Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              18    1482
NP_898884                                                              16    5631
XP_006713666                                                           16    5631
XP_006713665                                                           16    5631
NP_127493                                                              16    7355
NP_127494                                                              16    7355
NP_001157108                                                           16    7355
NP_001509                                                              16    7355
NP_127492                                                              16    7355
XP_005250353                                                           16    7355
XP_006716008                                                           16    7355
XP_006716007                                                           16    7355
XP_006716006                                                           16    7355
XP_006716005                                                           16    7355
XP_006716004                                                           16    7355
XP_006716003                                                           16    7355
XP_006716002                                                           16    7355
XP_005250348                                                           16    7355
>NP_005219
          Length = 1210

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LREATSSKA 9
           LREATS KA
Sbjct: 747 LREATSPKA 755
>NP_898884
          Length = 1177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LREATSSK 8
           LR+ATS+K
Sbjct: 428 LRDATSTK 435
>XP_006713666
          Length = 1104

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LREATSSK 8
           LR+ATS+K
Sbjct: 355 LRDATSTK 362
>XP_006713665
          Length = 1175

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LREATSSK 8
           LR+ATS+K
Sbjct: 428 LRDATSTK 435
>NP_127493
          Length = 978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 795 IKESTSSKS 803
>NP_127494
          Length = 977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 794 IKESTSSKS 802
>NP_001157108
          Length = 976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 793 IKESTSSKS 801
>NP_001509
          Length = 957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 774 IKESTSSKS 782
>NP_127492
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 815 IKESTSSKS 823
>XP_005250353
          Length = 969

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 786 IKESTSSKS 794
>XP_006716008
          Length = 988

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 805 IKESTSSKS 813
>XP_006716007
          Length = 989

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 806 IKESTSSKS 814
>XP_006716006
          Length = 990

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 807 IKESTSSKS 815
>XP_006716005
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 815 IKESTSSKS 823
>XP_006716004
          Length = 1003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 820 IKESTSSKS 828
>XP_006716003
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 826 IKESTSSKS 834
>XP_006716002
          Length = 1010

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 827 IKESTSSKS 835
>XP_005250348
          Length = 1010

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LREATSSKA 9
           ++E+TSSK+
Sbjct: 827 IKESTSSKS 835
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.290   0.0990    0.213 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 274,574
Number of extensions: 222
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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