Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              17    2528
NP_068804                                                              17    2528
NP_001005407                                                           17    2528
NP_066921                                                              17    2528
XP_006721028                                                           17    2528
XP_006721027                                                           17    2528
XP_005255709                                                           17    2528
XP_006721026                                                           17    2528
NP_055426                                                              17    3301
XP_005273638                                                           17    3301
XP_005273637                                                           17    3301
XP_005273635                                                           17    3301
XP_005273634                                                           17    3301
XP_005248757                                                           17    3301
XP_006715468                                                           17    3301
XP_005248756                                                           17    3301
XP_006715467                                                           17    3301
NP_064630                                                              17    4312
XP_005267114                                                           17    4312
NP_003471                                                              16    5631
XP_006719217                                                           16    5631
XP_005253542                                                           16    5631
NP_079541                                                              16    7355
NP_001138866                                                           16    7355
NP_001138864                                                           16    7355
NP_001032409                                                           16    7355
NP_001006945                                                           16    7355
NP_003933                                                              16    7355
XP_005274438                                                           16    7355
XP_005274437                                                           16    7355
XP_005274436                                                           16    7355
XP_006718798                                                           16    7355
XP_005265556                                                           16    7355
XP_005265552                                                           16    7355
NP_115514                                                              16    7355
NP_001032410                                                           16    7355
NP_055191                                                              16    7355
NP_690867                                                              16    7355
NP_005873                                                              15    9605
NP_001017405                                                           15    9605
NP_006030                                                              15    9605
NP_476499                                                              15    9605
NP_036298                                                              15    9605
NP_001271308                                                           15    9605
NP_001271307                                                           15    9605
NP_001271306                                                           15    9605
NP_001027025                                                           15    9605
NP_001264058                                                           15    9605
NP_065933                                                              15    9605
NP_002603                                                              15    9605
NP_835258                                                              15    9605
NP_055379                                                              15    9605
NP_060298                                                              15    9605
NP_001264055                                                           15    9605
NP_653288                                                              15    9605
XP_006726638                                                           15    9605
XP_006720883                                                           15    9605
XP_005254569                                                           15    9605
XP_005254566                                                           15    9605
XP_005263467                                                           15    9605
XP_006716817                                                           15    9605
XP_005251496                                                           15    9605
XP_005272300                                                           15    9605
XP_006713914                                                           15    9605
XP_006713913                                                           15    9605
XP_006713912                                                           15    9605
XP_001714489                                                           15    9605
>NP_004251
          Length = 1208

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LRSRLLCKQ 9
           LRSRLL KQ
Sbjct: 369 LRSRLLRKQ 377
>NP_068804
          Length = 257

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  RSRLLCKQ 9
          RSR LC+Q
Sbjct: 36 RSRCLCRQ 43
>NP_001005407
          Length = 2347

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SRLLCKQ 9
            SRLLC+Q
Sbjct: 2004 SRLLCRQ 2010
>NP_066921
          Length = 2353

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SRLLCKQ 9
            SRLLC+Q
Sbjct: 2010 SRLLCRQ 2016
>XP_006721028
          Length = 2336

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SRLLCKQ 9
            SRLLC+Q
Sbjct: 1993 SRLLCRQ 1999
>XP_006721027
          Length = 2342

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SRLLCKQ 9
            SRLLC+Q
Sbjct: 1999 SRLLCRQ 2005
>XP_005255709
          Length = 2347

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SRLLCKQ 9
            SRLLC+Q
Sbjct: 2004 SRLLCRQ 2010
>XP_006721026
          Length = 2358

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    SRLLCKQ 9
            SRLLC+Q
Sbjct: 2015 SRLLCRQ 2021
>NP_055426
          Length = 5596

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LRSRLLCK 8
            LRS +LCK
Sbjct: 3506 LRSHVLCK 3513
>XP_005273638
          Length = 1228

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    RSRLLCK 8
            RSRL CK
Sbjct: 1149 RSRLFCK 1155
>XP_005273637
          Length = 1228

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    RSRLLCK 8
            RSRL CK
Sbjct: 1149 RSRLFCK 1155
>XP_005273635
          Length = 1282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    RSRLLCK 8
            RSRL CK
Sbjct: 1203 RSRLFCK 1209
>XP_005273634
          Length = 1282

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    RSRLLCK 8
            RSRL CK
Sbjct: 1203 RSRLFCK 1209
>XP_005248757
          Length = 3591

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LRSRLLCK 8
            LRS +LCK
Sbjct: 1501 LRSHVLCK 1508
>XP_006715468
          Length = 3744

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LRSRLLCK 8
            LRS +LCK
Sbjct: 1654 LRSHVLCK 1661
>XP_005248756
          Length = 3905

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LRSRLLCK 8
            LRS +LCK
Sbjct: 1815 LRSHVLCK 1822
>XP_006715467
          Length = 5550

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LRSRLLCK 8
            LRS +LCK
Sbjct: 3506 LRSHVLCK 3513
>NP_064630
          Length = 1543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RSRLLCKQ 9
           R+R+LC Q
Sbjct: 904 RTRMLCSQ 911
>XP_005267114
          Length = 1543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RSRLLCKQ 9
           R+R+LC Q
Sbjct: 904 RTRMLCSQ 911
>NP_003471
          Length = 173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLLCKQ 9
           SRL+CK+
Sbjct: 125 SRLVCKE 131
>XP_006719217
          Length = 161

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLLCKQ 9
           SRL+CK+
Sbjct: 113 SRLVCKE 119
>XP_005253542
          Length = 163

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLLCKQ 9
           SRL+CK+
Sbjct: 115 SRLVCKE 121
>NP_079541
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RSRLLCKQ 9
           R+RL+C++
Sbjct: 281 RNRLICRR 288
>NP_001138866
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RSRLLCKQ 9
           R+RL+C++
Sbjct: 222 RNRLICRR 229
>NP_001138864
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RSRLLCKQ 9
           R+RL+C++
Sbjct: 281 RNRLICRR 288
>NP_001032409
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 806 LTHRLLCK 813
>NP_001006945
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 272 LLQRLLCK 279
>NP_003933
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 272 LLQRLLCK 279
>XP_005274438
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 209 LLQRLLCK 216
>XP_005274437
          Length = 717

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 272 LLQRLLCK 279
>XP_005274436
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 272 LLQRLLCK 279
>XP_006718798
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 272 LLQRLLCK 279
>XP_005265556
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RSRLLCKQ 9
           R+RL+C++
Sbjct: 281 RNRLICRR 288
>XP_005265552
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RSRLLCKQ 9
           R+RL+C++
Sbjct: 281 RNRLICRR 288
>NP_115514
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LRSRLLCKQ 9
           L  RLLC++
Sbjct: 418 LADRLLCRE 426
>NP_001032410
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 806 LTHRLLCK 813
>NP_055191
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRSRLLCK 8
           L  RLLCK
Sbjct: 806 LTHRLLCK 813
>NP_690867
          Length = 674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LRSRLLCKQ 9
           L  RLLC++
Sbjct: 418 LADRLLCRE 426
>NP_005873
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 295 SRLVCK 300
>NP_001017405
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 336 SRLVCK 341
>NP_006030
          Length = 1479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RSRLLCKQ 9
           R+R +C+Q
Sbjct: 639 RARYICRQ 646
>NP_476499
          Length = 303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  RSRLLCKQ 9
          RSR LC +
Sbjct: 44 RSRCLCSE 51
>NP_036298
          Length = 956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LRSRLLC 7
           LRS L+C
Sbjct: 614 LRSNLIC 620
>NP_001271308
          Length = 146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LRSRLLCKQ 9
          ++ RLLC Q
Sbjct: 34 VKLRLLCSQ 42
>NP_001271307
          Length = 113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LRSRLLCKQ 9
          ++ RLLC Q
Sbjct: 28 VKLRLLCSQ 36
>NP_001271306
          Length = 140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LRSRLLCKQ 9
          ++ RLLC Q
Sbjct: 28 VKLRLLCSQ 36
>NP_001027025
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LRSRLLCK 8
          L SRL+C+
Sbjct: 70 LLSRLICR 77
>NP_001264058
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RLLCKQ 9
           RLLCK+
Sbjct: 959 RLLCKR 964
>NP_065933
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRSRLLCKQ 9
           L SRL+C++
Sbjct: 350 LLSRLICQR 358
>NP_002603
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRLLCKQ 9
           SR+LC Q
Sbjct: 211 SRMLCDQ 217
>NP_835258
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 137 SRLVCK 142
>NP_055379
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 142 SRLVCK 147
>NP_060298
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LRSRLLCKQ 9
          ++ RLLC Q
Sbjct: 28 VKLRLLCSQ 36
>NP_001264055
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RLLCKQ 9
            RLLCK+
Sbjct: 1017 RLLCKR 1022
>NP_653288
          Length = 1061

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RLLCKQ 9
            RLLCK+
Sbjct: 1016 RLLCKR 1021
>XP_006726638
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LRSRLLCKQ 9
           ++ RLLC Q
Sbjct: 169 VKLRLLCSQ 177
>XP_006720883
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LRSRLLCKQ 9
           ++ RLLC Q
Sbjct: 169 VKLRLLCSQ 177
>XP_005254569
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LRSRLLCKQ 9
          ++ RLLC Q
Sbjct: 55 VKLRLLCSQ 63
>XP_005254566
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LRSRLLCKQ 9
          ++ RLLC Q
Sbjct: 55 VKLRLLCSQ 63
>XP_005263467
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 126 SRLVCK 131
>XP_006716817
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LRSRLLC 7
           LRS L+C
Sbjct: 139 LRSNLIC 145
>XP_005251496
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LRSRLLC 7
           LRS L+C
Sbjct: 614 LRSNLIC 620
>XP_005272300
          Length = 395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 335 SRLVCK 340
>XP_006713914
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 288 SRLVCK 293
>XP_006713913
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 335 SRLVCK 340
>XP_006713912
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   SRLLCK 8
           SRL+CK
Sbjct: 336 SRLVCK 341
>XP_001714489
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LRSRLLCKQ 9
           ++ RLLC Q
Sbjct: 182 VKLRLLCSQ 190
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.143    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 648,631
Number of extensions: 771
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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