Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004662                                                              17    2528
NP_775298                                                              17    2528
XP_006722636                                                           17    2528
XP_005258440                                                           17    2528
XP_005258439                                                           17    2528
XP_005258438                                                           17    2528
XP_005258436                                                           17    2528
XP_005258434                                                           17    2528
XP_006722635                                                           17    2528
XP_006722634                                                           17    2528
NP_037417                                                              17    4312
NP_001164100                                                           16    5631
NP_060250                                                              16    5631
NP_065971                                                              16    5631
NP_079410                                                              16    5631
NP_061330                                                              16    5631
NP_115597                                                              16    5631
XP_006723946                                                           16    5631
XP_005260632                                                           16    5631
XP_005260631                                                           16    5631
XP_005260630                                                           16    5631
XP_005256233                                                           16    5631
XP_005256232                                                           16    5631
XP_005256231                                                           16    5631
XP_005256229                                                           16    5631
XP_005256228                                                           16    5631
XP_005256227                                                           16    5631
XP_006721346                                                           16    5631
XP_005256226                                                           16    5631
XP_006721345                                                           16    5631
XP_006721344                                                           16    5631
XP_006721343                                                           16    5631
XP_005256225                                                           16    5631
XP_006716523                                                           16    5631
XP_006716522                                                           16    5631
XP_005251324                                                           16    5631
XP_005251323                                                           16    5631
XP_006713783                                                           16    5631
XP_005247745                                                           16    5631
XP_006713782                                                           16    5631
NP_006497                                                              16    5631
NP_056372                                                              16    7355
NP_005843                                                              16    7355
NP_001005273                                                           16    7355
NP_055646                                                              16    7355
XP_006721493                                                           16    7355
XP_005256488                                                           16    7355
XP_006721492                                                           16    7355
XP_006721491                                                           16    7355
XP_006721490                                                           16    7355
XP_006721489                                                           16    7355
XP_006721488                                                           16    7355
XP_005256486                                                           16    7355
XP_005256485                                                           16    7355
XP_006721487                                                           16    7355
XP_006721486                                                           16    7355
XP_005256484                                                           16    7355
XP_006713495                                                           16    7355
NP_001005271                                                           16    7355
NP_001073893                                                           15    9605
NP_060417                                                              15    9605
XP_006721547                                                           15    9605
XP_005256611                                                           15    9605
XP_005256609                                                           15    9605
XP_005256607                                                           15    9605
XP_005256608                                                           15    9605
XP_006721546                                                           15    9605
XP_005256606                                                           15    9605
>NP_004662
          Length = 621

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 166 LVQSSIQRF 174
>NP_775298
          Length = 572

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 166 LVQSSIQRF 174
>XP_006722636
          Length = 611

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 205 LVQSSIQRF 213
>XP_005258440
          Length = 613

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 157 LVQSSIQRF 165
>XP_005258439
          Length = 613

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 157 LVQSSIQRF 165
>XP_005258438
          Length = 613

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 157 LVQSSIQRF 165
>XP_005258436
          Length = 622

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 166 LVQSSIQRF 174
>XP_005258434
          Length = 626

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 170 LVQSSIQRF 178
>XP_006722635
          Length = 660

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 205 LVQSSIQRF 213
>XP_006722634
          Length = 661

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           L QSS+QRF
Sbjct: 205 LVQSSIQRF 213
>NP_037417
          Length = 731

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  LRQSSVQRF 9
          ++QSS+Q+F
Sbjct: 87 IKQSSLQKF 95
>NP_001164100
          Length = 2581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1187 LRQAAIDRF 1195
>NP_060250
          Length = 2997

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1344 LRQAAIDRF 1352
>NP_065971
          Length = 2302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 908 LRQAAIDRF 916
>NP_079410
          Length = 2881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>NP_061330
          Length = 511

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RQSSVQRF 9
           RQS +Q+F
Sbjct: 170 RQSEIQKF 177
>NP_115597
          Length = 2715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 837 LRQAAIDRF 845
>XP_006723946
          Length = 1414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 837 LRQAAIDRF 845
>XP_005260632
          Length = 2377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 837 LRQAAIDRF 845
>XP_005260631
          Length = 2667

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 789 LRQAAIDRF 797
>XP_005260630
          Length = 2693

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 815 LRQAAIDRF 823
>XP_005256233
          Length = 2391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 729 LRQAAIDRF 737
>XP_005256232
          Length = 2424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 762 LRQAAIDRF 770
>XP_005256231
          Length = 2573

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_005256229
          Length = 2881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_005256228
          Length = 2882

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_005256227
          Length = 2897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_006721346
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_005256226
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_006721345
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_006721344
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_006721343
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_005256225
          Length = 2898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1236 LRQAAIDRF 1244
>XP_006716523
          Length = 1912

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 259 LRQAAIDRF 267
>XP_006716522
          Length = 2192

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRQSSVQRF 9
           LRQ+++ RF
Sbjct: 539 LRQAAIDRF 547
>XP_005251324
          Length = 2996

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1344 LRQAAIDRF 1352
>XP_005251323
          Length = 2997

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRQSSVQRF 9
            LRQ+++ RF
Sbjct: 1344 LRQAAIDRF 1352
>XP_006713783
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRQSSVQRF 9
           LRQ + QRF
Sbjct: 264 LRQMATQRF 272
>XP_005247745
          Length = 850

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRQSSVQRF 9
           LRQ + QRF
Sbjct: 485 LRQMATQRF 493
>XP_006713782
          Length = 854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRQSSVQRF 9
           LRQ + QRF
Sbjct: 485 LRQMATQRF 493
>NP_006497
          Length = 849

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRQSSVQRF 9
           LRQ + QRF
Sbjct: 485 LRQMATQRF 493
>NP_056372
          Length = 1954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1078 LRQEAIDRF 1086
>NP_005843
          Length = 1966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1114 LRQEAIDRF 1122
>NP_001005273
          Length = 2000

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1114 LRQEAIDRF 1122
>NP_055646
          Length = 2925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRQSSVQRF 9
           L+Q  VQRF
Sbjct: 353 LKQEVVQRF 361
>XP_006721493
          Length = 2056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1169 LRQEAIDRF 1177
>XP_005256488
          Length = 1185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>XP_006721492
          Length = 1924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>XP_006721491
          Length = 2025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>XP_006721490
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1094 LRQEAIDRF 1102
>XP_006721489
          Length = 2045

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>XP_006721488
          Length = 2056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1114 LRQEAIDRF 1122
>XP_005256486
          Length = 2060

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>XP_005256485
          Length = 2080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>XP_006721487
          Length = 2111

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1169 LRQEAIDRF 1177
>XP_006721486
          Length = 2114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>XP_005256484
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>XP_006713495
          Length = 2969

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRQSSVQRF 9
           L+Q  VQRF
Sbjct: 397 LKQEVVQRF 405
>NP_001005271
          Length = 2059

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LRQSSVQRF 9
            LRQ ++ RF
Sbjct: 1173 LRQEAIDRF 1181
>NP_001073893
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRQSSVQR 8
           LR+S VQR
Sbjct: 360 LRESRVQR 367
>NP_060417
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RQSSVQRF 9
           RQS  QRF
Sbjct: 308 RQSVAQRF 315
>XP_006721547
          Length = 1638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRQSSVQR 8
           LR+S VQR
Sbjct: 360 LRESRVQR 367
>XP_005256611
          Length = 1643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRQSSVQR 8
           LR+S VQR
Sbjct: 360 LRESRVQR 367
>XP_005256609
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRQSSVQR 8
           LR+S VQR
Sbjct: 360 LRESRVQR 367
>XP_005256607
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRQSSVQR 8
           LR+S VQR
Sbjct: 360 LRESRVQR 367
>XP_005256608
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRQSSVQR 8
           LR+S VQR
Sbjct: 360 LRESRVQR 367
>XP_006721546
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRQSSVQR 8
           LR+S VQR
Sbjct: 360 LRESRVQR 367
>XP_005256606
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRQSSVQR 8
           LR+S VQR
Sbjct: 360 LRESRVQR 367
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.132    0.330 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 301,533
Number of extensions: 448
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package