Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_001275582                                                           16    5631
NP_004850                                                              16    5631
NP_001186329                                                           16    5631
NP_001186327                                                           16    5631
NP_001186326                                                           16    5631
NP_001186328                                                           16    5631
NP_036356                                                              16    5631
NP_079385                                                              16    5631
NP_001157207                                                           16    5631
XP_006725418                                                           16    5631
XP_006725417                                                           16    5631
XP_006725416                                                           16    5631
XP_006725415                                                           16    5631
XP_006725414                                                           16    5631
XP_005257754                                                           16    5631
XP_005257753                                                           16    5631
XP_006722172                                                           16    5631
XP_006722171                                                           16    5631
XP_006722170                                                           16    5631
XP_005257069                                                           16    5631
XP_006714291                                                           16    5631
XP_006714290                                                           16    5631
NP_065928                                                              16    7355
XP_005256527                                                           16    7355
NP_001122074                                                           15    9605
NP_005730                                                              15    9605
NP_056190                                                              15    9605
NP_955749                                                              15    9605
NP_003165                                                              15    9605
NP_068506                                                              15    9605
NP_002026                                                              15    9605
NP_775844                                                              15    9605
XP_005252903                                                           15    9605
XP_005266734                                                           15    9605
XP_006722496                                                           15    9605
XP_005254171                                                           15    9605
XP_006718238                                                           15    9605
XP_006718237                                                           15    9605
XP_006717559                                                           15    9605
XP_006717558                                                           15    9605
XP_006717557                                                           15    9605
XP_006717556                                                           15    9605
XP_005252630                                                           15    9605
XP_005252629                                                           15    9605
XP_005252628                                                           15    9605
XP_005252627                                                           15    9605
XP_005252626                                                           15    9605
XP_005252625                                                           15    9605
XP_005252624                                                           15    9605
XP_005252623                                                           15    9605
XP_005252622                                                           15    9605
XP_006717555                                                           15    9605
XP_005252621                                                           15    9605
NP_002922                                                              15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQTRLIETT 9
           L TRLIETT
Sbjct: 509 LPTRLIETT 517
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQTRLIETT 9
           L TRLIETT
Sbjct: 304 LPTRLIETT 312
>NP_001275582
          Length = 1679

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 584 LQTRLLE 590
>NP_004850
          Length = 1675

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 580 LQTRLLE 586
>NP_001186329
          Length = 1214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           LQT L+E T
Sbjct: 778 LQTELLENT 786
>NP_001186327
          Length = 1242

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           LQT L+E T
Sbjct: 806 LQTELLENT 814
>NP_001186326
          Length = 1286

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           LQT L+E T
Sbjct: 850 LQTELLENT 858
>NP_001186328
          Length = 1189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           LQT L+E T
Sbjct: 753 LQTELLENT 761
>NP_036356
          Length = 1258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           LQT L+E T
Sbjct: 822 LQTELLENT 830
>NP_079385
          Length = 770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 652 LQTRLLE 658
>NP_001157207
          Length = 970

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 852 LQTRLLE 858
>XP_006725418
          Length = 705

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 587 LQTRLLE 593
>XP_006725417
          Length = 725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 607 LQTRLLE 613
>XP_006725416
          Length = 808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 690 LQTRLLE 696
>XP_006725415
          Length = 990

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 872 LQTRLLE 878
>XP_006725414
          Length = 1034

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 916 LQTRLLE 922
>XP_005257754
          Length = 705

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 587 LQTRLLE 593
>XP_005257753
          Length = 707

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 589 LQTRLLE 595
>XP_006722172
          Length = 808

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 690 LQTRLLE 696
>XP_006722171
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 854 LQTRLLE 860
>XP_006722170
          Length = 1016

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 898 LQTRLLE 904
>XP_005257069
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL+E
Sbjct: 580 LQTRLLE 586
>XP_006714291
          Length = 1227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           LQT L+E T
Sbjct: 850 LQTELLENT 858
>XP_006714290
          Length = 1269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           LQT L+E T
Sbjct: 833 LQTELLENT 841
>NP_065928
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LQTRLIETT 9
            LQT  +ETT
Sbjct: 1255 LQTETMETT 1263
>XP_005256527
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LQTRLIETT 9
            LQT  +ETT
Sbjct: 1255 LQTETMETT 1263
>NP_001122074
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           L  RLI+TT
Sbjct: 164 LHCRLIDTT 172
>NP_005730
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           L  RLI+TT
Sbjct: 164 LHCRLIDTT 172
>NP_056190
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL++
Sbjct: 351 LQTRLVD 357
>NP_955749
          Length = 884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LQTRLIE 7
           LQTRL++
Sbjct: 351 LQTRLVD 357
>NP_003165
          Length = 1788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1028 VQTRLVE 1034
>NP_068506
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1454 VQTRLVE 1460
>NP_002026
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           L+TRLI  T
Sbjct: 233 LETRLISET 241
>NP_775844
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQTRLIETT 9
           L+ RL++TT
Sbjct: 138 LEERLLQTT 146
>XP_005252903
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQTRLIETT 9
           L+ RL++TT
Sbjct: 211 LEERLLQTT 219
>XP_005266734
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           L+TRLI  T
Sbjct: 233 LETRLISET 241
>XP_006722496
          Length = 303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           L+TRLI  T
Sbjct: 204 LETRLISET 212
>XP_005254171
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQTRLIETT 9
           L  RLI+TT
Sbjct: 164 LHCRLIDTT 172
>XP_006718238
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQTRLIETT 9
           L+ RL++TT
Sbjct: 153 LEERLLQTT 161
>XP_006718237
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQTRLIETT 9
           L+ RL++TT
Sbjct: 211 LEERLLQTT 219
>XP_006717559
          Length = 1866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1106 VQTRLVE 1112
>XP_006717558
          Length = 1908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1148 VQTRLVE 1154
>XP_006717557
          Length = 1940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1180 VQTRLVE 1186
>XP_006717556
          Length = 2024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1264 VQTRLVE 1270
>XP_005252630
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1496 VQTRLVE 1502
>XP_005252629
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1496 VQTRLVE 1502
>XP_005252628
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1496 VQTRLVE 1502
>XP_005252627
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1496 VQTRLVE 1502
>XP_005252626
          Length = 2260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1500 VQTRLVE 1506
>XP_005252625
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1517 VQTRLVE 1523
>XP_005252624
          Length = 2292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1532 VQTRLVE 1538
>XP_005252623
          Length = 2302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1542 VQTRLVE 1548
>XP_005252622
          Length = 2308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1548 VQTRLVE 1554
>XP_006717555
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1568 VQTRLVE 1574
>XP_005252621
          Length = 2334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LQTRLIE 7
            +QTRL+E
Sbjct: 1574 VQTRLVE 1580
>NP_002922
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QTRLIETT 9
           QTR ++TT
Sbjct: 280 QTRYVKTT 287
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.129    0.309 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 357,121
Number of extensions: 504
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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