Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1135
XP_006716142                                                           18    1135
XP_005250088                                                           18    1135
XP_006716141                                                           18    1135
XP_005250085                                                           18    1135
XP_006716140                                                           18    1135
XP_005250084                                                           18    1135
XP_005250083                                                           18    1135
XP_005250082                                                           18    1135
NP_003473                                                              17    4312
XP_006719679                                                           17    4312
XP_005269219                                                           17    4312
XP_006719678                                                           17    4312
XP_006719677                                                           17    4312
NP_937825                                                              16    5631
NP_008913                                                              16    5631
NP_079191                                                              16    5631
NP_872393                                                              16    5631
XP_005269222                                                           16    5631
XP_006712515                                                           16    5631
XP_006712513                                                           16    5631
XP_006712512                                                           16    5631
XP_006712511                                                           16    5631
XP_006712510                                                           16    5631
XP_006712509                                                           16    5631
XP_005246533                                                           16    5631
XP_006712508                                                           16    5631
XP_005246216                                                           16    5631
XP_006711947                                                           16    5631
XP_005246215                                                           16    5631
XP_006711946                                                           16    5631
XP_006711945                                                           16    5631
NP_115893                                                              16    5631
NP_001138679                                                           16    7355
NP_671725                                                              16    7355
NP_757379                                                              16    7355
NP_001171922                                                           16    7355
NP_001274730                                                           16    7355
XP_006719916                                                           16    7355
XP_006719915                                                           16    7355
XP_006719914                                                           16    7355
XP_005266530                                                           16    7355
XP_006719913                                                           16    7355
XP_006719912                                                           16    7355
XP_006719911                                                           16    7355
XP_006719910                                                           16    7355
XP_006719909                                                           16    7355
XP_006710418                                                           16    7355
NP_112567                                                              16    7355
NP_000526                                                              15    9605
NP_665698                                                              15    9605
NP_620689                                                              15    9605
NP_612504                                                              15    9605
NP_065776                                                              15    9605
XP_006715966                                                           15    9605
XP_005250277                                                           15    9605
XP_006715965                                                           15    9605
XP_005250276                                                           15    9605
XP_006715964                                                           15    9605
XP_006715963                                                           15    9605
XP_006715806                                                           15    9605
XP_006715805                                                           15    9605
XP_006713075                                                           15    9605
XP_005264983                                                           15    9605
XP_005264981                                                           15    9605
XP_005264980                                                           15    9605
XP_006713074                                                           15    9605
XP_005264979                                                           15    9605
XP_005264978                                                           15    9605
XP_006711326                                                           15    9605
XP_005273145                                                           15    9605
XP_006711325                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3212 LSAKQRTAK 3220
>XP_006716142
          Length = 4927

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3229 LSAKQRTAK 3237
>XP_005250088
          Length = 4928

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3229 LSAKQRTAK 3237
>XP_006716141
          Length = 4959

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3229 LSAKQRTAK 3237
>XP_005250085
          Length = 4979

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3229 LSAKQRTAK 3237
>XP_006716140
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3229 LSAKQRTAK 3237
>XP_005250084
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3229 LSAKQRTAK 3237
>XP_005250083
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3228 LSAKQRTAK 3236
>XP_005250082
          Length = 4983

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSAKQHTAK 9
            LSAKQ TAK
Sbjct: 3229 LSAKQRTAK 3237
>NP_003473
          Length = 5537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LSAKQHTAK 9
            L AKQ TAK
Sbjct: 3542 LCAKQRTAK 3550
>XP_006719679
          Length = 5536

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LSAKQHTAK 9
            L AKQ TAK
Sbjct: 3541 LCAKQRTAK 3549
>XP_005269219
          Length = 5537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LSAKQHTAK 9
            L AKQ TAK
Sbjct: 3542 LCAKQRTAK 3550
>XP_006719678
          Length = 5539

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LSAKQHTAK 9
            L AKQ TAK
Sbjct: 3544 LCAKQRTAK 3552
>XP_006719677
          Length = 5540

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LSAKQHTAK 9
            L AKQ TAK
Sbjct: 3545 LCAKQRTAK 3553
>NP_937825
          Length = 618

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AKQHTAK 9
           ++QHTAK
Sbjct: 326 SRQHTAK 332
>NP_008913
          Length = 326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSAKQHTA 8
           + AK+HTA
Sbjct: 313 MKAKEHTA 320
>NP_079191
          Length = 625

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AKQHTAK 9
           ++QHTAK
Sbjct: 322 SRQHTAK 328
>NP_872393
          Length = 3234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2865 LSARQHIA 2872
>XP_005269222
          Length = 326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSAKQHTA 8
           + AK+HTA
Sbjct: 313 MKAKEHTA 320
>XP_006712515
          Length = 3232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2863 LSARQHIA 2870
>XP_006712513
          Length = 3220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2832 LSARQHIA 2839
>XP_006712512
          Length = 3237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2868 LSARQHIA 2875
>XP_006712511
          Length = 3256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2868 LSARQHIA 2875
>XP_006712510
          Length = 3305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2936 LSARQHIA 2943
>XP_006712509
          Length = 3319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2931 LSARQHIA 2938
>XP_005246533
          Length = 3323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2935 LSARQHIA 2942
>XP_006712508
          Length = 3324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2936 LSARQHIA 2943
>XP_005246216
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AKQHTAK 9
           ++QHTAK
Sbjct: 137 SRQHTAK 143
>XP_006711947
          Length = 441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AKQHTAK 9
           ++QHTAK
Sbjct: 137 SRQHTAK 143
>XP_005246215
          Length = 467

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AKQHTAK 9
           ++QHTAK
Sbjct: 175 SRQHTAK 181
>XP_006711946
          Length = 580

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AKQHTAK 9
           ++QHTAK
Sbjct: 326 SRQHTAK 332
>XP_006711945
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AKQHTAK 9
           ++QHTAK
Sbjct: 326 SRQHTAK 332
>NP_115893
          Length = 3258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSAKQHTA 8
            LSA+QH A
Sbjct: 2870 LSARQHIA 2877
>NP_001138679
          Length = 632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           SAK HT K
Sbjct: 355 SAKNHTFK 362
>NP_671725
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LSAKQHTA 8
           L AKQH A
Sbjct: 366 LRAKQHAA 373
>NP_757379
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LSAKQHTA 8
           L AKQH A
Sbjct: 361 LRAKQHAA 368
>NP_001171922
          Length = 1619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 541 SAKQHIA 547
>NP_001274730
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSAKQHTA 8
           +SAK HT+
Sbjct: 257 ISAKDHTS 264
>XP_006719916
          Length = 1482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 400 SAKQHIA 406
>XP_006719915
          Length = 1531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 400 SAKQHIA 406
>XP_006719914
          Length = 1639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 561 SAKQHIA 567
>XP_005266530
          Length = 1643

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 561 SAKQHIA 567
>XP_006719913
          Length = 1650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 561 SAKQHIA 567
>XP_006719912
          Length = 1672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 541 SAKQHIA 547
>XP_006719911
          Length = 1688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 561 SAKQHIA 567
>XP_006719910
          Length = 1692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 561 SAKQHIA 567
>XP_006719909
          Length = 1692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 561 SAKQHIA 567
>XP_006710418
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LSAKQHTA 8
           L AKQH A
Sbjct: 361 LRAKQHAA 368
>NP_112567
          Length = 1623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SAKQHTA 8
           SAKQH A
Sbjct: 541 SAKQHIA 547
>NP_000526
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LSAKQHTAK 9
          L+ K HT+K
Sbjct: 83 LTLKHHTSK 91
>NP_665698
          Length = 1320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           S K HTAK
Sbjct: 157 SDKPHTAK 164
>NP_620689
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSAKQHTAK 9
           L AK+H A+
Sbjct: 537 LKAKEHAAQ 545
>NP_612504
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  SAKQHT 7
          S+KQHT
Sbjct: 52 SSKQHT 57
>NP_065776
          Length = 861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAKQHT 7
           S+KQHT
Sbjct: 176 SSKQHT 181
>XP_006715966
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAKQHT 7
           S+KQHT
Sbjct: 176 SSKQHT 181
>XP_005250277
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAKQHT 7
           S+KQHT
Sbjct: 176 SSKQHT 181
>XP_006715965
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAKQHT 7
           S+KQHT
Sbjct: 176 SSKQHT 181
>XP_005250276
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAKQHT 7
           S+KQHT
Sbjct: 176 SSKQHT 181
>XP_006715964
          Length = 964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAKQHT 7
           S+KQHT
Sbjct: 176 SSKQHT 181
>XP_006715963
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SAKQHT 7
           S+KQHT
Sbjct: 176 SSKQHT 181
>XP_006715806
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LSAKQHTAK 9
          L+ K HT+K
Sbjct: 83 LTLKHHTSK 91
>XP_006715805
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LSAKQHTAK 9
          L+ K HT+K
Sbjct: 81 LTLKHHTSK 89
>XP_006713075
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           S K HTAK
Sbjct: 157 SDKPHTAK 164
>XP_005264983
          Length = 1209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           S K HTAK
Sbjct: 157 SDKPHTAK 164
>XP_005264981
          Length = 1290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           S K HTAK
Sbjct: 157 SDKPHTAK 164
>XP_005264980
          Length = 1313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           S K HTAK
Sbjct: 157 SDKPHTAK 164
>XP_006713074
          Length = 1318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           S K HTAK
Sbjct: 157 SDKPHTAK 164
>XP_005264979
          Length = 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           S K HTAK
Sbjct: 157 SDKPHTAK 164
>XP_005264978
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SAKQHTAK 9
           S K HTAK
Sbjct: 157 SDKPHTAK 164
>XP_006711326
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSAKQHTAK 9
           +SAK+ TAK
Sbjct: 344 ISAKKGTAK 352
>XP_005273145
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSAKQHTAK 9
           +SAK+ TAK
Sbjct: 344 ISAKKGTAK 352
>XP_006711325
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSAKQHTAK 9
           +SAK+ TAK
Sbjct: 344 ISAKKGTAK 352
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.104    0.260 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 522,815
Number of extensions: 379
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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