Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006056                                                              19     869
XP_005260701                                                           19     869
XP_005260700                                                           19     869
XP_005260698                                                           19     869
XP_006710313                                                           19     869
NP_001077379                                                           19     869
NP_079133                                                              18    1482
NP_055632                                                              17    4312
NP_003371                                                              16    5631
NP_001116325                                                           16    5631
NP_056011                                                              16    5631
NP_001124479                                                           16    5631
NP_588612                                                              16    5631
XP_006717563                                                           16    5631
XP_005262928                                                           16    5631
XP_005262927                                                           16    5631
XP_005262926                                                           16    5631
NP_001231118                                                           16    7355
NP_001231121                                                           16    7355
NP_055564                                                              16    7355
NP_001231119                                                           16    7355
NP_001231120                                                           16    7355
NP_001231122                                                           16    7355
NP_079082                                                              16    7355
NP_851825                                                              16    7355
NP_001229347                                                           16    7355
NP_001229346                                                           16    7355
NP_001229345                                                           16    7355
NP_653175                                                              16    7355
NP_851808                                                              16    7355
XP_006720406                                                           16    7355
XP_006720405                                                           16    7355
XP_006720404                                                           16    7355
XP_006720403                                                           16    7355
XP_006720402                                                           16    7355
XP_006720401                                                           16    7355
XP_006720400                                                           16    7355
XP_006720399                                                           16    7355
XP_006720376                                                           16    7355
XP_006720375                                                           16    7355
XP_006720374                                                           16    7355
XP_006720373                                                           16    7355
XP_006720372                                                           16    7355
XP_006720371                                                           16    7355
XP_006720370                                                           16    7355
XP_006720369                                                           16    7355
XP_005271738                                                           16    7355
XP_006718978                                                           16    7355
XP_005271736                                                           16    7355
XP_005271737                                                           16    7355
NP_570124                                                              15    9605
NP_000634                                                              15    9605
NP_000635                                                              15    9605
NP_000636                                                              15    9605
NP_000019                                                              15    9605
NP_000637                                                              15    9605
NP_000633                                                              15    9605
NP_004085                                                              15    9605
NP_055887                                                              15    9605
NP_694962                                                              15    9605
NP_073613                                                              15    9605
NP_001157918                                                           15    9605
XP_006715913                                                           15    9605
XP_005270614                                                           15    9605
NP_060918                                                              15    9605
>NP_006056
          Length = 398

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LSELSKRNN 9
           +SEL+KRNN
Sbjct: 92  VSELTKRNN 100
>XP_005260701
          Length = 180

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1  LSELSKRNN 9
          +SEL+KRNN
Sbjct: 91 VSELTKRNN 99
>XP_005260700
          Length = 286

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1  LSELSKRNN 9
          +SEL+KRNN
Sbjct: 91 VSELTKRNN 99
>XP_005260698
          Length = 397

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1  LSELSKRNN 9
          +SEL+KRNN
Sbjct: 91 VSELTKRNN 99
>XP_006710313
          Length = 160

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1  LSELSKRNN 9
          +SEL+KRNN
Sbjct: 75 VSELTKRNN 83
>NP_001077379
          Length = 181

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LSELSKRNN 9
           +SEL+KRNN
Sbjct: 92  VSELTKRNN 100
>NP_079133
          Length = 1844

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    ELSKRNN 9
            ELSKRNN
Sbjct: 1029 ELSKRNN 1035
>NP_055632
          Length = 811

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSELSKRNN 9
           L ELS RNN
Sbjct: 327 LRELSLRNN 335
>NP_003371
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSELSKRNN 9
           LSE + RNN
Sbjct: 298 LSEAANRNN 306
>NP_001116325
          Length = 251

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSELSKRNN 9
          + ELS RNN
Sbjct: 38 MEELSLRNN 46
>NP_056011
          Length = 1609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LSELSKRNN 9
            L E+S++NN
Sbjct: 1130 LPEISRKNN 1138
>NP_001124479
          Length = 1610

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LSELSKRNN 9
            L E+S++NN
Sbjct: 1131 LPEISRKNN 1139
>NP_588612
          Length = 251

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSELSKRNN 9
          + ELS RNN
Sbjct: 38 MEELSLRNN 46
>XP_006717563
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSELSKRNN 9
           LSE + RNN
Sbjct: 298 LSEAANRNN 306
>XP_005262928
          Length = 965

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSELSKRNN 9
           L E+S++NN
Sbjct: 486 LPEISRKNN 494
>XP_005262927
          Length = 1526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LSELSKRNN 9
            L E+S++NN
Sbjct: 1047 LPEISRKNN 1055
>XP_005262926
          Length = 1609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LSELSKRNN 9
            L E+S++NN
Sbjct: 1131 LPEISRKNN 1139
>NP_001231118
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 409 ELSKREN 415
>NP_001231121
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 312 ELSKREN 318
>NP_055564
          Length = 1472

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>NP_001231119
          Length = 1533

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 341 ELSKREN 347
>NP_001231120
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 271 ELSKREN 277
>NP_001231122
          Length = 1347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 216 ELSKREN 222
>NP_079082
          Length = 778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSELSKRN 8
           L+ELSKR+
Sbjct: 496 LNELSKRH 503
>NP_851825
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 289 SRLSKRNS 296
>NP_001229347
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 362 SRLSKRNS 369
>NP_001229346
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 381 SRLSKRNS 388
>NP_001229345
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 289 SRLSKRNS 296
>NP_653175
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 350 SRLSKRNS 357
>NP_851808
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 350 SRLSKRNS 357
>XP_006720406
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720405
          Length = 1347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720404
          Length = 1477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720403
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720402
          Length = 1487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720401
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720400
          Length = 1526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720399
          Length = 1548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELSKRNN 9
           ELSKR N
Sbjct: 356 ELSKREN 362
>XP_006720376
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 93  SRLSKRNS 100
>XP_006720375
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 93  SRLSKRNS 100
>XP_006720374
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 177 SRLSKRNS 184
>XP_006720373
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 177 SRLSKRNS 184
>XP_006720372
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 177 SRLSKRNS 184
>XP_006720371
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 289 SRLSKRNS 296
>XP_006720370
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 350 SRLSKRNS 357
>XP_006720369
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S LSKRN+
Sbjct: 350 SRLSKRNS 357
>XP_005271738
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSELSKRN 8
           L+ELSKR+
Sbjct: 496 LNELSKRH 503
>XP_006718978
          Length = 740

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSELSKRN 8
           L+ELSKR+
Sbjct: 458 LNELSKRH 465
>XP_005271736
          Length = 778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSELSKRN 8
           L+ELSKR+
Sbjct: 496 LNELSKRH 503
>XP_005271737
          Length = 778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LSELSKRN 8
           L+ELSKR+
Sbjct: 496 LNELSKRH 503
>NP_570124
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SELSKRN 8
           SE++KRN
Sbjct: 219 SEIAKRN 225
>NP_000634
          Length = 1532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSELSKRN 8
            L ELSK+N
Sbjct: 1297 LLELSKKN 1304
>NP_000635
          Length = 1532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSELSKRN 8
            L ELSK+N
Sbjct: 1297 LLELSKKN 1304
>NP_000636
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSELSKRN 8
            L ELSK+N
Sbjct: 1280 LLELSKKN 1287
>NP_000019
          Length = 1532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSELSKRN 8
            L ELSK+N
Sbjct: 1297 LLELSKKN 1304
>NP_000637
          Length = 1516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSELSKRN 8
            L ELSK+N
Sbjct: 1281 LLELSKKN 1288
>NP_000633
          Length = 1532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSELSKRN 8
            L ELSK+N
Sbjct: 1297 LLELSKKN 1304
>NP_004085
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LSELSKR 7
          LSELS+R
Sbjct: 48 LSELSRR 54
>NP_055887
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SELSKRNN 9
           S++SK NN
Sbjct: 822 SKISKNNN 829
>NP_694962
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSELSKRNN 9
           LS LSK NN
Sbjct: 116 LSCLSKSNN 124
>NP_073613
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LSELSKRNN 9
           L  LSKR N
Sbjct: 203 LQSLSKRTN 211
>NP_001157918
          Length = 1188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SELSKRNN 9
           +ELS+R+N
Sbjct: 927 TELSRRHN 934
>XP_006715913
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  SELSKRN 8
          SE++KRN
Sbjct: 11 SEIAKRN 17
>XP_005270614
          Length = 1532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSELSKRN 8
            L ELSK+N
Sbjct: 1297 LLELSKKN 1304
>NP_060918
          Length = 1230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSELSKRNN 9
           LSELSK ++
Sbjct: 219 LSELSKNDS 227
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.114    0.265 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 422,482
Number of extensions: 563
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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