAAR
Sbjct: 42 IAHSEAAR 49



>NP_002007
          Length = 4061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SHNEAARE 9
           SH E+AR+
Sbjct: 774 SHQESARD 781




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SHNEAARE 9
            SH E+AR+
Sbjct: 1098 SHQESARD 1105




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SHNEAARE 9
            SH E+AR+
Sbjct: 3367 SHQESARD 3374




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SHNEAARE 9
           SH+E AR+
Sbjct: 495 SHHEQARD 502




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SHNEAARE 9
           SH+E AR+
Sbjct: 820 SHHEQARD 827




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SHNEAARE 9
            SH+E AR+
Sbjct: 1144 SHHEQARD 1151




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SHNEAARE 9
            SH+E AR+
Sbjct: 3413 SHHEQARD 3420



>NP_001157207
          Length = 970

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 516 LGHNKLSRE 524



>NP_055670
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LSHNEAA 7
           LSH EAA
Sbjct: 375 LSHGEAA 381



>XP_006725418
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 251 LGHNKLSRE 259



>XP_006725417
          Length = 725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 271 LGHNKLSRE 279



>XP_006725416
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 354 LGHNKLSRE 362



>XP_006725415
          Length = 990

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 536 LGHNKLSRE 544



>XP_006725414
          Length = 1034

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 580 LGHNKLSRE 588



>XP_005257754
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 251 LGHNKLSRE 259



>XP_005257753
          Length = 707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 253 LGHNKLSRE 261



>XP_006722172
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 354 LGHNKLSRE 362



>XP_006722171
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 518 LGHNKLSRE 526



>XP_006722170
          Length = 1016

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L HN+ +RE
Sbjct: 562 LGHNKLSRE 570



>NP_005480
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 620 LAHLEAAR 627



>NP_001239263
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 709 LAHLEAAR 716



>NP_079434
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L H+E AR+
Sbjct: 505 LQHSERARQ 513



>NP_001136004
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 423 LAHLEAAR 430



>NP_001136005
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 619 LAHLEAAR 626



>NP_733745
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 777 LAHLEAAR 784



>NP_001136003
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 423 LAHLEAAR 430



>NP_001136006
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 617 LAHLEAAR 624



>NP_114147
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LSHNEA 6
           LSHN+A
Sbjct: 231 LSHNQA 236



>NP_001035541
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L H+E AR+
Sbjct: 397 LQHSERARQ 405



>NP_001035542
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L H+E AR+
Sbjct: 397 LQHSERARQ 405



>XP_005260150
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LSHNEA 6
           LSHN+A
Sbjct: 231 LSHNQA 236



>XP_005251694
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 739 LAHLEAAR 746



>XP_005251696
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSHNEAAR 8
           L+H EAAR
Sbjct: 423 LAHLEAAR 430



>XP_006714985
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L H+E AR+
Sbjct: 165 LQHSERARQ 173



>XP_005266050
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L H+E AR+
Sbjct: 262 LQHSERARQ 270



>XP_006714984
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHNEAARE 9
           L H+E AR+
Sbjct: 375 LQHSERARQ 383



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.111    0.282 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 520,413
Number of extensions: 594
Number of successful extensions: 52
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)