Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001177203                                                           16    5631
NP_079409                                                              16    5631
NP_000487                                                              16    5631
NP_002842                                                              16    5631
NP_001193767                                                           16    5631
XP_006724204                                                           16    5631
XP_005256679                                                           16    5631
XP_006716139                                                           16    5631
XP_005250576                                                           16    5631
XP_005264631                                                           16    5631
XP_005264630                                                           16    5631
XP_005264629                                                           16    5631
NP_001193768                                                           16    5631
NP_001108446                                                           16    5631
NP_899236                                                              16    7355
NP_001714                                                              16    7355
NP_056363                                                              16    7355
NP_001138241                                                           16    7355
NP_001138242                                                           16    7355
NP_066958                                                              16    7355
NP_001006933                                                           16    7355
NP_001093259                                                           16    7355
NP_001093258                                                           16    7355
NP_001093257                                                           16    7355
NP_000864                                                              16    7355
XP_005267149                                                           16    7355
XP_006715612                                                           16    7355
XP_006715232                                                           16    7355
XP_005249383                                                           16    7355
XP_005249382                                                           16    7355
XP_005249381                                                           16    7355
XP_005249380                                                           16    7355
XP_005249379                                                           16    7355
XP_005249377                                                           16    7355
XP_005249376                                                           16    7355
XP_005249375                                                           16    7355
XP_005249374                                                           16    7355
XP_005249373                                                           16    7355
XP_005249372                                                           16    7355
XP_005249371                                                           16    7355
XP_005249370                                                           16    7355
XP_005249369                                                           16    7355
XP_005249368                                                           16    7355
XP_005249367                                                           16    7355
NP_001093256                                                           16    7355
NP_006845                                                              15    9605
NP_001094073                                                           15    9605
NP_653299                                                              15    9605
NP_057839                                                              15    9605
NP_001267728                                                           15    9605
NP_006846                                                              15    9605
NP_006599                                                              15    9605
NP_002282                                                              15    9605
NP_009077                                                              15    9605
NP_006792                                                              15    9605
NP_075463                                                              15    9605
XP_005257701                                                           15    9605
XP_005257700                                                           15    9605
XP_006719812                                                           15    9605
XP_006710360                                                           15    9605
XP_005270444                                                           15    9605
XP_006710359                                                           15    9605
XP_005270442                                                           15    9605
XP_005270441                                                           15    9605
XP_005270440                                                           15    9605
NP_001004740                                                           15    9605
>NP_001177203
          Length = 927

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SGKSQ L+
Sbjct: 139 VSGKSQDLS 147
>NP_079409
          Length = 843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LSGKSQSLN 9
          +SGKSQ L+
Sbjct: 55 VSGKSQDLS 63
>NP_000487
          Length = 205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SGKSQSLN 9
          +GK QSLN
Sbjct: 9  AGKPQSLN 16
>NP_002842
          Length = 2315

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           LSG ++SLN
Sbjct: 553 LSGTAESLN 561
>NP_001193767
          Length = 1455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           LSG ++SLN
Sbjct: 553 LSGTAESLN 561
>XP_006724204
          Length = 205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SGKSQSLN 9
          +GK QSLN
Sbjct: 9  AGKPQSLN 16
>XP_005256679
          Length = 380

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           LSG+ QSL+
Sbjct: 128 LSGRGQSLD 136
>XP_006716139
          Length = 1869

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           LSG ++SLN
Sbjct: 553 LSGTAESLN 561
>XP_005250576
          Length = 2308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           LSG ++SLN
Sbjct: 553 LSGTAESLN 561
>XP_005264631
          Length = 926

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SGKSQ L+
Sbjct: 139 VSGKSQDLS 147
>XP_005264630
          Length = 953

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SGKSQ L+
Sbjct: 139 VSGKSQDLS 147
>XP_005264629
          Length = 954

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SGKSQ L+
Sbjct: 139 VSGKSQDLS 147
>NP_001193768
          Length = 1448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           LSG ++SLN
Sbjct: 553 LSGTAESLN 561
>NP_001108446
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           LSG+ QSL+
Sbjct: 128 LSGRGQSLD 136
>NP_899236
          Length = 5497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 499 ISGITQSLN 507
>NP_001714
          Length = 2649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 173 ISGITQSLN 181
>NP_056363
          Length = 5171

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 173 ISGITQSLN 181
>NP_001138241
          Length = 5675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 677 ISGITQSLN 685
>NP_001138242
          Length = 5537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 539 ISGITQSLN 547
>NP_066958
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSGKSQSL 8
           LSG++QSL
Sbjct: 282 LSGEAQSL 289
>NP_001006933
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSGKSQSL 8
           LSG++QSL
Sbjct: 290 LSGEAQSL 297
>NP_001093259
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SGKSQSLN 9
           SGK +S+N
Sbjct: 96  SGKQESMN 103
>NP_001093258
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SGKSQSLN 9
           SGK +S+N
Sbjct: 96  SGKQESMN 103
>NP_001093257
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SGKSQSLN 9
           SGK +S+N
Sbjct: 96  SGKQESMN 103
>NP_000864
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SGKSQSLN 9
           SGK +S+N
Sbjct: 96  SGKQESMN 103
>XP_005267149
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSGKSQSL 8
           LSG++QSL
Sbjct: 307 LSGEAQSL 314
>XP_006715612
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSGKSQSL 8
           LSG++QSL
Sbjct: 310 LSGEAQSL 317
>XP_006715232
          Length = 7498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 499 ISGITQSLN 507
>XP_005249383
          Length = 3186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 710 ISGITQSLN 718
>XP_005249382
          Length = 5732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 710 ISGITQSLN 718
>XP_005249381
          Length = 7281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 173 ISGITQSLN 181
>XP_005249380
          Length = 7607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 499 ISGITQSLN 507
>XP_005249379
          Length = 7633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 525 ISGITQSLN 533
>XP_005249377
          Length = 7640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 532 ISGITQSLN 540
>XP_005249376
          Length = 7647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 539 ISGITQSLN 547
>XP_005249375
          Length = 7680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 572 ISGITQSLN 580
>XP_005249374
          Length = 7709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 710 ISGITQSLN 718
>XP_005249373
          Length = 7723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 615 ISGITQSLN 623
>XP_005249372
          Length = 7785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 677 ISGITQSLN 685
>XP_005249371
          Length = 7788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 710 ISGITQSLN 718
>XP_005249370
          Length = 7794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 710 ISGITQSLN 718
>XP_005249369
          Length = 7797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 689 ISGITQSLN 697
>XP_005249368
          Length = 7812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 710 ISGITQSLN 718
>XP_005249367
          Length = 7818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG +QSLN
Sbjct: 710 ISGITQSLN 718
>NP_001093256
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SGKSQSLN 9
           SGK +S+N
Sbjct: 96  SGKQESMN 103
>NP_006845
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSGKSQSL 8
          +SGKSQ L
Sbjct: 32 ISGKSQLL 39
>NP_001094073
          Length = 186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSGKSQSL 8
          +SGKSQ L
Sbjct: 32 ISGKSQLL 39
>NP_653299
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSGKSQSL 8
           +SGKSQ +
Sbjct: 800 MSGKSQEI 807
>NP_057839
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSGKSQSL 8
          +SGKSQ L
Sbjct: 32 ISGKSQIL 39
>NP_001267728
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSGKSQSL 8
           +SGKSQ +
Sbjct: 710 MSGKSQEI 717
>NP_006846
          Length = 214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSGKSQSL 8
          +SGKSQ L
Sbjct: 32 ISGKSQIL 39
>NP_006599
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG S+SLN
Sbjct: 355 VSGGSRSLN 363
>NP_002282
          Length = 1786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LSGKSQSLN 9
            L+GK QSL+
Sbjct: 1381 LAGKLQSLD 1389
>NP_009077
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GKSQSLN 9
           G+SQS+N
Sbjct: 309 GQSQSIN 315
>NP_006792
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSGKSQSL 8
          +SGKSQ L
Sbjct: 32 ISGKSQVL 39
>NP_075463
          Length = 3013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LSGKSQSLN 9
            LSG + SLN
Sbjct: 2504 LSGSTPSLN 2512
>XP_005257701
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GKSQSLN 9
           G+SQS+N
Sbjct: 306 GQSQSIN 312
>XP_005257700
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GKSQSLN 9
           G+SQS+N
Sbjct: 315 GQSQSIN 321
>XP_006719812
          Length = 3019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LSGKSQSLN 9
            LSG + SLN
Sbjct: 2504 LSGSTPSLN 2512
>XP_006710360
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG S+SLN
Sbjct: 355 VSGGSRSLN 363
>XP_005270444
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG S+SLN
Sbjct: 355 VSGGSRSLN 363
>XP_006710359
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG S+SLN
Sbjct: 313 VSGGSRSLN 321
>XP_005270442
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG S+SLN
Sbjct: 326 VSGGSRSLN 334
>XP_005270441
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG S+SLN
Sbjct: 355 VSGGSRSLN 363
>XP_005270440
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSGKSQSLN 9
           +SG S+SLN
Sbjct: 355 VSGGSRSLN 363
>NP_001004740
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LSGKSQSL 8
           LSG SQSL
Sbjct: 154 LSGFSQSL 161
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.290    0.110    0.257 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 521,028
Number of extensions: 719
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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