Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              18    1135
NP_001091680                                                           18    1135
NP_001091679                                                           18    1135
XP_006713048                                                           18    1135
XP_006713047                                                           18    1135
XP_006713046                                                           18    1135
XP_005264943                                                           18    1135
NP_002221                                                              18    1935
NP_068831                                                              18    1935
XP_006721941                                                           18    1935
XP_006721940                                                           18    1935
XP_006721939                                                           18    1935
XP_006721938                                                           18    1935
XP_006721937                                                           18    1935
XP_006721936                                                           18    1935
XP_006721935                                                           18    1935
XP_006721934                                                           18    1935
XP_005257370                                                           18    1935
NP_115948                                                              17    3301
NP_036222                                                              17    4312
XP_006710603                                                           17    4312
XP_006710602                                                           17    4312
XP_006710601                                                           17    4312
XP_006710600                                                           17    4312
XP_005270757                                                           17    4312
XP_006710599                                                           17    4312
XP_006710598                                                           17    4312
XP_006710597                                                           17    4312
XP_006710596                                                           17    4312
XP_006710595                                                           17    4312
XP_006710594                                                           17    4312
XP_006710593                                                           17    4312
XP_006710592                                                           17    4312
XP_006710591                                                           17    4312
XP_006710590                                                           17    4312
XP_006710589                                                           17    4312
XP_006710588                                                           17    4312
XP_006710587                                                           17    4312
XP_006710586                                                           17    4312
XP_006710585                                                           17    4312
XP_005270755                                                           17    4312
XP_006710584                                                           17    4312
XP_005270754                                                           17    4312
XP_005270753                                                           17    4312
XP_006710583                                                           17    4312
XP_005270752                                                           17    4312
XP_006710582                                                           17    4312
XP_005270751                                                           17    4312
NP_005090                                                              16    7355
NP_848649                                                              16    7355
XP_006713675                                                           16    7355
XP_005247475                                                           16    7355
XP_005247474                                                           16    7355
NP_997290                                                              16    7355
NP_001315                                                              16    7355
NP_001028693                                                           16    7355
NP_001028694                                                           16    7355
NP_000409                                                              15    9605
NP_061985                                                              15    9605
NP_078853                                                              15    9605
NP_006609                                                              15    9605
NP_001244335                                                           15    9605
NP_057204                                                              15    9605
NP_899196                                                              15    9605
NP_004506                                                              15    9605
NP_001254738                                                           15    9605
XP_006722681                                                           15    9605
XP_006722680                                                           15    9605
XP_006722679                                                           15    9605
XP_005255366                                                           15    9605
XP_005255362                                                           15    9605
>NP_001895
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQILA GNQ
Sbjct: 301 LQILAYGNQ 309
>NP_001091680
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQILA GNQ
Sbjct: 301 LQILAYGNQ 309
>NP_001091679
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQILA GNQ
Sbjct: 301 LQILAYGNQ 309
>XP_006713048
          Length = 720

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQILA GNQ
Sbjct: 301 LQILAYGNQ 309
>XP_006713047
          Length = 774

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQILA GNQ
Sbjct: 294 LQILAYGNQ 302
>XP_006713046
          Length = 774

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQILA GNQ
Sbjct: 294 LQILAYGNQ 302
>XP_005264943
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQILA GNQ
Sbjct: 301 LQILAYGNQ 309
>NP_002221
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 292 LQLLAYGNQ 300
>NP_068831
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 292 LQLLAYGNQ 300
>XP_006721941
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 292 LQLLAYGNQ 300
>XP_006721940
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 292 LQLLAYGNQ 300
>XP_006721939
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 292 LQLLAYGNQ 300
>XP_006721938
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 292 LQLLAYGNQ 300
>XP_006721937
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 292 LQLLAYGNQ 300
>XP_006721936
          Length = 745

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 292 LQLLAYGNQ 300
>XP_006721935
          Length = 762

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 309 LQLLAYGNQ 317
>XP_006721934
          Length = 783

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 330 LQLLAYGNQ 338
>XP_005257370
          Length = 783

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ+LA GNQ
Sbjct: 330 LQLLAYGNQ 338
>NP_115948
          Length = 673

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQILASGNQ 9
           LQ+L  GNQ
Sbjct: 374 LQVLEDGNQ 382
>NP_036222
          Length = 5430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 2175 RMLASGNQ 2182
>XP_006710603
          Length = 5324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 2175 RMLASGNQ 2182
>XP_006710602
          Length = 7391

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4242 RMLASGNQ 4249
>XP_006710601
          Length = 4720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_006710600
          Length = 5384

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 2175 RMLASGNQ 2182
>XP_005270757
          Length = 5460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 2335 RMLASGNQ 2342
>XP_006710599
          Length = 5656

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 2335 RMLASGNQ 2342
>XP_006710598
          Length = 7553

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4232 RMLASGNQ 4239
>XP_006710597
          Length = 7451

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4242 RMLASGNQ 4249
>XP_006710596
          Length = 7512

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4191 RMLASGNQ 4198
>XP_006710595
          Length = 7526

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4205 RMLASGNQ 4212
>XP_006710594
          Length = 7528

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4207 RMLASGNQ 4214
>XP_006710593
          Length = 7539

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4218 RMLASGNQ 4225
>XP_006710592
          Length = 7544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4223 RMLASGNQ 4230
>XP_006710591
          Length = 7558

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4237 RMLASGNQ 4244
>XP_006710590
          Length = 7563

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4242 RMLASGNQ 4249
>XP_006710589
          Length = 7595

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4274 RMLASGNQ 4281
>XP_006710588
          Length = 7614

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_006710587
          Length = 7645

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4324 RMLASGNQ 4331
>XP_006710586
          Length = 7645

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_006710585
          Length = 7657

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_005270755
          Length = 7663

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_006710584
          Length = 7686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_005270754
          Length = 7694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_005270753
          Length = 7700

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_006710583
          Length = 7702

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_005270752
          Length = 7717

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_006710582
          Length = 7720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>XP_005270751
          Length = 7723

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QILASGNQ 9
            ++LASGNQ
Sbjct: 4402 RMLASGNQ 4409
>NP_005090
          Length = 837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LQILASGN 8
           LQ+L +GN
Sbjct: 783 LQVLVAGN 790
>NP_848649
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LQILASGN 8
           LQI A GN
Sbjct: 414 LQIFAKGN 421
>XP_006713675
          Length = 681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LQILASGN 8
           LQI A GN
Sbjct: 434 LQIFAKGN 441
>XP_005247475
          Length = 699

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LQILASGN 8
           LQI A GN
Sbjct: 452 LQIFAKGN 459
>XP_005247474
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LQILASGN 8
           LQI A GN
Sbjct: 455 LQIFAKGN 462
>NP_997290
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQILASGNQ 9
           LQ++ SG+Q
Sbjct: 224 LQLIGSGHQ 232
>NP_001315
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QILASGNQ 9
           QILASG++
Sbjct: 186 QILASGSR 193
>NP_001028693
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QILASGNQ 9
           QILASG++
Sbjct: 186 QILASGSR 193
>NP_001028694
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QILASGNQ 9
           QILASG++
Sbjct: 186 QILASGSR 193
>NP_000409
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LQILASGN 8
          LQ+ +SGN
Sbjct: 18 LQVASSGN 25
>NP_061985
          Length = 2146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QILASGN 8
            ++LASGN
Sbjct: 1329 KVLASGN 1335
>NP_078853
          Length = 1288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QILASGNQ 9
           Q+L SG+Q
Sbjct: 928 QVLVSGHQ 935
>NP_006609
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QILASGN 8
            Q+L+SGN
Sbjct: 1268 QLLSSGN 1274
>NP_001244335
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LQILASGN 8
          LQ+ +SGN
Sbjct: 18 LQVASSGN 25
>NP_057204
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILASGNQ 9
           +LASGN+
Sbjct: 614 VLASGNR 620
>NP_899196
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILASGNQ 9
           +LASGN+
Sbjct: 614 VLASGNR 620
>NP_004506
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQILASG 7
           LQILA+G
Sbjct: 272 LQILAAG 278
>NP_001254738
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQILASG 7
           LQILA+G
Sbjct: 234 LQILAAG 240
>XP_006722681
          Length = 1365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QILASGN 8
           ++LASGN
Sbjct: 548 KVLASGN 554
>XP_006722680
          Length = 1636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QILASGN 8
            ++LASGN
Sbjct: 1329 KVLASGN 1335
>XP_006722679
          Length = 2128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QILASGN 8
            ++LASGN
Sbjct: 1329 KVLASGN 1335
>XP_005255366
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LQILASGN 8
          LQ+ +SGN
Sbjct: 78 LQVASSGN 85
>XP_005255362
          Length = 885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LQILASGN 8
          LQ+ +SGN
Sbjct: 78 LQVASSGN 85
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.129    0.319 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 532,679
Number of extensions: 906
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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