Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1135
NP_671714                                                              18    1135
XP_006715890                                                           18    1135
XP_005250160                                                           18    1135
XP_005250159                                                           18    1135
NP_004524                                                              18    1935
XP_006720661                                                           18    1935
XP_006720660                                                           18    1935
NP_003259                                                              17    2528
XP_006711570                                                           17    2528
XP_006711569                                                           17    2528
XP_006711568                                                           17    2528
XP_005273300                                                           17    2528
XP_006711567                                                           17    2528
XP_006711566                                                           17    2528
XP_005273298                                                           17    2528
XP_005273299                                                           17    2528
NP_001935                                                              17    3301
NP_919299                                                              17    4312
NP_002542                                                              17    4312
XP_006719831                                                           17    4312
NP_775791                                                              17    4312
NP_689716                                                              16    5631
NP_003406                                                              16    7355
NP_694558                                                              16    7355
NP_001274270                                                           16    7355
NP_001159354                                                           16    7355
NP_001159353                                                           16    7355
NP_001078880                                                           16    7355
NP_001274269                                                           16    7355
NP_659502                                                              16    7355
NP_001230064                                                           16    7355
NP_065831                                                              16    7355
NP_056343                                                              16    7355
NP_001230065                                                           16    7355
XP_005256660                                                           16    7355
XP_005256659                                                           16    7355
XP_005256658                                                           16    7355
XP_005256656                                                           16    7355
XP_006721565                                                           16    7355
XP_006721564                                                           16    7355
XP_006721563                                                           16    7355
XP_005256655                                                           16    7355
XP_005256654                                                           16    7355
XP_006721562                                                           16    7355
XP_006718547                                                           16    7355
XP_005248298                                                           16    7355
NP_001138424                                                           16    7355
NP_006502                                                              16    7355
NP_001091980                                                           16    7355
NP_001181927                                                           15    9605
NP_055800                                                              15    9605
NP_057260                                                              15    9605
NP_057631                                                              15    9605
NP_001172003                                                           15    9605
NP_001171988                                                           15    9605
NP_078893                                                              15    9605
NP_569057                                                              15    9605
XP_006722421                                                           15    9605
XP_006720500                                                           15    9605
XP_005252265                                                           15    9605
XP_005252264                                                           15    9605
XP_006717348                                                           15    9605
XP_006717347                                                           15    9605
XP_006717346                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQQVFL ER
Sbjct: 3030 LQQVFLEER 3038
>NP_671714
          Length = 3899

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQQVFL ER
Sbjct: 3022 LQQVFLEER 3030
>XP_006715890
          Length = 3860

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQQVFL ER
Sbjct: 2983 LQQVFLEER 2991
>XP_005250160
          Length = 3939

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQQVFL ER
Sbjct: 3062 LQQVFLEER 3070
>XP_005250159
          Length = 3952

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQQVFL ER
Sbjct: 3075 LQQVFLEER 3083
>NP_004524
          Length = 1141

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QQVFLGER 9
           QQVF+G+R
Sbjct: 355 QQVFVGDR 362
>XP_006720661
          Length = 585

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           +QQ+FLGE
Sbjct: 510 MQQLFLGE 517
>XP_006720660
          Length = 594

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           +QQ+FLGE
Sbjct: 510 MQQLFLGE 517
>NP_003259
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>XP_006711570
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>XP_006711569
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>XP_006711568
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>XP_005273300
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>XP_006711567
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>XP_006711566
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>XP_005273298
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>XP_005273299
          Length = 858

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LQQVFLGE 8
           L+Q+FLGE
Sbjct: 475 LEQLFLGE 482
>NP_001935
          Length = 999

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QQVFLGE 8
           QQ+F+GE
Sbjct: 159 QQIFMGE 165
>NP_919299
          Length = 498

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQVFLGER 9
           + VFLGER
Sbjct: 370 EPVFLGER 377
>NP_002542
          Length = 321

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           L Q+FLG R
Sbjct: 310 LWQIFLGRR 318
>XP_006719831
          Length = 479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQVFLGER 9
           + VFLGER
Sbjct: 351 EPVFLGER 358
>NP_775791
          Length = 152

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LQQVFLGER 9
          L+Q FLG R
Sbjct: 45 LRQAFLGSR 53
>NP_689716
          Length = 1052

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           L +VFLG R
Sbjct: 610 LYEVFLGNR 618
>NP_003406
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QQVFLGER 9
           QQ+++GE+
Sbjct: 267 QQMYMGEK 274
>NP_694558
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LQQVFLGE 8
           L +VF+GE
Sbjct: 112 LNEVFIGE 119
>NP_001274270
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LQQVFLGE 8
           L +VF+GE
Sbjct: 112 LNEVFIGE 119
>NP_001159354
          Length = 864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QQVFLGER 9
           QQ+++GE+
Sbjct: 184 QQMYMGEK 191
>NP_001159353
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QQVFLGER 9
           QQ+++GE+
Sbjct: 267 QQMYMGEK 274
>NP_001078880
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LQQVFLGE 8
           L +VF+GE
Sbjct: 275 LNEVFIGE 282
>NP_001274269
          Length = 279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LQQVFLGE 8
           L +VF+GE
Sbjct: 112 LNEVFIGE 119
>NP_659502
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VFLGER 9
           +FLGER
Sbjct: 214 IFLGER 219
>NP_001230064
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VFLGER 9
           +FLGER
Sbjct: 151 IFLGER 156
>NP_065831
          Length = 1392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           LQQ+ LG R
Sbjct: 156 LQQLHLGNR 164
>NP_056343
          Length = 350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 135 IPSVFIGER 143
>NP_001230065
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VFLGER 9
           +FLGER
Sbjct: 107 IFLGER 112
>XP_005256660
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 100 IPSVFIGER 108
>XP_005256659
          Length = 339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 100 IPSVFIGER 108
>XP_005256658
          Length = 339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 100 IPSVFIGER 108
>XP_005256656
          Length = 350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 135 IPSVFIGER 143
>XP_006721565
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 135 IPSVFIGER 143
>XP_006721564
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 135 IPSVFIGER 143
>XP_006721563
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 135 IPSVFIGER 143
>XP_005256655
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 135 IPSVFIGER 143
>XP_005256654
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 135 IPSVFIGER 143
>XP_006721562
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQQVFLGER 9
           +  VF+GER
Sbjct: 135 IPSVFIGER 143
>XP_006718547
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VFLGER 9
           +FLGER
Sbjct: 190 IFLGER 195
>XP_005248298
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LQQVFLGE 8
           L +VF+GE
Sbjct: 275 LNEVFIGE 282
>NP_001138424
          Length = 2172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QQVFLGE 8
            Q+VF+GE
Sbjct: 1614 QEVFVGE 1620
>NP_006502
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QVFLGER 9
           Q+FLGE+
Sbjct: 144 QMFLGEK 150
>NP_001091980
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VFLGER 9
           +FLGER
Sbjct: 190 IFLGER 195
>NP_001181927
          Length = 1710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LQQVFLG 7
           LQQ FLG
Sbjct: 221 LQQQFLG 227
>NP_055800
          Length = 1654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LQQVFLG 7
           LQQ FLG
Sbjct: 221 LQQQFLG 227
>NP_057260
          Length = 362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QQVFLGE 8
          Q+VFLG+
Sbjct: 79 QEVFLGK 85
>NP_057631
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QQVFLGE 8
          Q+VFLG+
Sbjct: 79 QEVFLGK 85
>NP_001172003
          Length = 1259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LQQVFLGER 9
           LQ+++ GE+
Sbjct: 956 LQEIYKGEK 964
>NP_001171988
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQ+++ GE+
Sbjct: 1192 LQEIYKGEK 1200
>NP_078893
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQ+++ GE+
Sbjct: 1192 LQEIYKGEK 1200
>NP_569057
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQQVFL 6
           LQQVFL
Sbjct: 244 LQQVFL 249
>XP_006722421
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQQVFL 6
           LQQVFL
Sbjct: 244 LQQVFL 249
>XP_006720500
          Length = 1710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LQQVFLG 7
           LQQ FLG
Sbjct: 221 LQQQFLG 227
>XP_005252265
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQ+++ GE+
Sbjct: 1192 LQEIYKGEK 1200
>XP_005252264
          Length = 1478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQ+++ GE+
Sbjct: 1192 LQEIYKGEK 1200
>XP_006717348
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQ+++ GE+
Sbjct: 1192 LQEIYKGEK 1200
>XP_006717347
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQ+++ GE+
Sbjct: 1192 LQEIYKGEK 1200
>XP_006717346
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LQQVFLGER 9
            LQ+++ GE+
Sbjct: 1192 LQEIYKGEK 1200
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.150    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 539,873
Number of extensions: 1085
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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