Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_659495                                                              17    3301
NP_056244                                                              17    3301
XP_005247374                                                           17    3301
XP_005247373                                                           17    3301
XP_005247372                                                           17    3301
XP_005247370                                                           17    3301
XP_005247369                                                           17    3301
XP_005247368                                                           17    3301
XP_005247367                                                           17    3301
XP_005247366                                                           17    3301
XP_006713639                                                           17    3301
XP_006713638                                                           17    3301
XP_005247365                                                           17    3301
XP_005247364                                                           17    3301
XP_005247363                                                           17    3301
XP_006713637                                                           17    3301
XP_006713636                                                           17    3301
XP_005247362                                                           17    3301
XP_005247360                                                           17    3301
XP_006713635                                                           17    3301
XP_006713634                                                           17    3301
XP_005247359                                                           17    3301
XP_006713633                                                           17    3301
XP_005247357                                                           17    3301
XP_005247356                                                           17    3301
XP_005247355                                                           17    3301
XP_005247354                                                           17    3301
XP_005247353                                                           17    3301
XP_005247352                                                           17    3301
XP_005247351                                                           17    3301
XP_005247350                                                           17    3301
XP_005247347                                                           17    3301
XP_005247346                                                           17    3301
XP_005247345                                                           17    3301
XP_005247344                                                           17    3301
XP_005247343                                                           17    3301
XP_005247342                                                           17    3301
XP_005247341                                                           17    3301
XP_005247340                                                           17    3301
XP_005247339                                                           17    3301
XP_006713631                                                           17    3301
XP_005247338                                                           17    3301
NP_055906                                                              17    4312
NP_001431                                                              17    4312
XP_006720146                                                           17    4312
XP_005267508                                                           17    4312
XP_006716365                                                           17    4312
NP_001119714                                                           16    5631
NP_001191114                                                           16    5631
NP_001136092                                                           16    5631
NP_057347                                                              16    5631
XP_006722827                                                           16    5631
XP_005259630                                                           16    5631
NP_001129670                                                           16    5631
NP_001129669                                                           16    5631
NP_001003841                                                           16    7355
NP_000134                                                              15    9605
NP_919290                                                              15    9605
NP_579875                                                              15    9605
NP_758847                                                              15    9605
NP_004479                                                              15    9605
NP_997527                                                              15    9605
NP_056356                                                              15    9605
XP_005246247                                                           15    9605
NP_473365                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LPRVTELA 8
           LPRVTELA
Sbjct: 911 LPRVTELA 918
>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LPRVTELA 8
           LPRVTELA
Sbjct: 911 LPRVTELA 918
>NP_659495
          Length = 211

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PRVTELAF 9
          PRVT+L F
Sbjct: 59 PRVTQLQF 66
>NP_056244
          Length = 1075

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LPRVTELA 8
           +PR TELA
Sbjct: 644 IPRTTELA 651
>XP_005247374
          Length = 1129

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LPRVTELA 8
           +PR TELA
Sbjct: 673 IPRTTELA 680
>XP_005247373
          Length = 1149

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LPRVTELA 8
           +PR TELA
Sbjct: 693 IPRTTELA 700
>XP_005247372
          Length = 1165

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LPRVTELA 8
           +PR TELA
Sbjct: 709 IPRTTELA 716
>XP_005247370
          Length = 1350

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LPRVTELA 8
           +PR TELA
Sbjct: 919 IPRTTELA 926
>XP_005247369
          Length = 1366

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LPRVTELA 8
           +PR TELA
Sbjct: 910 IPRTTELA 917
>XP_005247368
          Length = 1391

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LPRVTELA 8
           +PR TELA
Sbjct: 935 IPRTTELA 942
>XP_005247367
          Length = 1451

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 995  IPRTTELA 1002
>XP_005247366
          Length = 1495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1039 IPRTTELA 1046
>XP_006713639
          Length = 1579

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1123 IPRTTELA 1130
>XP_006713638
          Length = 1601

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1145 IPRTTELA 1152
>XP_005247365
          Length = 1607

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1151 IPRTTELA 1158
>XP_005247364
          Length = 1637

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1181 IPRTTELA 1188
>XP_005247363
          Length = 1657

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1201 IPRTTELA 1208
>XP_006713637
          Length = 1659

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1203 IPRTTELA 1210
>XP_006713636
          Length = 1673

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1217 IPRTTELA 1224
>XP_005247362
          Length = 1678

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1222 IPRTTELA 1229
>XP_005247360
          Length = 1706

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1250 IPRTTELA 1257
>XP_006713635
          Length = 1719

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1263 IPRTTELA 1270
>XP_006713634
          Length = 1721

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1265 IPRTTELA 1272
>XP_005247359
          Length = 1725

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1269 IPRTTELA 1276
>XP_006713633
          Length = 1731

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1275 IPRTTELA 1282
>XP_005247357
          Length = 1735

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1279 IPRTTELA 1286
>XP_005247356
          Length = 1744

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1288 IPRTTELA 1295
>XP_005247355
          Length = 1745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1289 IPRTTELA 1296
>XP_005247354
          Length = 1745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1289 IPRTTELA 1296
>XP_005247353
          Length = 1746

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1290 IPRTTELA 1297
>XP_005247352
          Length = 1747

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1291 IPRTTELA 1298
>XP_005247351
          Length = 1754

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1298 IPRTTELA 1305
>XP_005247350
          Length = 1757

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1301 IPRTTELA 1308
>XP_005247347
          Length = 1768

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1337 IPRTTELA 1344
>XP_005247346
          Length = 1768

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1312 IPRTTELA 1319
>XP_005247345
          Length = 1769

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1313 IPRTTELA 1320
>XP_005247344
          Length = 1771

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1315 IPRTTELA 1322
>XP_005247343
          Length = 1771

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1315 IPRTTELA 1322
>XP_005247342
          Length = 1773

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1317 IPRTTELA 1324
>XP_005247341
          Length = 1774

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1318 IPRTTELA 1325
>XP_005247340
          Length = 1777

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1321 IPRTTELA 1328
>XP_005247339
          Length = 1779

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1323 IPRTTELA 1330
>XP_006713631
          Length = 1789

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1333 IPRTTELA 1340
>XP_005247338
          Length = 1793

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LPRVTELA 8
            +PR TELA
Sbjct: 1337 IPRTTELA 1344
>NP_055906
          Length = 1720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LPRVTELAF 9
           LPR+TE  F
Sbjct: 578 LPRLTEQGF 586
>NP_001431
          Length = 919

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PRVTELAF 9
           PRVTE+ F
Sbjct: 488 PRVTEVHF 495
>XP_006720146
          Length = 1226

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LPRVTELAF 9
           LPR+TE  F
Sbjct: 578 LPRLTEQGF 586
>XP_005267508
          Length = 1773

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LPRVTELAF 9
           LPR+TE  F
Sbjct: 578 LPRLTEQGF 586
>XP_006716365
          Length = 919

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PRVTELAF 9
           PRVTE+ F
Sbjct: 488 PRVTEVHF 495
>NP_001119714
          Length = 426

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LPRVTE 6
           LPRVTE
Sbjct: 412 LPRVTE 417
>NP_001191114
          Length = 475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LPRVTE 6
           LPRVTE
Sbjct: 461 LPRVTE 466
>NP_001136092
          Length = 159

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LPRVTEL 7
           LP++TEL
Sbjct: 146 LPKITEL 152
>NP_057347
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LPRVTEL 7
          +PRVTE+
Sbjct: 21 MPRVTEM 27
>XP_006722827
          Length = 247

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LPRVTEL 7
          +PRVTE+
Sbjct: 21 MPRVTEM 27
>XP_005259630
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LPRVTEL 7
          +PRVTE+
Sbjct: 21 MPRVTEM 27
>NP_001129670
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LPRVTEL 7
          +PRVTE+
Sbjct: 21 MPRVTEM 27
>NP_001129669
          Length = 404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LPRVTEL 7
          +PRVTE+
Sbjct: 21 MPRVTEM 27
>NP_001003841
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PRVTELA 8
           P VTELA
Sbjct: 257 PNVTELA 263
>NP_000134
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LPRVTELA 8
           +PR+ ELA
Sbjct: 266 MPRIYELA 273
>NP_919290
          Length = 909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   PRVTELAF 9
           PR  +LAF
Sbjct: 849 PRAADLAF 856
>NP_579875
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PRVTELAF 9
          PR+ EL+F
Sbjct: 87 PRMCELSF 94
>NP_758847
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PRVTELAF 9
          PR+ EL+F
Sbjct: 87 PRMCELSF 94
>NP_004479
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LPRVTEL 7
           LPR+TE+
Sbjct: 410 LPRLTEV 416
>NP_997527
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LPRVTEL 7
           LPR+T+L
Sbjct: 207 LPRLTQL 213
>NP_056356
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LPRVTEL 7
           LPR+T+L
Sbjct: 210 LPRLTQL 216
>XP_005246247
          Length = 1417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    PRVTELAF 9
            PR+ +LAF
Sbjct: 1387 PRLLDLAF 1394
>NP_473365
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LPRVTELAF 9
           +P+ TEL F
Sbjct: 473 IPKETELPF 481
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.146    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 472,067
Number of extensions: 799
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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