Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_056293                                                              18    1935
NP_115479                                                              18    1935
XP_005256357                                                           17    2528
XP_005256356                                                           17    2528
XP_005256355                                                           17    2528
XP_005256354                                                           17    2528
NP_055787                                                              17    2528
XP_005266741                                                           17    4312
XP_005266739                                                           17    4312
NP_114097                                                              17    4312
NP_001007103                                                           16    5631
NP_115814                                                              16    5631
NP_036466                                                              16    5631
NP_775735                                                              16    5631
NP_004923                                                              16    5631
XP_006722429                                                           16    5631
XP_006722428                                                           16    5631
XP_006722427                                                           16    5631
XP_006722426                                                           16    5631
XP_005258225                                                           16    5631
XP_006722425                                                           16    5631
XP_005258223                                                           16    5631
XP_005267218                                                           16    5631
XP_006715641                                                           16    5631
XP_006715640                                                           16    5631
XP_006715639                                                           16    5631
XP_006714538                                                           16    5631
NP_002903                                                              16    7355
NP_001273361                                                           16    7355
NP_001273360                                                           16    7355
NP_067636                                                              16    7355
NP_001265484                                                           16    7355
NP_001265483                                                           16    7355
NP_872619                                                              16    7355
NP_006348                                                              16    7355
XP_006715607                                                           16    7355
XP_006715606                                                           16    7355
XP_005246301                                                           16    7355
NP_115646                                                              15    9605
NP_002325                                                              15    9605
NP_001001974                                                           15    9605
NP_067635                                                              15    9605
NP_062540                                                              15    9605
NP_001182537                                                           15    9605
NP_001120717                                                           15    9605
NP_001120716                                                           15    9605
NP_006835                                                              15    9605
NP_006718                                                              15    9605
XP_006724135                                                           15    9605
XP_005259774                                                           15    9605
XP_006718294                                                           15    9605
XP_005252980                                                           15    9605
XP_005270078                                                           15    9605
XP_006717998                                                           15    9605
XP_005270077                                                           15    9605
XP_005270076                                                           15    9605
XP_005270075                                                           15    9605
XP_005270074                                                           15    9605
XP_005270073                                                           15    9605
XP_005252152                                                           15    9605
XP_005252153                                                           15    9605
XP_006717249                                                           15    9605
XP_006711023                                                           15    9605
>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQAVDQRDP 9
            LQAV QRDP
Sbjct: 2794 LQAVAQRDP 2802
>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LQAVDQRDP 9
            LQAV QRDP
Sbjct: 2794 LQAVAQRDP 2802
>NP_056293
          Length = 772

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LQAVDQRDP 9
           L+AVD+R+P
Sbjct: 455 LEAVDRRNP 463
>NP_115479
          Length = 840

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LQAVDQRDP 9
           L+AVD+R+P
Sbjct: 523 LEAVDRRNP 531
>XP_005256357
          Length = 481

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           LQAVD  DP
Sbjct: 292 LQAVDAGDP 300
>XP_005256356
          Length = 701

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           LQAVD  DP
Sbjct: 512 LQAVDAGDP 520
>XP_005256355
          Length = 708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           LQAVD  DP
Sbjct: 527 LQAVDAGDP 535
>XP_005256354
          Length = 716

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           LQAVD  DP
Sbjct: 527 LQAVDAGDP 535
>NP_055787
          Length = 676

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           LQAVD  DP
Sbjct: 527 LQAVDAGDP 535
>XP_005266741
          Length = 649

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           + AVDQ DP
Sbjct: 515 VSAVDQDDP 523
>XP_005266739
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           + AVDQ DP
Sbjct: 515 VSAVDQDDP 523
>NP_114097
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           + AVDQ DP
Sbjct: 515 VSAVDQDDP 523
>NP_001007103
          Length = 755

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 456 LEVVDKRNP 464
>NP_115814
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 481 LEVVDKRNP 489
>NP_036466
          Length = 2058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QAVDQRD 8
           QAVD RD
Sbjct: 393 QAVDSRD 399
>NP_775735
          Length = 623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 302 LEVVDKRNP 310
>NP_004923
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           L AVD+ DP
Sbjct: 509 LHAVDKDDP 517
>XP_006722429
          Length = 331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 302 LEVVDKRNP 310
>XP_006722428
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 302 LEVVDKRNP 310
>XP_006722427
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 302 LEVVDKRNP 310
>XP_006722426
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 215 LEVVDKRNP 223
>XP_005258225
          Length = 534

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 302 LEVVDKRNP 310
>XP_006722425
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 302 LEVVDKRNP 310
>XP_005258223
          Length = 614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 302 LEVVDKRNP 310
>XP_005267218
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 481 LEVVDKRNP 489
>XP_006715641
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 481 LEVVDKRNP 489
>XP_006715640
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 481 LEVVDKRNP 489
>XP_006715639
          Length = 815

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LQAVDQRDP 9
           L+ VD+R+P
Sbjct: 516 LEVVDKRNP 524
>XP_006714538
          Length = 2035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   QAVDQRD 8
           QAVD RD
Sbjct: 393 QAVDSRD 399
>NP_002903
          Length = 3130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    QAVDQRDP 9
            + +DQ+DP
Sbjct: 2841 ETLDQKDP 2848
>NP_001273361
          Length = 3052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    QAVDQRDP 9
            + +DQ+DP
Sbjct: 2763 ETLDQKDP 2770
>NP_001273360
          Length = 3052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    QAVDQRDP 9
            + +DQ+DP
Sbjct: 2763 ETLDQKDP 2770
>NP_067636
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQAVDQRD 8
           LQA DQ+D
Sbjct: 93  LQANDQKD 100
>NP_001265484
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5  DQRDP 9
          DQRDP
Sbjct: 23 DQRDP 27
>NP_001265483
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5  DQRDP 9
          DQRDP
Sbjct: 23 DQRDP 27
>NP_872619
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5  DQRDP 9
          DQRDP
Sbjct: 23 DQRDP 27
>NP_006348
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5  DQRDP 9
          DQRDP
Sbjct: 23 DQRDP 27
>XP_006715607
          Length = 3052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    QAVDQRDP 9
            + +DQ+DP
Sbjct: 2763 ETLDQKDP 2770
>XP_006715606
          Length = 3130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    QAVDQRDP 9
            + +DQ+DP
Sbjct: 2841 ETLDQKDP 2848
>XP_005246301
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5  DQRDP 9
          DQRDP
Sbjct: 23 DQRDP 27
>NP_115646
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LQAVDQRDP 9
           L  +DQ DP
Sbjct: 374 LHMIDQYDP 382
>NP_002325
          Length = 1905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LQAVDQRDP 9
            +QAVD+  P
Sbjct: 1299 MQAVDRAQP 1307
>NP_001001974
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>NP_067635
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>NP_062540
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LQAVDQRDP 9
           L  +DQ DP
Sbjct: 376 LHLIDQYDP 384
>NP_001182537
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>NP_001120717
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LQAVDQRDP 9
           L  +DQ DP
Sbjct: 376 LHLIDQYDP 384
>NP_001120716
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LQAVDQRDP 9
           L  +DQ DP
Sbjct: 376 LHLIDQYDP 384
>NP_006835
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQAVDQ 6
           LQAVDQ
Sbjct: 160 LQAVDQ 165
>NP_006718
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LQAVDQRDP 9
           + AVD+ DP
Sbjct: 510 ISAVDKDDP 518
>XP_006724135
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QAVDQRDP 9
           +A+DQR P
Sbjct: 145 RALDQRGP 152
>XP_005259774
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LQAVDQ 6
           LQAVDQ
Sbjct: 160 LQAVDQ 165
>XP_006718294
          Length = 1808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LQAVDQRDP 9
            +QAVD+  P
Sbjct: 1299 MQAVDRAQP 1307
>XP_005252980
          Length = 1809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    LQAVDQRDP 9
            +QAVD+  P
Sbjct: 1299 MQAVDRAQP 1307
>XP_005270078
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_006717998
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270077
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270076
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270075
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270074
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005270073
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LQAVDQRD 8
          LQA DQ+D
Sbjct: 92 LQANDQQD 99
>XP_005252152
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LQAVDQRDP 9
           L  +DQ DP
Sbjct: 376 LHLIDQYDP 384
>XP_005252153
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LQAVDQRDP 9
           L  +DQ DP
Sbjct: 376 LHLIDQYDP 384
>XP_006717249
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LQAVDQRDP 9
           L  +DQ DP
Sbjct: 376 LHLIDQYDP 384
>XP_006711023
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LQAVDQRDP 9
           L  +DQ DP
Sbjct: 379 LHMIDQYDP 387
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.134    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 546,307
Number of extensions: 889
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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