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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              19     665
NP_996844                                                              19     869
XP_005254439                                                           19     869
XP_006720568                                                           19     869
XP_005254438                                                           19     869
NP_002335                                                              19     869
NP_000072                                                              18    1135
XP_005273087                                                           18    1135
XP_005273086                                                           18    1135
XP_005273085                                                           18    1135
XP_005273084                                                           18    1135
NP_001274103                                                           16    5631
NP_000343                                                              16    5631
XP_006718349                                                           16    5631
NP_005237                                                              16    7355
NP_001157865                                                           16    7355
NP_031384                                                              16    7355
NP_001157864                                                           16    7355
NP_001157863                                                           16    7355
NP_055580                                                              16    7355
NP_006851                                                              16    7355
NP_001171172                                                           16    7355
NP_071373                                                              16    7355
XP_006724169                                                           16    7355
XP_005266015                                                           16    7355
XP_005271980                                                           16    7355
XP_006714636                                                           16    7355
XP_006714635                                                           16    7355
NP_056110                                                              15    9605
XP_005258159                                                           15    9605
XP_006722384                                                           15    9605

>NP_004295
          Length = 1620

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQVVVKTLP 9
            LQV VKTLP
Sbjct: 1145 LQVAVKTLP 1153



>NP_996844
          Length = 803

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQV +KTLP
Sbjct: 478 LQVAIKTLP 486



>XP_005254439
          Length = 475

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQV +KTLP
Sbjct: 150 LQVAIKTLP 158



>XP_006720568
          Length = 771

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQV +KTLP
Sbjct: 446 LQVAIKTLP 454



>XP_005254438
          Length = 819

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQV +KTLP
Sbjct: 494 LQVAIKTLP 502



>NP_002335
          Length = 864

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQV +KTLP
Sbjct: 539 LQVAIKTLP 547



>NP_000072
          Length = 3801

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQ+ VKTLP
Sbjct: 774 LQIYVKTLP 782



>XP_005273087
          Length = 2788

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQ+ VKTLP
Sbjct: 774 LQIYVKTLP 782



>XP_005273086
          Length = 3264

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQ+ VKTLP
Sbjct: 774 LQIYVKTLP 782



>XP_005273085
          Length = 3755

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQ+ VKTLP
Sbjct: 774 LQIYVKTLP 782



>XP_005273084
          Length = 3801

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQ+ VKTLP
Sbjct: 774 LQIYVKTLP 782



>NP_001274103
          Length = 1582

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LQVVVKTLP 9
            L++VVK LP
Sbjct: 1460 LKLVVKALP 1468



>NP_000343
          Length = 1581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LQVVVKTLP 9
            L++VVK LP
Sbjct: 1459 LKLVVKALP 1467



>XP_006718349
          Length = 1646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LQVVVKTLP 9
            L++VVK LP
Sbjct: 1524 LKLVVKALP 1532



>NP_005237
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQVVVKTL 8
           LQV++KTL
Sbjct: 305 LQVMLKTL 312



>NP_001157865
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQVVVKTLP 9
          LQV+ +TLP
Sbjct: 73 LQVMKQTLP 81



>NP_031384
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQV+ +TLP
Sbjct: 175 LQVMKQTLP 183



>NP_001157864
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQV+ +TLP
Sbjct: 175 LQVMKQTLP 183



>NP_001157863
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQVVVKTLP 9
          LQV+ +TLP
Sbjct: 73 LQVMKQTLP 81



>NP_055580
          Length = 145

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQVVVKTLP 9
           LQV+ +TLP
Sbjct: 107 LQVLQQTLP 115



>NP_006851
          Length = 185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LQVVVKTLP 9
          + +VVKT+P
Sbjct: 41 MDLVVKTVP 49



>NP_001171172
          Length = 186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LQVVVKTLP 9
          + +VVKT+P
Sbjct: 42 MDLVVKTVP 50



>NP_071373
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VVVKTLP 9
           +V+KTLP
Sbjct: 278 LVIKTLP 284



>XP_006724169
          Length = 186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LQVVVKTLP 9
          + +VVKT+P
Sbjct: 42 MDLVVKTVP 50



>XP_005266015
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VVVKTLP 9
           +V+KTLP
Sbjct: 278 LVIKTLP 284



>XP_005271980
          Length = 749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQVVVKTL 8
           LQV++KTL
Sbjct: 232 LQVMLKTL 239



>XP_006714636
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQVVVKTL 8
           LQV++KTL
Sbjct: 305 LQVMLKTL 312



>XP_006714635
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQVVVKTL 8
           LQV++KTL
Sbjct: 305 LQVMLKTL 312



>NP_056110
          Length = 2005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QVVVKTLP 9
            QV+V+ LP
Sbjct: 1478 QVIVEVLP 1485



>XP_005258159
          Length = 1817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QVVVKTLP 9
            QV+V+ LP
Sbjct: 1290 QVIVEVLP 1297



>XP_006722384
          Length = 1877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QVVVKTLP 9
            QV+V+ LP
Sbjct: 1350 QVIVEVLP 1357



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.140    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 355,047
Number of extensions: 493
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)