Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              20     390
NP_005913                                                              20     390
XP_005267046                                                           20     390
XP_005267045                                                           20     390
NP_004230                                                              17    2528
XP_005268272                                                           17    2528
XP_005268271                                                           17    2528
XP_005268270                                                           17    2528
XP_006720384                                                           17    2528
NP_001027559                                                           17    3301
NP_001027558                                                           17    3301
NP_000447                                                              17    3301
XP_005269169                                                           17    3301
NP_775759                                                              17    4312
NP_001275933                                                           17    4312
NP_001275931                                                           17    4312
NP_851322                                                              17    4312
XP_005271931                                                           17    4312
NP_001004700                                                           16    5631
NP_077277                                                              16    7355
NP_001034974                                                           16    7355
NP_001245221                                                           16    7355
NP_001129493                                                           16    7355
NP_079204                                                              16    7355
XP_006723438                                                           16    7355
XP_005259307                                                           16    7355
XP_006723437                                                           16    7355
XP_005259306                                                           16    7355
XP_006723436                                                           16    7355
XP_005259304                                                           16    7355
XP_005259305                                                           16    7355
XP_006718040                                                           16    7355
XP_006718039                                                           16    7355
NP_003477                                                              15    9605
NP_055146                                                              15    9605
NP_998765                                                              15    9605
NP_001269845                                                           15    9605
NP_055085                                                              15    9605
NP_001229965                                                           15    9605
NP_055495                                                              15    9605
NP_001119807                                                           15    9605
NP_001269848                                                           15    9605
NP_116182                                                              15    9605
NP_078988                                                              15    9605
NP_001233                                                              15    9605
NP_001073863                                                           15    9605
NP_001129965                                                           15    9605
NP_001274738                                                           15    9605
NP_001274737                                                           15    9605
NP_075048                                                              15    9605
XP_006722261                                                           15    9605
XP_005258130                                                           15    9605
XP_005251258                                                           15    9605
XP_006716508                                                           15    9605
XP_005251256                                                           15    9605
XP_006716507                                                           15    9605
XP_005251255                                                           15    9605
XP_005251254                                                           15    9605
XP_005251253                                                           15    9605
XP_005251252                                                           15    9605
XP_005251250                                                           15    9605
XP_006716506                                                           15    9605
XP_005251246                                                           15    9605
XP_005262932                                                           15    9605
XP_005271342                                                           15    9605
>NP_006715
          Length = 1558

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LRIMGTVVG 9
           LRIMGTV+G
Sbjct: 407 LRIMGTVLG 415
>NP_005913
          Length = 1608

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LRIMGTVVG 9
           LRIMGTV+G
Sbjct: 407 LRIMGTVLG 415
>XP_005267046
          Length = 1554

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LRIMGTVVG 9
           LRIMGTV+G
Sbjct: 407 LRIMGTVLG 415
>XP_005267045
          Length = 1604

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LRIMGTVVG 9
           LRIMGTV+G
Sbjct: 407 LRIMGTVLG 415
>NP_004230
          Length = 1979

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LRIMGTVVG 9
            LR+MG+++G
Sbjct: 1803 LRLMGSILG 1811
>XP_005268272
          Length = 969

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LRIMGTVVG 9
           LR+MG+++G
Sbjct: 793 LRLMGSILG 801
>XP_005268271
          Length = 1537

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LRIMGTVVG 9
            LR+MG+++G
Sbjct: 1361 LRLMGSILG 1369
>XP_005268270
          Length = 1950

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LRIMGTVVG 9
            LR+MG+++G
Sbjct: 1774 LRLMGSILG 1782
>XP_006720384
          Length = 1978

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LRIMGTVVG 9
            LR+MG+++G
Sbjct: 1802 LRLMGSILG 1810
>NP_001027559
          Length = 545

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RIMGTVVG 9
          R+MGT++G
Sbjct: 56 RVMGTLLG 63
>NP_001027558
          Length = 545

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RIMGTVVG 9
          R+MGT++G
Sbjct: 56 RVMGTLLG 63
>NP_000447
          Length = 545

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RIMGTVVG 9
          R+MGT++G
Sbjct: 56 RVMGTLLG 63
>XP_005269169
          Length = 552

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RIMGTVVG 9
          R+MGT++G
Sbjct: 63 RVMGTLLG 70
>NP_775759
          Length = 719

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIMGTVVG 9
           LRI GT+ G
Sbjct: 623 LRIFGTIPG 631
>NP_001275933
          Length = 657

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIMGTVVG 9
           LRI GT+ G
Sbjct: 561 LRIFGTIPG 569
>NP_001275931
          Length = 719

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIMGTVVG 9
           LRI GT+ G
Sbjct: 623 LRIFGTIPG 631
>NP_851322
          Length = 724

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIMGTVVG 9
           LR++GT+ G
Sbjct: 622 LRLLGTIPG 630
>XP_005271931
          Length = 719

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIMGTVVG 9
           LRI GT+ G
Sbjct: 623 LRIFGTIPG 631
>NP_001004700
          Length = 310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  MGTVVG 9
          MGTVVG
Sbjct: 34 MGTVVG 39
>NP_077277
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>NP_001034974
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>NP_001245221
          Length = 905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LRIMGTV 7
          LRIMG+V
Sbjct: 15 LRIMGSV 21
>NP_001129493
          Length = 901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LRIMGTV 7
          LRIMG+V
Sbjct: 15 LRIMGSV 21
>NP_079204
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          ++GTV+G
Sbjct: 59 VLGTVIG 65
>XP_006723438
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>XP_005259307
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>XP_006723437
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>XP_005259306
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>XP_006723436
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>XP_005259304
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>XP_005259305
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   RIMGTVVG 9
           R  GTVVG
Sbjct: 295 RCFGTVVG 302
>XP_006718040
          Length = 211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          ++GTV+G
Sbjct: 59 VLGTVIG 65
>XP_006718039
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          ++GTV+G
Sbjct: 59 VLGTVIG 65
>NP_003477
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          I+GT++G
Sbjct: 59 IVGTIIG 65
>NP_055146
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          I+GT++G
Sbjct: 53 IIGTIIG 59
>NP_998765
          Length = 849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIMGTVVG 9
           LRI GT+ G
Sbjct: 183 LRIQGTLRG 191
>NP_001269845
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 709 VQGTVVG 715
>NP_055085
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          I+GT++G
Sbjct: 39 IVGTIIG 45
>NP_001229965
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          I+GT++G
Sbjct: 39 IVGTIIG 45
>NP_055495
          Length = 2235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    RIMGTVVG 9
            R+MG +VG
Sbjct: 1040 RLMGRLVG 1047
>NP_001119807
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          I+GT++G
Sbjct: 39 IVGTIIG 45
>NP_001269848
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 719 VQGTVVG 725
>NP_116182
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LRIMGTVVG 9
           + ++GTV+G
Sbjct: 189 VEVLGTVLG 197
>NP_078988
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LRIMGTVV 8
           L+I+GT++
Sbjct: 179 LQILGTII 186
>NP_001233
          Length = 260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LRIMGTVVG 9
          L ++GT+VG
Sbjct: 9  LCVLGTLVG 17
>NP_001073863
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 779 VQGTVVG 785
>NP_001129965
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LRIMGTVVG 9
           + ++GTV+G
Sbjct: 202 VEVLGTVLG 210
>NP_001274738
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LRIMGTVVG 9
           + ++GTV+G
Sbjct: 152 VEVLGTVLG 160
>NP_001274737
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LRIMGTVVG 9
          + ++GTV+G
Sbjct: 33 VEVLGTVLG 41
>NP_075048
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IMGTVVG 9
           ++GTVVG
Sbjct: 498 LVGTVVG 504
>XP_006722261
          Length = 2092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RIMGTVVG 9
           R+MG +VG
Sbjct: 897 RLMGRLVG 904
>XP_005258130
          Length = 2234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    RIMGTVVG 9
            R+MG +VG
Sbjct: 1040 RLMGRLVG 1047
>XP_005251258
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 284 VQGTVVG 290
>XP_006716508
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 417 VQGTVVG 423
>XP_005251256
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 468 VQGTVVG 474
>XP_006716507
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 529 VQGTVVG 535
>XP_005251255
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 529 VQGTVVG 535
>XP_005251254
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 605 VQGTVVG 611
>XP_005251253
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 606 VQGTVVG 612
>XP_005251252
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 615 VQGTVVG 621
>XP_005251250
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 779 VQGTVVG 785
>XP_006716506
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 719 VQGTVVG 725
>XP_005251246
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   IMGTVVG 9
           + GTVVG
Sbjct: 779 VQGTVVG 785
>XP_005262932
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  IMGTVVG 9
          I+GT++G
Sbjct: 53 IIGTIIG 59
>XP_005271342
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LRIMGTVVG 9
           + ++GTV+G
Sbjct: 187 VEVLGTVLG 195
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.154    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,648
Number of extensions: 640
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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