Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              17    2528
XP_006718908                                                           17    2528
XP_005271621                                                           17    2528
XP_006718907                                                           17    2528
XP_006718906                                                           17    2528
XP_005271619                                                           17    2528
XP_005271618                                                           17    2528
NP_001165882                                                           17    4312
NP_001165883                                                           17    4312
NP_620409                                                              17    4312
XP_006710999                                                           17    4312
XP_006710998                                                           17    4312
NP_057434                                                              16    5631
NP_891989                                                              16    5631
NP_065972                                                              16    5631
NP_073572                                                              16    5631
NP_891991                                                              16    5631
NP_443161                                                              16    5631
NP_115766                                                              16    5631
XP_006720224                                                           16    5631
XP_005267794                                                           16    5631
XP_005267793                                                           16    5631
XP_005267792                                                           16    5631
XP_006720223                                                           16    5631
XP_006710380                                                           16    5631
XP_005245788                                                           16    5631
XP_006710379                                                           16    5631
XP_006710378                                                           16    5631
NP_055654                                                              16    7355
NP_055771                                                              16    7355
NP_001258862                                                           16    7355
NP_001264282                                                           16    7355
NP_115558                                                              16    7355
XP_005271517                                                           16    7355
XP_006718857                                                           16    7355
XP_005271516                                                           16    7355
XP_005271515                                                           16    7355
XP_005271514                                                           16    7355
XP_005271513                                                           16    7355
XP_005271512                                                           16    7355
XP_005271511                                                           16    7355
XP_006718856                                                           16    7355
XP_006718855                                                           16    7355
XP_006718854                                                           16    7355
XP_006718853                                                           16    7355
XP_005271510                                                           16    7355
XP_005271509                                                           16    7355
XP_006718852                                                           16    7355
XP_006718851                                                           16    7355
XP_005264389                                                           16    7355
XP_005270453                                                           16    7355
XP_005270452                                                           16    7355
XP_005270451                                                           16    7355
NP_006836                                                              16    7355
NP_620059                                                              15    9605
NP_001182226                                                           15    9605
NP_001182225                                                           15    9605
NP_064612                                                              15    9605
XP_005267409                                                           15    9605
XP_006720108                                                           15    9605
XP_005273841                                                           15    9605
XP_005273840                                                           15    9605
XP_005273839                                                           15    9605
XP_006718500                                                           15    9605
XP_005272199                                                           15    9605
NP_612480                                                              15    9605
NP_055644                                                              15    9605
>NP_000042
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LRITQQK 7
            LRITQQK
Sbjct: 1574 LRITQQK 1580
>XP_006718908
          Length = 1708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LRITQQK 7
           LRITQQK
Sbjct: 226 LRITQQK 232
>XP_005271621
          Length = 2708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LRITQQK 7
            LRITQQK
Sbjct: 1226 LRITQQK 1232
>XP_006718907
          Length = 3050

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LRITQQK 7
            LRITQQK
Sbjct: 1568 LRITQQK 1574
>XP_006718906
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LRITQQK 7
            LRITQQK
Sbjct: 1574 LRITQQK 1580
>XP_005271619
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LRITQQK 7
            LRITQQK
Sbjct: 1574 LRITQQK 1580
>XP_005271618
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LRITQQK 7
            LRITQQK
Sbjct: 1574 LRITQQK 1580
>NP_001165882
          Length = 522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LRITQQKN 8
           LRIT+Q+N
Sbjct: 407 LRITRQQN 414
>NP_001165883
          Length = 524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LRITQQKN 8
           LRIT+Q+N
Sbjct: 409 LRITRQQN 416
>NP_620409
          Length = 524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LRITQQKN 8
           LRIT+Q+N
Sbjct: 409 LRITRQQN 416
>XP_006710999
          Length = 463

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LRITQQKN 8
           LRIT+Q+N
Sbjct: 348 LRITRQQN 355
>XP_006710998
          Length = 524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LRITQQKN 8
           LRIT+Q+N
Sbjct: 409 LRITRQQN 416
>NP_057434
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1076 LRVTQQEKE 1084
>NP_891989
          Length = 2046

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1789 LRVTQQEKE 1797
>NP_065972
          Length = 2133

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1789 LRVTQQEKE 1797
>NP_073572
          Length = 528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 237 LRLEQQKQQ 245
>NP_891991
          Length = 2090

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1789 LRVTQQEKE 1797
>NP_443161
          Length = 1412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RITQQKNQ 9
            +ITQ KNQ
Sbjct: 1293 KITQLKNQ 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQ+KN+
Sbjct: 730 ITQEKNR 736
>NP_115766
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  RITQQKNQ 9
          RITQ+K Q
Sbjct: 32 RITQRKKQ 39
>XP_006720224
          Length = 1276

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1076 LRVTQQEKE 1084
>XP_005267794
          Length = 1379

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1035 LRVTQQEKE 1043
>XP_005267793
          Length = 1390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1046 LRVTQQEKE 1054
>XP_005267792
          Length = 1420

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1076 LRVTQQEKE 1084
>XP_006720223
          Length = 1989

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LRITQQKNQ 9
            LR+TQQ+ +
Sbjct: 1789 LRVTQQEKE 1797
>XP_006710380
          Length = 1398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RITQQKNQ 9
            +ITQ KNQ
Sbjct: 1279 KITQLKNQ 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQ+KN+
Sbjct: 752 ITQEKNR 758
>XP_005245788
          Length = 1434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RITQQKNQ 9
            +ITQ KNQ
Sbjct: 1315 KITQLKNQ 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQ+KN+
Sbjct: 752 ITQEKNR 758
>XP_006710379
          Length = 1452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RITQQKNQ 9
            +ITQ KNQ
Sbjct: 1315 KITQLKNQ 1322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQ+KN+
Sbjct: 752 ITQEKNR 758
>XP_006710378
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RITQQKNQ 9
            +ITQ KNQ
Sbjct: 1314 KITQLKNQ 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQ+KN+
Sbjct: 752 ITQEKNR 758
>NP_055654
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   RITQQKN 8
           RITQ KN
Sbjct: 297 RITQYKN 303
>NP_055771
          Length = 1460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 634 LRLHQQKEQ 642
>NP_001258862
          Length = 1455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 637 LRLHQQKEQ 645
>NP_001264282
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  RITQQKNQ 9
          RITQ  NQ
Sbjct: 27 RITQTNNQ 34
>NP_115558
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RITQQKNQ 9
           +ITQ+KN+
Sbjct: 247 QITQRKNE 254
>XP_005271517
          Length = 1350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 524 LRLHQQKEQ 532
>XP_006718857
          Length = 1434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 608 LRLHQQKEQ 616
>XP_005271516
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 611 LRLHQQKEQ 619
>XP_005271515
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 611 LRLHQQKEQ 619
>XP_005271514
          Length = 1455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 637 LRLHQQKEQ 645
>XP_005271513
          Length = 1460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 634 LRLHQQKEQ 642
>XP_005271512
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 637 LRLHQQKEQ 645
>XP_005271511
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRITQQKNQ 9
           LR+ QQK Q
Sbjct: 637 LRLHQQKEQ 645
>XP_006718856
          Length = 1976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LRITQQKNQ 9
            LR+ QQK Q
Sbjct: 1150 LRLHQQKEQ 1158
>XP_006718855
          Length = 1979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LRITQQKNQ 9
            LR+ QQK Q
Sbjct: 1153 LRLHQQKEQ 1161
>XP_006718854
          Length = 1999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LRITQQKNQ 9
            LR+ QQK Q
Sbjct: 1173 LRLHQQKEQ 1181
>XP_006718853
          Length = 2017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LRITQQKNQ 9
            LR+ QQK Q
Sbjct: 1199 LRLHQQKEQ 1207
>XP_005271510
          Length = 2022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LRITQQKNQ 9
            LR+ QQK Q
Sbjct: 1196 LRLHQQKEQ 1204
>XP_005271509
          Length = 2024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LRITQQKNQ 9
            LR+ QQK Q
Sbjct: 1199 LRLHQQKEQ 1207
>XP_006718852
          Length = 2025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LRITQQKNQ 9
            LR+ QQK Q
Sbjct: 1199 LRLHQQKEQ 1207
>XP_006718851
          Length = 2025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LRITQQKNQ 9
            LR+ QQK Q
Sbjct: 1199 LRLHQQKEQ 1207
>XP_005264389
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRITQQKNQ 9
           LR+T+ K+Q
Sbjct: 880 LRVTEPKDQ 888
>XP_005270453
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LRITQQKN 8
          LRIT Q+N
Sbjct: 66 LRITAQEN 73
>XP_005270452
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRITQQKN 8
           LRIT Q+N
Sbjct: 120 LRITAQEN 127
>XP_005270451
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRITQQKN 8
           LRIT Q+N
Sbjct: 111 LRITAQEN 118
>NP_006836
          Length = 725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRITQQKN 8
           LRIT Q+N
Sbjct: 120 LRITAQEN 127
>NP_620059
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQQ+N+
Sbjct: 379 ITQQQNE 385
>NP_001182226
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQQ+N+
Sbjct: 379 ITQQQNE 385
>NP_001182225
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQQ+N+
Sbjct: 379 ITQQQNE 385
>NP_064612
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRITQQKNQ 9
           LR+ Q+K+Q
Sbjct: 108 LRVEQRKHQ 116
>XP_005267409
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQQ+N+
Sbjct: 343 ITQQQNE 349
>XP_006720108
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITQQKNQ 9
           ITQQ+N+
Sbjct: 379 ITQQQNE 385
>XP_005273841
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LRITQQK 7
          LR+TQQ+
Sbjct: 41 LRVTQQE 47
>XP_005273840
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LRITQQK 7
          LR+TQQ+
Sbjct: 41 LRVTQQE 47
>XP_005273839
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LRITQQK 7
          LR+TQQ+
Sbjct: 41 LRVTQQE 47
>XP_006718500
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LRITQQK 7
          LR+TQQ+
Sbjct: 41 LRVTQQE 47
>XP_005272199
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRITQQKN 8
           LRI  QKN
Sbjct: 857 LRINAQKN 864
>NP_612480
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LRITQQK 7
          LR+TQQ+
Sbjct: 41 LRVTQQE 47
>NP_055644
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LRITQQKN 8
           LRI  QKN
Sbjct: 857 LRINAQKN 864
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.123    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 473,534
Number of extensions: 699
Number of successful extensions: 72
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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