Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_853514                                                              17    2528
NP_005742                                                              17    3301
NP_671714                                                              17    3301
NP_116271                                                              17    3301
XP_006715890                                                           17    3301
XP_005250160                                                           17    3301
XP_005250159                                                           17    3301
NP_001093322                                                           16    7355
NP_001136093                                                           16    7355
NP_004248                                                              16    7355
XP_006712924                                                           16    7355
XP_006712923                                                           16    7355
NP_001091846                                                           15    9605
NP_001010890                                                           15    9605
NP_001009611                                                           15    9605
NP_001139816                                                           15    9605
NP_001013425                                                           15    9605
NP_001035362                                                           15    9605
NP_940894                                                              15    9605
NP_001008783                                                           15    9605
NP_001231785                                                           15    9605
XP_006726395                                                           15    9605
XP_005276181                                                           15    9605
XP_005276180                                                           15    9605
XP_005276179                                                           15    9605
XP_006725019                                                           15    9605
XP_006725018                                                           15    9605
XP_006711146                                                           15    9605
XP_006711145                                                           15    9605
XP_006711143                                                           15    9605
NP_001010889                                                           15    9605
>NP_853514
          Length = 1732

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQV LQKAS
Sbjct: 268 LQVSLQKAS 276
>NP_005742
          Length = 3907

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQVLLQKAS 9
            LQVL QKAS
Sbjct: 3526 LQVLPQKAS 3534
>NP_671714
          Length = 3899

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQVLLQKAS 9
            LQVL QKAS
Sbjct: 3518 LQVLPQKAS 3526
>NP_116271
          Length = 399

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LQVLLQKA 8
           L+VLLQKA
Sbjct: 263 LEVLLQKA 270
>XP_006715890
          Length = 3860

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQVLLQKAS 9
            LQVL QKAS
Sbjct: 3479 LQVLPQKAS 3487
>XP_005250160
          Length = 3939

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQVLLQKAS 9
            LQVL QKAS
Sbjct: 3558 LQVLPQKAS 3566
>XP_005250159
          Length = 3952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQVLLQKAS 9
            LQVL QKAS
Sbjct: 3571 LQVLPQKAS 3579
>NP_001093322
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQVLL+K +
Sbjct: 340 LQVLLEKVA 348
>NP_001136093
          Length = 860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVLLQKAS 9
           +VLLQ+AS
Sbjct: 619 EVLLQRAS 626
>NP_004248
          Length = 860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVLLQKAS 9
           +VLLQ+AS
Sbjct: 619 EVLLQRAS 626
>XP_006712924
          Length = 819

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVLLQKAS 9
           +VLLQ+AS
Sbjct: 619 EVLLQRAS 626
>XP_006712923
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVLLQKAS 9
           +VLLQ+AS
Sbjct: 619 EVLLQRAS 626
>NP_001091846
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>NP_001010890
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>NP_001009611
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>NP_001139816
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>NP_001013425
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 341 LQILLEKVA 349
>NP_001035362
          Length = 1762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    VLLQKAS 9
            VL+QKAS
Sbjct: 1477 VLMQKAS 1483
>NP_940894
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LQVLLQKAS 9
          L +LL KAS
Sbjct: 49 LSILLSKAS 57
>NP_001008783
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLLQKAS 9
           VL+QKAS
Sbjct: 173 VLIQKAS 179
>NP_001231785
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LQVLLQKAS 9
          L +LL KAS
Sbjct: 37 LSILLSKAS 45
>XP_006726395
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 342 LQILLEKVA 350
>XP_005276181
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>XP_005276180
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>XP_005276179
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>XP_006725019
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>XP_006725018
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>XP_006711146
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>XP_006711145
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>XP_006711143
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 343 LQILLEKVA 351
>NP_001010889
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQVLLQKAS 9
           LQ+LL+K +
Sbjct: 341 LQILLEKVA 349
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.128    0.284 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 319,204
Number of extensions: 372
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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