Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     390
NP_001075109                                                           20     390
NP_689540                                                              18    1935
XP_006720086                                                           18    1935
XP_006720085                                                           18    1935
XP_006720084                                                           18    1935
NP_000916                                                              17    2528
NP_001166939                                                           17    2528
NP_001258973                                                           17    3301
NP_001258989                                                           17    3301
NP_003152                                                              17    3301
NP_001258972                                                           17    3301
NP_001258971                                                           17    3301
NP_003943                                                              17    3301
XP_006722072                                                           17    3301
XP_006718720                                                           17    3301
XP_006718719                                                           17    3301
XP_005274222                                                           17    3301
XP_006718718                                                           17    3301
XP_005274221                                                           17    3301
NP_002636                                                              17    4312
XP_005253036                                                           17    4312
XP_005253035                                                           17    4312
XP_005253034                                                           17    4312
NP_004295                                                              16    7355
NP_113602                                                              16    7355
NP_001247434                                                           16    7355
NP_116562                                                              16    7355
NP_001247433                                                           16    7355
NP_001009959                                                           16    7355
NP_065762                                                              16    7355
NP_001189                                                              16    7355
NP_878911                                                              16    7355
XP_006715821                                                           16    7355
XP_005249868                                                           16    7355
XP_005267151                                                           16    7355
XP_006715613                                                           16    7355
XP_001717126                                                           16    7355
NP_899236                                                              15    9605
NP_056363                                                              15    9605
NP_001138241                                                           15    9605
NP_001138242                                                           15    9605
NP_056390                                                              15    9605
NP_001096616                                                           15    9605
NP_001096618                                                           15    9605
NP_001096617                                                           15    9605
NP_112494                                                              15    9605
NP_004704                                                              15    9605
NP_064569                                                              15    9605
XP_005268258                                                           15    9605
XP_005268257                                                           15    9605
XP_005268256                                                           15    9605
XP_006715232                                                           15    9605
XP_005249382                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
XP_005263972                                                           15    9605
XP_005263971                                                           15    9605
NP_001139669                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSEEVSQFD 9
            LSEE+SQFD
Sbjct: 2036 LSEEMSQFD 2044
>NP_001075109
          Length = 4097

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSEEVSQFD 9
            LSEE+SQFD
Sbjct: 2036 LSEEMSQFD 2044
>NP_689540
          Length = 723

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSEEVSQFD 9
           LSEEVS F+
Sbjct: 136 LSEEVSHFE 144
>XP_006720086
          Length = 703

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSEEVSQFD 9
           LSEEVS F+
Sbjct: 136 LSEEVSHFE 144
>XP_006720085
          Length = 704

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSEEVSQFD 9
           LSEEVS F+
Sbjct: 136 LSEEVSHFE 144
>XP_006720084
          Length = 730

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSEEVSQFD 9
           LSEEVS F+
Sbjct: 136 LSEEVSHFE 144
>NP_000916
          Length = 359

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LSEEVSQFD 9
          L EEV+Q+D
Sbjct: 56 LGEEVAQYD 64
>NP_001166939
          Length = 341

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LSEEVSQFD 9
          L EEV+Q+D
Sbjct: 56 LGEEVAQYD 64
>NP_001258973
          Length = 472

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 324 EDVSQFD 330
>NP_001258989
          Length = 502

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 354 EDVSQFD 360
>NP_003152
          Length = 525

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 377 EDVSQFD 383
>NP_001258972
          Length = 451

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 377 EDVSQFD 383
>NP_001258971
          Length = 502

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 354 EDVSQFD 360
>NP_003943
          Length = 482

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 353 EDVSQFD 359
>XP_006722072
          Length = 322

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 174 EDVSQFD 180
>XP_006718720
          Length = 282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 153 EDVSQFD 159
>XP_006718719
          Length = 282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 153 EDVSQFD 159
>XP_005274222
          Length = 282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 153 EDVSQFD 159
>XP_006718718
          Length = 282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 153 EDVSQFD 159
>XP_005274221
          Length = 385

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           E+VSQFD
Sbjct: 256 EDVSQFD 262
>NP_002636
          Length = 1686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SEEVSQFD 9
           SE++S+FD
Sbjct: 262 SEDISKFD 269
>XP_005253036
          Length = 1686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SEEVSQFD 9
           SE++S+FD
Sbjct: 262 SEDISKFD 269
>XP_005253035
          Length = 1686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SEEVSQFD 9
           SE++S+FD
Sbjct: 262 SEDISKFD 269
>XP_005253034
          Length = 1686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SEEVSQFD 9
           SE++S+FD
Sbjct: 262 SEDISKFD 269
>NP_004295
          Length = 1620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SEEVSQFD 9
           SEE SQ D
Sbjct: 295 SEEASQMD 302
>NP_113602
          Length = 1019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           +EV+QFD
Sbjct: 154 QEVTQFD 160
>NP_001247434
          Length = 996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           +EV+QFD
Sbjct: 154 QEVTQFD 160
>NP_116562
          Length = 996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           +EV+QFD
Sbjct: 131 QEVTQFD 137
>NP_001247433
          Length = 996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           +EV+QFD
Sbjct: 131 QEVTQFD 137
>NP_001009959
          Length = 297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EEVSQF 8
           EEVSQF
Sbjct: 224 EEVSQF 229
>NP_065762
          Length = 284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EEVSQF 8
           EEVSQF
Sbjct: 211 EEVSQF 216
>NP_001189
          Length = 825

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LSEEVSQFD 9
           ++EE+ +FD
Sbjct: 726 INEEIEKFD 734
>NP_878911
          Length = 691

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LSEEVSQFD 9
           ++EE+ +FD
Sbjct: 592 INEEIEKFD 600
>XP_006715821
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           +EV+QFD
Sbjct: 154 QEVTQFD 160
>XP_005249868
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EEVSQFD 9
           +EV+QFD
Sbjct: 154 QEVTQFD 160
>XP_005267151
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LSEEVSQFD 9
           ++EE+ +FD
Sbjct: 568 INEEIEKFD 576
>XP_006715613
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LSEEVSQFD 9
           ++EE+ +FD
Sbjct: 697 INEEIEKFD 705
>XP_001717126
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SEEVSQFD 9
           SE++S+FD
Sbjct: 539 SEDLSRFD 546
>NP_899236
          Length = 5497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 1835 LQEELEKFD 1843
>NP_056363
          Length = 5171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 1509 LQEELEKFD 1517
>NP_001138241
          Length = 5675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 2013 LQEELEKFD 2021
>NP_001138242
          Length = 5537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 1875 LQEELEKFD 1883
>NP_056390
          Length = 1299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEEVSQFD 9
           S+E SQF+
Sbjct: 388 SQEASQFE 395
>NP_001096616
          Length = 1299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEEVSQFD 9
           S+E SQF+
Sbjct: 388 SQEASQFE 395
>NP_001096618
          Length = 1293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEEVSQFD 9
           S+E SQF+
Sbjct: 382 SQEASQFE 389
>NP_001096617
          Length = 1320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SEEVSQFD 9
           S+E SQF+
Sbjct: 409 SQEASQFE 416
>NP_112494
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EEVSQFD 9
           EE+ QFD
Sbjct: 500 EELKQFD 506
>NP_004704
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSEEVSQFD 9
           +SEE+ Q D
Sbjct: 691 ISEEMEQLD 699
>NP_064569
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSEEVSQF 8
           L+ EVSQF
Sbjct: 558 LATEVSQF 565
>XP_005268258
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSEEVSQFD 9
           +SEE+ Q D
Sbjct: 462 ISEEMEQLD 470
>XP_005268257
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSEEVSQFD 9
           +SEE+ Q D
Sbjct: 477 ISEEMEQLD 485
>XP_005268256
          Length = 1055

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSEEVSQFD 9
           +SEE+ Q D
Sbjct: 670 ISEEMEQLD 678
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 3921 LQEELEKFD 3929
>XP_005249382
          Length = 5732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 2046 LQEELEKFD 2054
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 3595 LQEELEKFD 3603
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 3921 LQEELEKFD 3929
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 3947 LQEELEKFD 3955
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 3954 LQEELEKFD 3962
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 3961 LQEELEKFD 3969
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 3994 LQEELEKFD 4002
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 4132 LQEELEKFD 4140
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 4037 LQEELEKFD 4045
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 4099 LQEELEKFD 4107
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 4132 LQEELEKFD 4140
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 4132 LQEELEKFD 4140
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 4111 LQEELEKFD 4119
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 4132 LQEELEKFD 4140
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LSEEVSQFD 9
            L EE+ +FD
Sbjct: 4132 LQEELEKFD 4140
>XP_005263972
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSEEVSQF 8
           L+ EVSQF
Sbjct: 558 LATEVSQF 565
>XP_005263971
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSEEVSQF 8
           L+ EVSQF
Sbjct: 558 LATEVSQF 565
>NP_001139669
          Length = 7081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    LSEEVSQF 8
            +SE++SQ+
Sbjct: 2925 ISEDISQY 2932
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.122    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 480,818
Number of extensions: 1149
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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