Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1135
NP_671714                                                              18    1135
NP_001265003                                                           18    1135
NP_000084                                                              18    1135
XP_006715890                                                           18    1135
XP_005250160                                                           18    1135
XP_005250159                                                           18    1135
NP_001161795                                                           17    3301
NP_660316                                                              17    3301
NP_001161796                                                           17    3301
NP_001161794                                                           17    3301
XP_005257133                                                           17    3301
XP_005257132                                                           17    3301
XP_006721785                                                           17    3301
XP_006721784                                                           17    3301
NP_001186064                                                           17    4312
NP_597841                                                              17    4312
NP_004171                                                              17    4312
XP_005246268                                                           17    4312
XP_005246267                                                           17    4312
XP_005246265                                                           17    4312
XP_005246264                                                           17    4312
XP_005246263                                                           17    4312
NP_001193928                                                           16    5631
NP_009105                                                              16    5631
XP_005253886                                                           16    5631
XP_006719269                                                           16    5631
NP_001153505                                                           15    9605
NP_056506                                                              15    9605
NP_003073                                                              15    9605
>NP_005742
          Length = 3907

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQASETRRN 9
           LQASET RN
Sbjct: 245 LQASETLRN 253
>NP_671714
          Length = 3899

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQASETRRN 9
           LQASET RN
Sbjct: 245 LQASETLRN 253
>NP_001265003
          Length = 1838

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LQASETRRN 9
            +QAS TRRN
Sbjct: 1578 IQASRTRRN 1586
>NP_000084
          Length = 1838

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LQASETRRN 9
            +QAS TRRN
Sbjct: 1578 IQASRTRRN 1586
>XP_006715890
          Length = 3860

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQASETRRN 9
           LQASET RN
Sbjct: 245 LQASETLRN 253
>XP_005250160
          Length = 3939

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQASETRRN 9
           LQASET RN
Sbjct: 245 LQASETLRN 253
>XP_005250159
          Length = 3952

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LQASETRRN 9
           LQASET RN
Sbjct: 245 LQASETLRN 253
>NP_001161795
          Length = 273

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QASETRRN 9
           QA+ET+RN
Sbjct: 246 QATETQRN 253
>NP_660316
          Length = 332

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QASETRRN 9
           QA+ET+RN
Sbjct: 280 QATETQRN 287
>NP_001161796
          Length = 233

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QASETRRN 9
           QA+ET+RN
Sbjct: 195 QATETQRN 202
>NP_001161794
          Length = 307

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QASETRRN 9
           QA+ET+RN
Sbjct: 280 QATETQRN 287
>XP_005257133
          Length = 287

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QASETRRN 9
           QA+ET+RN
Sbjct: 195 QATETQRN 202
>XP_005257132
          Length = 321

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QASETRRN 9
           QA+ET+RN
Sbjct: 229 QATETQRN 236
>XP_006721785
          Length = 338

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QASETRRN 9
           QA+ET+RN
Sbjct: 246 QATETQRN 253
>XP_006721784
          Length = 372

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QASETRRN 9
           QA+ET+RN
Sbjct: 280 QATETQRN 287
>NP_001186064
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQASETRRN 9
          L+ SETR+N
Sbjct: 79 LEDSETRKN 87
>NP_597841
          Length = 119

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQASETRRN 9
          L+ SETR+N
Sbjct: 79 LEDSETRKN 87
>NP_004171
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQASETRRN 9
          L+ SETR+N
Sbjct: 79 LEDSETRKN 87
>XP_005246268
          Length = 426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQASETRRN 9
          L+ SETR+N
Sbjct: 80 LEDSETRKN 88
>XP_005246267
          Length = 426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LQASETRRN 9
          L+ SETR+N
Sbjct: 80 LEDSETRKN 88
>XP_005246265
          Length = 484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQASETRRN 9
           L+ SETR+N
Sbjct: 138 LEDSETRKN 146
>XP_005246264
          Length = 532

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQASETRRN 9
           L+ SETR+N
Sbjct: 186 LEDSETRKN 194
>XP_005246263
          Length = 533

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LQASETRRN 9
           L+ SETR+N
Sbjct: 187 LEDSETRKN 195
>NP_001193928
          Length = 2069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LQASETRRN 9
           L+ASET+R+
Sbjct: 493 LKASETQRS 501
>NP_009105
          Length = 2027

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LQASETRRN 9
           L+ASET+R+
Sbjct: 493 LKASETQRS 501
>XP_005253886
          Length = 1545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LQASETRRN 9
          L+ASET+R+
Sbjct: 27 LKASETQRS 35
>XP_006719269
          Length = 2054

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LQASETRRN 9
           L+ASET+R+
Sbjct: 493 LKASETQRS 501
>NP_001153505
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    QASETR 7
            QASETR
Sbjct: 1255 QASETR 1260
>NP_056506
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LQASETRR 8
           LQAS TR+
Sbjct: 973 LQASRTRQ 980
>NP_003073
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LQASETRRN 9
           +QAS++RR+
Sbjct: 274 IQASKSRRH 282
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.112    0.266 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 306,774
Number of extensions: 203
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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