Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005912                                                              18    1935
XP_005248577                                                           18    1935
XP_005248576                                                           18    1935
NP_060064                                                              17    3301
NP_207837                                                              16    5631
NP_055747                                                              16    5631
XP_005247294                                                           16    5631
XP_005247293                                                           16    5631
XP_005247292                                                           16    5631
XP_005247291                                                           16    5631
XP_005247290                                                           16    5631
XP_006713603                                                           16    5631
XP_005247289                                                           16    5631
NP_620481                                                              16    5631
NP_000248                                                              16    7355
NP_001274675                                                           16    7355
NP_001136105                                                           16    7355
NP_004470                                                              16    7355
NP_000704                                                              16    7355
NP_055123                                                              16    7355
NP_001035865                                                           16    7355
NP_003326                                                              16    7355
NP_001238784                                                           16    7355
NP_001238780                                                           16    7355
NP_001238781                                                           16    7355
NP_061909                                                              16    7355
NP_001274670                                                           16    7355
NP_001238782                                                           16    7355
XP_005256637                                                           16    7355
XP_005256636                                                           16    7355
XP_005267754                                                           16    7355
XP_005267753                                                           16    7355
XP_006716351                                                           16    7355
XP_005265487                                                           16    7355
XP_006713384                                                           16    7355
NP_543148                                                              16    7355
NP_060816                                                              16    7355
NP_570629                                                              15    9605
NP_001034439                                                           15    9605
NP_001927                                                              15    9605
NP_001277181                                                           15    9605
NP_001258825                                                           15    9605
NP_001258824                                                           15    9605
NP_079426                                                              15    9605
NP_056355                                                              15    9605
NP_057340                                                              15    9605
XP_006720533                                                           15    9605
XP_006720532                                                           15    9605
XP_005254354                                                           15    9605
XP_005254211                                                           15    9605
XP_005254210                                                           15    9605
XP_006720446                                                           15    9605
XP_005254209                                                           15    9605
XP_005254208                                                           15    9605
XP_005252741                                                           15    9605
XP_006715935                                                           15    9605
XP_006715934                                                           15    9605
XP_006711619                                                           15    9605
XP_006711618                                                           15    9605
NP_003983                                                              15    9605
NP_001123500                                                           15    9605
NP_005584                                                              15    9605
NP_001012526                                                           15    9605
>NP_005912
          Length = 1512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIAVFGAA 9
            LRIA FGAA
Sbjct: 1384 LRIADFGAA 1392
>XP_005248577
          Length = 1349

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIAVFGAA 9
            LRIA FGAA
Sbjct: 1221 LRIADFGAA 1229
>XP_005248576
          Length = 1375

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LRIAVFGAA 9
            LRIA FGAA
Sbjct: 1247 LRIADFGAA 1255
>NP_060064
          Length = 199

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  RIAVFGA 8
          R+AVFGA
Sbjct: 9  RVAVFGA 15
>NP_207837
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIAVFGAA 9
           +RI VFG A
Sbjct: 170 MRIEVFGCA 178
>NP_055747
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LRI VFG+
Sbjct: 253 LRITVFGS 260
>XP_005247294
          Length = 671

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LRI VFG+
Sbjct: 101 LRITVFGS 108
>XP_005247293
          Length = 814

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LRI VFG+
Sbjct: 253 LRITVFGS 260
>XP_005247292
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LRI VFG+
Sbjct: 253 LRITVFGS 260
>XP_005247291
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LRI VFG+
Sbjct: 253 LRITVFGS 260
>XP_005247290
          Length = 834

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LRI VFG+
Sbjct: 273 LRITVFGS 280
>XP_006713603
          Length = 843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LRI VFG+
Sbjct: 273 LRITVFGS 280
>XP_005247289
          Length = 843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LRI VFG+
Sbjct: 273 LRITVFGS 280
>NP_620481
          Length = 1235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIAVFGAA 9
           +RI VFG A
Sbjct: 145 MRIEVFGCA 153
>NP_000248
          Length = 1935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  IAVFGAA 9
          +AVFGAA
Sbjct: 6  MAVFGAA 12
>NP_001274675
          Length = 241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  IAVFGAA 9
          I+VFGAA
Sbjct: 40 ISVFGAA 46
>NP_001136105
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+ VFG+
Sbjct: 517 LRVVVFGS 524
>NP_004470
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LRIAVFGAA 9
           LR+ VFG A
Sbjct: 197 LRVDVFGRA 205
>NP_000704
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  RIAVFGA 8
          +IA+FGA
Sbjct: 5  KIAIFGA 11
>NP_055123
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+ VFG+
Sbjct: 517 LRVVVFGS 524
>NP_001035865
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IAVFGAA 9
           I+VFGAA
Sbjct: 139 ISVFGAA 145
>NP_003326
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RIAVFGA 8
           +IAVFGA
Sbjct: 418 QIAVFGA 424
>NP_001238784
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+ VFG+
Sbjct: 131 LRVVVFGS 138
>NP_001238780
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+ VFG+
Sbjct: 131 LRVVVFGS 138
>NP_001238781
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+ VFG+
Sbjct: 131 LRVVVFGS 138
>NP_061909
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IAVFGAA 9
           I+VFGAA
Sbjct: 169 ISVFGAA 175
>NP_001274670
          Length = 308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IAVFGAA 9
           I+VFGAA
Sbjct: 107 ISVFGAA 113
>NP_001238782
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+ VFG+
Sbjct: 131 LRVVVFGS 138
>XP_005256637
          Length = 879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+ VFG+
Sbjct: 517 LRVVVFGS 524
>XP_005256636
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+ VFG+
Sbjct: 517 LRVVVFGS 524
>XP_005267754
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  IAVFGAA 9
          +AVFGAA
Sbjct: 6  MAVFGAA 12
>XP_005267753
          Length = 1935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  IAVFGAA 9
          +AVFGAA
Sbjct: 6  MAVFGAA 12
>XP_006716351
          Length = 865

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LRIAVFG 7
           L++AVFG
Sbjct: 603 LKVAVFG 609
>XP_005265487
          Length = 987

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RIAVFGA 8
           +IAVFGA
Sbjct: 418 QIAVFGA 424
>XP_006713384
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RIAVFGA 8
           +IAVFGA
Sbjct: 418 QIAVFGA 424
>NP_543148
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LRIAVFG 7
           L++AVFG
Sbjct: 691 LKVAVFG 697
>NP_060816
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RIAVFGAA 9
           R+A FGAA
Sbjct: 141 RLAEFGAA 148
>NP_570629
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RIAVFG 7
           R+AVFG
Sbjct: 705 RVAVFG 710
>NP_001034439
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RIAVFG 7
           R+AVFG
Sbjct: 641 RVAVFG 646
>NP_001927
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RIAVFG 7
           R+AVFG
Sbjct: 643 RVAVFG 648
>NP_001277181
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RIAVFG 7
           R+AVFG
Sbjct: 598 RVAVFG 603
>NP_001258825
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+A FGA
Sbjct: 298 LRLADFGA 305
>NP_001258824
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+A FGA
Sbjct: 346 LRLADFGA 353
>NP_079426
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+A FGA
Sbjct: 428 LRLADFGA 435
>NP_056355
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LRIAVFG 7
            LR+A+FG
Sbjct: 1244 LRLALFG 1250
>NP_057340
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LRIAVFG 7
          LR+A+FG
Sbjct: 11 LRLALFG 17
>XP_006720533
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LRIAVFG 7
           LR+A+FG
Sbjct: 949 LRLALFG 955
>XP_006720532
          Length = 1333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LRIAVFG 7
            LR+A+FG
Sbjct: 1184 LRLALFG 1190
>XP_005254354
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LRIAVFG 7
            LR+A+FG
Sbjct: 1244 LRLALFG 1250
>XP_005254211
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIAVFGAA 9
           +R+A FG+A
Sbjct: 95  IRVADFGSA 103
>XP_005254210
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIAVFGAA 9
           +R+A FG+A
Sbjct: 316 IRVADFGSA 324
>XP_006720446
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIAVFGAA 9
           +R+A FG+A
Sbjct: 330 IRVADFGSA 338
>XP_005254209
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIAVFGAA 9
           +R+A FG+A
Sbjct: 330 IRVADFGSA 338
>XP_005254208
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIAVFGAA 9
           +R+A FG+A
Sbjct: 478 IRVADFGSA 486
>XP_005252741
          Length = 151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LRIAVFGAA 9
          LR+A  GAA
Sbjct: 64 LRVAAAGAA 72
>XP_006715935
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RIAVFG 7
           R+AVFG
Sbjct: 644 RVAVFG 649
>XP_006715934
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RIAVFG 7
           R+AVFG
Sbjct: 644 RVAVFG 649
>XP_006711619
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+A FGA
Sbjct: 379 LRLADFGA 386
>XP_006711618
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LRIAVFGA 8
           LR+A FGA
Sbjct: 428 LRLADFGA 435
>NP_003983
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIAVFGAA 9
           +R+A FG+A
Sbjct: 316 IRVADFGSA 324
>NP_001123500
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LRIAVFGAA 9
           +R+A FG+A
Sbjct: 464 IRVADFGSA 472
>NP_005584
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  RIAVFGA 8
          R+A FGA
Sbjct: 35 RVAAFGA 41
>NP_001012526
          Length = 151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LRIAVFGAA 9
          LR+A  GAA
Sbjct: 64 LRVAAAGAA 72
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.150    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 337,296
Number of extensions: 494
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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