Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004360                                                              17    2528
NP_569079                                                              17    2528
NP_064520                                                              17    2528
NP_005179                                                              17    2528
XP_005270205                                                           17    2528
XP_005249289                                                           17    2528
XP_005246122                                                           17    2528
XP_006712316                                                           17    2528
NP_076950                                                              17    2528
NP_055309                                                              17    3301
XP_006721103                                                           17    3301
XP_005255314                                                           17    3301
XP_006721102                                                           17    3301
XP_005255313                                                           17    3301
XP_005255312                                                           17    3301
XP_006721101                                                           17    3301
XP_005255311                                                           17    3301
XP_005255310                                                           17    3301
XP_006713226                                                           17    3301
XP_005265216                                                           17    3301
XP_005265215                                                           17    3301
XP_005265214                                                           17    3301
NP_001018075                                                           16    5631
NP_006171                                                              16    5631
NP_001018074                                                           16    5631
NP_001018076                                                           16    5631
NP_009143                                                              16    5631
NP_001230352                                                           16    5631
XP_005252063                                                           16    5631
XP_006717183                                                           16    5631
XP_005252061                                                           16    5631
XP_005252060                                                           16    5631
XP_005252058                                                           16    5631
XP_005245470                                                           16    5631
XP_005270973                                                           16    5631
XP_005270971                                                           16    5631
XP_005270970                                                           16    5631
NP_000069                                                              16    7355
NP_065194                                                              16    7355
NP_001273014                                                           16    7355
NP_065788                                                              16    7355
NP_114116                                                              16    7355
NP_872292                                                              16    7355
XP_006724188                                                           16    7355
XP_005261382                                                           16    7355
XP_005257087                                                           16    7355
XP_005257086                                                           16    7355
XP_006721187                                                           16    7355
XP_005275864                                                           16    7355
NP_694941                                                              16    7355
NP_006212                                                              15    9605
NP_064592                                                              15    9605
NP_861420                                                              15    9605
NP_005516                                                              15    9605
NP_001193670                                                           15    9605
NP_003639                                                              15    9605
NP_690618                                                              15    9605
NP_001244896                                                           15    9605
NP_057683                                                              15    9605
NP_001244897                                                           15    9605
NP_919276                                                              15    9605
XP_005252384                                                           15    9605
XP_005249718                                                           15    9605
XP_006714297                                                           15    9605
XP_005246167                                                           15    9605
XP_005246165                                                           15    9605
XP_005246164                                                           15    9605
>NP_004360
          Length = 3177

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LSHISNAS 8
           LSHISN S
Sbjct: 103 LSHISNMS 110
>NP_569079
          Length = 640

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           LSH SN+SS
Sbjct: 385 LSHSSNSSS 393
>NP_064520
          Length = 665

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           LSH SN+SS
Sbjct: 410 LSHSSNSSS 418
>NP_005179
          Length = 906

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           LS ISNASS
Sbjct: 790 LSDISNASS 798
>XP_005270205
          Length = 672

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           L+HIS ASS
Sbjct: 501 LAHISGASS 509
>XP_005249289
          Length = 419

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           LSH SN+SS
Sbjct: 410 LSHSSNSSS 418
>XP_005246122
          Length = 2977

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LSHISNAS 8
           LSHISN S
Sbjct: 103 LSHISNMS 110
>XP_006712316
          Length = 3010

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LSHISNAS 8
           LSHISN S
Sbjct: 103 LSHISNMS 110
>NP_076950
          Length = 737

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           L+HIS ASS
Sbjct: 566 LAHISGASS 574
>NP_055309
          Length = 1962

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 504 LSHLSNGES 512
>XP_006721103
          Length = 1597

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 472 LSHLSNGES 480
>XP_005255314
          Length = 1709

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 251 LSHLSNGES 259
>XP_006721102
          Length = 1820

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 362 LSHLSNGES 370
>XP_005255313
          Length = 1822

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 472 LSHLSNGES 480
>XP_005255312
          Length = 1871

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 472 LSHLSNGES 480
>XP_006721101
          Length = 1907

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 472 LSHLSNGES 480
>XP_005255311
          Length = 1913

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 504 LSHLSNGES 512
>XP_005255310
          Length = 1919

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           LSH+SN  S
Sbjct: 472 LSHLSNGES 480
>XP_006713226
          Length = 865

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           L+H SN+SS
Sbjct: 398 LAHFSNSSS 406
>XP_005265216
          Length = 903

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           L+H SN+SS
Sbjct: 398 LAHFSNSSS 406
>XP_005265215
          Length = 906

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           L+H SN+SS
Sbjct: 398 LAHFSNSSS 406
>XP_005265214
          Length = 975

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           L+H SN+SS
Sbjct: 398 LAHFSNSSS 406
>NP_001018075
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 497 LHHISNGSN 505
>NP_006171
          Length = 838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 497 LHHISNGSN 505
>NP_001018074
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 481 LHHISNGSN 489
>NP_001018076
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 481 LHHISNGSN 489
>NP_009143
          Length = 336

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SHISNASS 9
           SH SNAS+
Sbjct: 177 SHCSNAST 184
>NP_001230352
          Length = 70

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  LSHISNASS 9
          ++HISN+S+
Sbjct: 53 VAHISNSST 61
>XP_005252063
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 497 LHHISNGSN 505
>XP_006717183
          Length = 554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 497 LHHISNGSN 505
>XP_005252061
          Length = 838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 497 LHHISNGSN 505
>XP_005252060
          Length = 838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 497 LHHISNGSN 505
>XP_005252058
          Length = 838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L HISN S+
Sbjct: 497 LHHISNGSN 505
>XP_005245470
          Length = 287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SHISNASS 9
           SH SNAS+
Sbjct: 128 SHCSNAST 135
>XP_005270973
          Length = 350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           +SHISN ++
Sbjct: 312 ISHISNTTT 320
>XP_005270971
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           +SHISN ++
Sbjct: 357 ISHISNTTT 365
>XP_005270970
          Length = 420

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           +SHISN ++
Sbjct: 382 ISHISNTTT 390
>NP_000069
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LSHISNASS 9
          +SH+S ASS
Sbjct: 81 ISHLSIASS 89
>NP_065194
          Length = 1819

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    HISNAS 8
            H+SNAS
Sbjct: 1082 HVSNAS 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    HISNAS 8
            H+SNAS
Sbjct: 1109 HVSNAS 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    HISNAS 8
            H+SNAS
Sbjct: 1136 HVSNAS 1141
>NP_001273014
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LSHISNASS 9
          +SH+S ASS
Sbjct: 81 ISHLSIASS 89
>NP_065788
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           L H+SN++S
Sbjct: 379 LPHLSNSTS 387
>NP_114116
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SHISNASS 9
          +H+S+ASS
Sbjct: 69 AHVSSASS 76
>NP_872292
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SHISNASS 9
          +H+S+ASS
Sbjct: 69 AHVSSASS 76
>XP_006724188
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SHISNASS 9
          +H+S+ASS
Sbjct: 50 AHVSSASS 57
>XP_005261382
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SHISNASS 9
          +H+S+ASS
Sbjct: 50 AHVSSASS 57
>XP_005257087
          Length = 957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           ++HIS ASS
Sbjct: 278 IAHISPASS 286
>XP_005257086
          Length = 999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           ++HIS ASS
Sbjct: 320 IAHISPASS 328
>XP_006721187
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LSHISNASS 9
          +SH+S ASS
Sbjct: 81 ISHLSIASS 89
>XP_005275864
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SHISNASS 9
           SHISN  S
Sbjct: 296 SHISNPGS 303
>NP_694941
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSHISNASS 9
           ++HIS ASS
Sbjct: 320 IAHISPASS 328
>NP_006212
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SHISNAS 8
          +HI+NAS
Sbjct: 26 NHITNAS 32
>NP_064592
          Length = 1561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    HISNASS 9
            HI+NA+S
Sbjct: 1257 HITNATS 1263
>NP_861420
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSHISNAS 8
           L+HI+N S
Sbjct: 118 LNHITNTS 125
>NP_005516
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSHISNAS 8
           L+HI+N S
Sbjct: 118 LNHITNTS 125
>NP_001193670
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSHISNAS 8
           L+HI+N S
Sbjct: 118 LNHITNTS 125
>NP_003639
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L+H  NASS
Sbjct: 965 LAHAVNASS 973
>NP_690618
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LSHISNASS 9
            L+H  NASS
Sbjct: 1009 LAHAVNASS 1017
>NP_001244896
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L H++NA S
Sbjct: 218 LDHVTNAFS 226
>NP_057683
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LSHISN 6
          LSH+SN
Sbjct: 47 LSHLSN 52
>NP_001244897
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L H++NA S
Sbjct: 234 LDHVTNAFS 242
>NP_919276
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L H++NA S
Sbjct: 208 LDHVTNAFS 216
>XP_005252384
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   HISNASS 9
           HI+NA+S
Sbjct: 537 HITNATS 543
>XP_005249718
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L H++NA S
Sbjct: 116 LDHVTNAFS 124
>XP_006714297
          Length = 195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LSHISN 6
          LSH+SN
Sbjct: 47 LSHLSN 52
>XP_005246167
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L+H  NASS
Sbjct: 475 LAHAVNASS 483
>XP_005246165
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L+H  NASS
Sbjct: 876 LAHAVNASS 884
>XP_005246164
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSHISNASS 9
           L+H  NASS
Sbjct: 897 LAHAVNASS 905
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.102    0.240 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 544,273
Number of extensions: 770
Number of successful extensions: 69
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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