Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_570711                                                              18    1482
NP_570712                                                              18    1482
NP_570714                                                              18    1482
NP_570713                                                              18    1482
NP_570716                                                              18    1482
NP_000235                                                              18    1482
NP_570715                                                              18    1482
XP_006718620                                                           18    1482
XP_005274059                                                           18    1482
XP_005274060                                                           18    1482
XP_005274058                                                           18    1482
NP_787074                                                              16    5631
NP_683762                                                              16    5631
NP_705838                                                              15    9605
NP_001229243                                                           15    9605
NP_004712                                                              15    9605
NP_001229246                                                           15    9605
>NP_570711
          Length = 610

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 573 SAIKLQLT 580
>NP_570712
          Length = 615

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 578 SAIKLQLT 585
>NP_570714
          Length = 615

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 578 SAIKLQLT 585
>NP_570713
          Length = 615

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 578 SAIKLQLT 585
>NP_570716
          Length = 615

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 578 SAIKLQLT 585
>NP_000235
          Length = 615

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 578 SAIKLQLT 585
>NP_570715
          Length = 615

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 578 SAIKLQLT 585
>XP_006718620
          Length = 610

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 573 SAIKLQLT 580
>XP_005274059
          Length = 610

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 573 SAIKLQLT 580
>XP_005274060
          Length = 610

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 573 SAIKLQLT 580
>XP_005274058
          Length = 610

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SAIKLQLT
Sbjct: 573 SAIKLQLT 580
>NP_787074
          Length = 459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           SA+KLQL+
Sbjct: 323 SAVKLQLS 330
>NP_683762
          Length = 278

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SAIKLQLT 9
           S++KLQLT
Sbjct: 98  SSLKLQLT 105
>NP_705838
          Length = 4069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LSAIKLQL 8
            +SA+K+QL
Sbjct: 3542 ISAVKVQL 3549
>NP_001229243
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LSAIKLQL 8
           LSAI LQL
Sbjct: 486 LSAIMLQL 493
>NP_004712
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LSAIKLQL 8
           LSAI LQL
Sbjct: 486 LSAIMLQL 493
>NP_001229246
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LSAIKLQL 8
           LSAI LQL
Sbjct: 279 LSAIMLQL 286
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.131    0.296 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 293,639
Number of extensions: 263
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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