Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005179                                                              18    1935
NP_004851                                                              16    5631
NP_060959                                                              16    5631
XP_005245394                                                           16    5631
XP_005245393                                                           16    5631
XP_006711515                                                           16    5631
XP_006711514                                                           16    5631
XP_006711513                                                           16    5631
NP_149038                                                              16    7355
NP_004662                                                              15    9605
NP_775298                                                              15    9605
NP_733793                                                              15    9605
NP_004832                                                              15    9605
NP_055919                                                              15    9605
NP_006763                                                              15    9605
XP_006722636                                                           15    9605
XP_005258440                                                           15    9605
XP_005258439                                                           15    9605
XP_005258438                                                           15    9605
XP_005258436                                                           15    9605
XP_005258434                                                           15    9605
XP_006722635                                                           15    9605
XP_006722634                                                           15    9605
XP_005273907                                                           15    9605
XP_005273906                                                           15    9605
XP_005245679                                                           15    9605
XP_005245678                                                           15    9605
XP_005245677                                                           15    9605
XP_006711697                                                           15    9605
>NP_005179
          Length = 906

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LSDISTASS 9
           LSDIS ASS
Sbjct: 790 LSDISNASS 798
>NP_004851
          Length = 673

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SDISTAS 8
           SD+STAS
Sbjct: 447 SDVSTAS 453
>NP_060959
          Length = 2964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDISTASS 9
           SD+STA S
Sbjct: 538 SDVSTAKS 545
>XP_005245394
          Length = 1741

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDISTASS 9
           SD+STA S
Sbjct: 538 SDVSTAKS 545
>XP_005245393
          Length = 2663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDISTASS 9
           SD+STA S
Sbjct: 538 SDVSTAKS 545
>XP_006711515
          Length = 2904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDISTASS 9
           SD+STA S
Sbjct: 538 SDVSTAKS 545
>XP_006711514
          Length = 2964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDISTASS 9
           SD+STA S
Sbjct: 538 SDVSTAKS 545
>XP_006711513
          Length = 2964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDISTASS 9
           SD+STA S
Sbjct: 538 SDVSTAKS 545
>NP_149038
          Length = 512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SDISTASS 9
           SDI TASS
Sbjct: 118 SDIITASS 125
>NP_004662
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSDISTASS 9
          LSD+ST  S
Sbjct: 72 LSDLSTIKS 80
>NP_775298
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSDISTASS 9
          LSD+ST  S
Sbjct: 72 LSDLSTIKS 80
>NP_733793
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSDISTASS 9
           L ++STASS
Sbjct: 945 LENLSTASS 953
>NP_004832
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSDISTASS 9
           L ++STASS
Sbjct: 804 LENLSTASS 812
>NP_055919
          Length = 1938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSDISTASS 9
           LSD+  ASS
Sbjct: 384 LSDVDLASS 392
>NP_006763
          Length = 1343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LSDISTA 7
           L+DISTA
Sbjct: 718 LNDISTA 724
>XP_006722636
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSDISTASS 9
           LSD+ST  S
Sbjct: 111 LSDLSTIKS 119
>XP_005258440
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSDISTASS 9
          LSD+ST  S
Sbjct: 63 LSDLSTIKS 71
>XP_005258439
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSDISTASS 9
          LSD+ST  S
Sbjct: 63 LSDLSTIKS 71
>XP_005258438
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSDISTASS 9
          LSD+ST  S
Sbjct: 63 LSDLSTIKS 71
>XP_005258436
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSDISTASS 9
          LSD+ST  S
Sbjct: 72 LSDLSTIKS 80
>XP_005258434
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSDISTASS 9
          LSD+ST  S
Sbjct: 76 LSDLSTIKS 84
>XP_006722635
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSDISTASS 9
           LSD+ST  S
Sbjct: 111 LSDLSTIKS 119
>XP_006722634
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSDISTASS 9
           LSD+ST  S
Sbjct: 111 LSDLSTIKS 119
>XP_005273907
          Length = 1930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSDISTASS 9
           LSD+  ASS
Sbjct: 384 LSDVDLASS 392
>XP_005273906
          Length = 1932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSDISTASS 9
           LSD+  ASS
Sbjct: 384 LSDVDLASS 392
>XP_005245679
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSDISTASS 9
           L ++STASS
Sbjct: 804 LENLSTASS 812
>XP_005245678
          Length = 1145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSDISTASS 9
           L ++STASS
Sbjct: 807 LENLSTASS 815
>XP_005245677
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSDISTASS 9
           L ++STASS
Sbjct: 835 LENLSTASS 843
>XP_006711697
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSDISTASS 9
           L ++STASS
Sbjct: 844 LENLSTASS 852
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286   0.0990    0.210 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 301,533
Number of extensions: 305
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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