Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1935
NP_001185763                                                           18    1935
NP_055459                                                              18    1935
XP_006726410                                                           18    1935
XP_006711719                                                           18    1935
XP_006711718                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
XP_006711164                                                           18    1935
XP_006710143                                                           18    1935
XP_006710142                                                           18    1935
XP_006710141                                                           18    1935
NP_001276976                                                           17    3301
NP_001276975                                                           17    3301
XP_006724141                                                           17    3301
NP_001164269                                                           17    3301
NP_006452                                                              17    4312
NP_620706                                                              16    5631
NP_003066                                                              16    5631
NP_001123892                                                           16    5631
NP_003065                                                              16    5631
XP_005256085                                                           16    5631
XP_005256083                                                           16    5631
XP_005256082                                                           16    5631
XP_005269161                                                           16    5631
XP_005269160                                                           16    5631
XP_005269159                                                           16    5631
XP_005269158                                                           16    5631
NP_060766                                                              16    5631
NP_001155047                                                           16    5631
NP_689994                                                              16    7355
XP_006725377                                                           16    7355
XP_006725375                                                           16    7355
XP_005258014                                                           16    7355
XP_005258013                                                           16    7355
XP_005258012                                                           16    7355
XP_006721865                                                           16    7355
XP_006721863                                                           16    7355
XP_005278292                                                           16    7355
XP_005278291                                                           16    7355
XP_005278290                                                           16    7355
NP_079221                                                              15    9605
NP_005465                                                              15    9605
NP_001015053                                                           15    9605
XP_006721692                                                           15    9605
XP_005256964                                                           15    9605
XP_005256963                                                           15    9605
XP_005256962                                                           15    9605
XP_005256961                                                           15    9605
XP_005252270                                                           15    9605
XP_005252268                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1186 LQEKLLLSE 1194
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1230 LQEKLLLSE 1238
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1230 LQEKLLLSE 1238
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1033 LQEKLLLSE 1041
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1186 LQEKLLLSE 1194
>XP_006711718
          Length = 1436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQE LLLSE
Sbjct: 237 LQEKLLLSE 245
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1186 LQEKLLLSE 1194
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1296 LQEKLLLSE 1304
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1230 LQEKLLLSE 1238
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1230 LQEKLLLSE 1238
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1233 LQEKLLLSE 1241
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1283 LQEKLLLSE 1291
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1296 LQEKLLLSE 1304
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1296 LQEKLLLSE 1304
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1393 LQEKLLLSE 1401
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQETLLLSE 9
            LQE LLLSE
Sbjct: 1033 LQEKLLLSE 1041
>XP_006710143
          Length = 562

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LQETLLLSE 9
          LQE LLLSE
Sbjct: 72 LQEKLLLSE 80
>XP_006710142
          Length = 671

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQE LLLSE
Sbjct: 182 LQEKLLLSE 190
>XP_006710141
          Length = 672

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQE LLLSE
Sbjct: 182 LQEKLLLSE 190
>NP_001276976
          Length = 1464

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQE +LLSE
Sbjct: 210 LQEEILLSE 218
>NP_001276975
          Length = 1300

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LQETLLLSE 9
          LQE +LLSE
Sbjct: 47 LQEEILLSE 55
>XP_006724141
          Length = 1426

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQE +LLSE
Sbjct: 172 LQEEILLSE 180
>NP_001164269
          Length = 579

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           L+ETLLL E
Sbjct: 548 LEETLLLHE 556
>NP_006452
          Length = 1193

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QETLLLS 8
           QETLLLS
Sbjct: 898 QETLLLS 904
>NP_620706
          Length = 1130

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QETLLLSE 9
           QETLLL E
Sbjct: 635 QETLLLLE 642
>NP_003066
          Length = 1214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QETLLLSE 9
           QETLLL E
Sbjct: 604 QETLLLLE 611
>NP_001123892
          Length = 1152

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QETLLLSE 9
           QETLLL E
Sbjct: 635 QETLLLLE 642
>NP_003065
          Length = 1105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QETLLLSE 9
           QETLLL E
Sbjct: 626 QETLLLLE 633
>XP_005256085
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           L+E L+LSE
Sbjct: 445 LEENLILSE 453
>XP_005256083
          Length = 607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           L+E L+LSE
Sbjct: 466 LEENLILSE 474
>XP_005256082
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           L+E L+LSE
Sbjct: 613 LEENLILSE 621
>XP_005269161
          Length = 1151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QETLLLSE 9
           QETLLL E
Sbjct: 634 QETLLLLE 641
>XP_005269160
          Length = 1213

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QETLLLSE 9
           QETLLL E
Sbjct: 603 QETLLLLE 610
>XP_005269159
          Length = 1244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QETLLLSE 9
           QETLLL E
Sbjct: 634 QETLLLLE 641
>XP_005269158
          Length = 1245

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QETLLLSE 9
           QETLLL E
Sbjct: 635 QETLLLLE 642
>NP_060766
          Length = 754

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           L+E L+LSE
Sbjct: 613 LEENLILSE 621
>NP_001155047
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           L+E L+LSE
Sbjct: 492 LEENLILSE 500
>NP_689994
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 456 LQETLIL 462
>XP_006725377
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 274 LQETLIL 280
>XP_006725375
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 307 LQETLIL 313
>XP_005258014
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 382 LQETLIL 388
>XP_005258013
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 416 LQETLIL 422
>XP_005258012
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 422 LQETLIL 428
>XP_006721865
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 274 LQETLIL 280
>XP_006721863
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 307 LQETLIL 313
>XP_005278292
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 382 LQETLIL 388
>XP_005278291
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 416 LQETLIL 422
>XP_005278290
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LQETLLL 7
           LQETL+L
Sbjct: 422 LQETLIL 428
>NP_079221
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQETLLLSE 9
           L+E LLL E
Sbjct: 316 LEEALLLEE 324
>NP_005465
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQET LLS+
Sbjct: 718 LQETGLLSK 726
>NP_001015053
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQET LLS+
Sbjct: 719 LQETGLLSK 727
>XP_006721692
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQET LLS+
Sbjct: 677 LQETGLLSK 685
>XP_005256964
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQET LLS+
Sbjct: 714 LQETGLLSK 722
>XP_005256963
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQET LLS+
Sbjct: 718 LQETGLLSK 726
>XP_005256962
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQET LLS+
Sbjct: 718 LQETGLLSK 726
>XP_005256961
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LQETLLLSE 9
           LQET LLS+
Sbjct: 719 LQETGLLSK 727
>XP_005252270
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQETLLLSE 9
           L+E LLL E
Sbjct: 316 LEEALLLEE 324
>XP_005252268
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQETLLLSE 9
           L+E LLL E
Sbjct: 316 LEEALLLEE 324
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.128    0.285 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 459,106
Number of extensions: 698
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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