Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     299
NP_001075109                                                           20     299
NP_000375                                                              16    5631
NP_001175                                                              16    5631
NP_079173                                                              16    5631
NP_001259041                                                           16    5631
NP_001259040                                                           16    5631
NP_001259039                                                           16    5631
NP_001259038                                                           16    5631
NP_001259035                                                           16    5631
NP_001259042                                                           16    5631
XP_005245551                                                           16    5631
XP_006711616                                                           16    5631
XP_006711615                                                           16    5631
XP_006711612                                                           16    5631
XP_006711611                                                           16    5631
XP_005245548                                                           16    5631
XP_006711610                                                           16    5631
XP_006711609                                                           16    5631
XP_006711608                                                           16    5631
XP_006711607                                                           16    5631
XP_006711606                                                           16    5631
XP_006711605                                                           16    5631
NP_001274732                                                           16    7355
NP_115703                                                              16    7355
NP_932160                                                              16    7355
NP_001274733                                                           16    7355
NP_932161                                                              16    7355
NP_932163                                                              16    7355
NP_057736                                                              16    7355
XP_006718089                                                           16    7355
XP_006718088                                                           16    7355
XP_006718087                                                           16    7355
XP_006718086                                                           16    7355
XP_006718085                                                           16    7355
XP_006718084                                                           16    7355
NP_001182036                                                           15    9605
NP_112218                                                              15    9605
NP_001182035                                                           15    9605
NP_001017388                                                           15    9605
NP_001182037                                                           15    9605
XP_006714095                                                           15    9605
XP_006714094                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LQLRTYSIV 9
            LQLRTYS+V
Sbjct: 3786 LQLRTYSVV 3794
>NP_001075109
          Length = 4097

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LQLRTYSIV 9
            LQLRTYS+V
Sbjct: 3786 LQLRTYSVV 3794
>NP_000375
          Length = 4563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LQLRTYSIV 9
            LQL+ YS+V
Sbjct: 1786 LQLQPYSLV 1794
>NP_001175
          Length = 2644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LQLRTYSIV 9
            L +RTY+++
Sbjct: 2360 LHIRTYAVI 2368
>NP_079173
          Length = 351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 223 LQLGTYSLL 231
>NP_001259041
          Length = 211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQLRTYSIV 9
          LQL TYS++
Sbjct: 83 LQLGTYSLL 91
>NP_001259040
          Length = 211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQLRTYSIV 9
          LQL TYS++
Sbjct: 83 LQLGTYSLL 91
>NP_001259039
          Length = 211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQLRTYSIV 9
          LQL TYS++
Sbjct: 83 LQLGTYSLL 91
>NP_001259038
          Length = 211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQLRTYSIV 9
          LQL TYS++
Sbjct: 83 LQLGTYSLL 91
>NP_001259035
          Length = 283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 155 LQLGTYSLL 163
>NP_001259042
          Length = 211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQLRTYSIV 9
          LQL TYS++
Sbjct: 83 LQLGTYSLL 91
>XP_005245551
          Length = 211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQLRTYSIV 9
          LQL TYS++
Sbjct: 83 LQLGTYSLL 91
>XP_006711616
          Length = 346

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 218 LQLGTYSLL 226
>XP_006711615
          Length = 346

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 218 LQLGTYSLL 226
>XP_006711612
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 246 LQLGTYSLL 254
>XP_006711611
          Length = 433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 305 LQLGTYSLL 313
>XP_005245548
          Length = 454

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 326 LQLGTYSLL 334
>XP_006711610
          Length = 457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 329 LQLGTYSLL 337
>XP_006711609
          Length = 457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 329 LQLGTYSLL 337
>XP_006711608
          Length = 482

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 354 LQLGTYSLL 362
>XP_006711607
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 357 LQLGTYSLL 365
>XP_006711606
          Length = 506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 378 LQLGTYSLL 386
>XP_006711605
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQLRTYSIV 9
           LQL TYS++
Sbjct: 423 LQLGTYSLL 431
>NP_001274732
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_115703
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_932160
          Length = 361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_001274733
          Length = 307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_932161
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_932163
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_057736
          Length = 848

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LQLRTYSI 8
          L+LR+YS+
Sbjct: 26 LELRSYSL 33
>XP_006718089
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718088
          Length = 345

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718087
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718086
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718085
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>XP_006718084
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQLRTYSI 8
           L LRTYS+
Sbjct: 105 LILRTYSV 112
>NP_001182036
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQLRTYSIV 9
           +QL TYS V
Sbjct: 534 IQLETYSEV 542
>NP_112218
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQLRTYSIV 9
           +QL TYS V
Sbjct: 534 IQLETYSEV 542
>NP_001182035
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQLRTYSIV 9
           +QL TYS V
Sbjct: 534 IQLETYSEV 542
>NP_001017388
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQLRTYSIV 9
           +QL TYS V
Sbjct: 534 IQLETYSEV 542
>NP_001182037
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQLRTYSIV 9
           +QL TYS V
Sbjct: 520 IQLETYSEV 528
>XP_006714095
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQLRTYSIV 9
           +QL TYS V
Sbjct: 520 IQLETYSEV 528
>XP_006714094
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQLRTYSIV 9
           +QL TYS V
Sbjct: 520 IQLETYSEV 528
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.142    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 439,804
Number of extensions: 582
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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