Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155048                                                           18    1935
NP_056404                                                              18    1935
NP_001245348                                                           17    4312
NP_065980                                                              17    4312
NP_065904                                                              17    4312
NP_056493                                                              16    5631
NP_001123465                                                           16    5631
NP_872393                                                              16    5631
XP_006719869                                                           16    5631
XP_006719868                                                           16    5631
XP_005266409                                                           16    5631
XP_005266408                                                           16    5631
XP_005266407                                                           16    5631
XP_005266403                                                           16    5631
XP_006719867                                                           16    5631
XP_006719866                                                           16    5631
XP_005266405                                                           16    5631
XP_005266404                                                           16    5631
XP_006712515                                                           16    5631
XP_006712513                                                           16    5631
XP_006712512                                                           16    5631
XP_006712511                                                           16    5631
XP_006712510                                                           16    5631
XP_006712509                                                           16    5631
XP_005246533                                                           16    5631
XP_006712508                                                           16    5631
XP_005264664                                                           16    5631
XP_005264663                                                           16    5631
XP_005264662                                                           16    5631
NP_115895                                                              16    5631
NP_115893                                                              16    5631
NP_055330                                                              16    7355
NP_001186231                                                           16    7355
NP_001002796                                                           16    7355
NP_078993                                                              16    7355
NP_001186232                                                           16    7355
XP_005257998                                                           16    7355
XP_005257995                                                           16    7355
XP_005257994                                                           16    7355
XP_006719496                                                           16    7355
XP_006719495                                                           16    7355
XP_006719494                                                           16    7355
XP_006719493                                                           16    7355
XP_006719492                                                           16    7355
XP_005272148                                                           16    7355
XP_005272147                                                           16    7355
XP_006714755                                                           16    7355
XP_005272145                                                           16    7355
XP_005272144                                                           16    7355
XP_005272143                                                           16    7355
XP_005272142                                                           16    7355
XP_005272141                                                           16    7355
XP_005272140                                                           16    7355
XP_005272139                                                           16    7355
NP_001273                                                              16    7355
NP_001025177                                                           16    7355
NP_000892                                                              15    9605
NP_001159576                                                           15    9605
NP_112092                                                              15    9605
NP_849157                                                              15    9605
NP_663612                                                              15    9605
XP_006724281                                                           15    9605
XP_006724280                                                           15    9605
XP_006714285                                                           15    9605
XP_005263071                                                           15    9605
XP_006714159                                                           15    9605
XP_006714158                                                           15    9605
XP_006714157                                                           15    9605
>NP_001155048
          Length = 630

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LNTVGTTTA 9
           +NT+GT+T+
Sbjct: 229 INTIGTSTS 237
>NP_056404
          Length = 718

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LNTVGTTTA 9
           +NT+GT+T+
Sbjct: 229 INTIGTSTS 237
>NP_001245348
          Length = 640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NTVGTTTA 9
           N+VG TTA
Sbjct: 430 NSVGNTTA 437
>NP_065980
          Length = 640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NTVGTTTA 9
           N+VG TTA
Sbjct: 430 NSVGNTTA 437
>NP_065904
          Length = 622

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NTVGTTTA 9
           NT GT TA
Sbjct: 538 NTTGTVTA 545
>NP_056493
          Length = 2946

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1805 VTTVGATTA 1813
>NP_001123465
          Length = 718

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LNTVGT 6
           LNTVGT
Sbjct: 430 LNTVGT 435
>NP_872393
          Length = 3234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2916 ISTVGTSTS 2924
>XP_006719869
          Length = 2943

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1802 VTTVGATTA 1810
>XP_006719868
          Length = 2938

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1802 VTTVGATTA 1810
>XP_005266409
          Length = 1430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           + TVG TTA
Sbjct: 268 VTTVGATTA 276
>XP_005266408
          Length = 1934

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1805 VTTVGATTA 1813
>XP_005266407
          Length = 2641

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1479 VTTVGATTA 1487
>XP_005266403
          Length = 2941

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1805 VTTVGATTA 1813
>XP_006719867
          Length = 2961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1805 VTTVGATTA 1813
>XP_006719866
          Length = 2962

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1805 VTTVGATTA 1813
>XP_005266405
          Length = 2964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1802 VTTVGATTA 1810
>XP_005266404
          Length = 2967

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNTVGTTTA 9
            + TVG TTA
Sbjct: 1805 VTTVGATTA 1813
>XP_006712515
          Length = 3232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2914 ISTVGTSTS 2922
>XP_006712513
          Length = 3220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2883 ISTVGTSTS 2891
>XP_006712512
          Length = 3237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2919 ISTVGTSTS 2927
>XP_006712511
          Length = 3256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2919 ISTVGTSTS 2927
>XP_006712510
          Length = 3305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2987 ISTVGTSTS 2995
>XP_006712509
          Length = 3319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2982 ISTVGTSTS 2990
>XP_005246533
          Length = 3323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2986 ISTVGTSTS 2994
>XP_006712508
          Length = 3324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2987 ISTVGTSTS 2995
>XP_005264664
          Length = 572

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LNTVGT 6
           LNTVGT
Sbjct: 284 LNTVGT 289
>XP_005264663
          Length = 707

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LNTVGT 6
           LNTVGT
Sbjct: 430 LNTVGT 435
>XP_005264662
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LNTVGT 6
           LNTVGT
Sbjct: 430 LNTVGT 435
>NP_115895
          Length = 707

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LNTVGT 6
           LNTVGT
Sbjct: 430 LNTVGT 435
>NP_115893
          Length = 3258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LNTVGTTTA 9
            ++TVGT+T+
Sbjct: 2921 ISTVGTSTS 2929
>NP_055330
          Length = 540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           LNT G TT+
Sbjct: 302 LNTSGKTTS 310
>NP_001186231
          Length = 540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           LNT G TT+
Sbjct: 302 LNTSGKTTS 310
>NP_001002796
          Length = 778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 22 INTAGTSNA 30
>NP_078993
          Length = 999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           +NT GT+ A
Sbjct: 243 INTAGTSNA 251
>NP_001186232
          Length = 540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           LNT G TT+
Sbjct: 302 LNTSGKTTS 310
>XP_005257998
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGTTTA 9
           VGTTTA
Sbjct: 607 VGTTTA 612
>XP_005257995
          Length = 951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGTTTA 9
           VGTTTA
Sbjct: 607 VGTTTA 612
>XP_005257994
          Length = 951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGTTTA 9
           VGTTTA
Sbjct: 607 VGTTTA 612
>XP_006719496
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           LNT G TT+
Sbjct: 165 LNTSGKTTS 173
>XP_006719495
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           LNT G TT+
Sbjct: 241 LNTSGKTTS 249
>XP_006719494
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           LNT G TT+
Sbjct: 293 LNTSGKTTS 301
>XP_006719493
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           LNT G TT+
Sbjct: 293 LNTSGKTTS 301
>XP_006719492
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVGTTTA 9
           LNT G TT+
Sbjct: 293 LNTSGKTTS 301
>XP_005272148
          Length = 692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 22 INTAGTSNA 30
>XP_005272147
          Length = 732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 22 INTAGTSNA 30
>XP_006714755
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 37 INTAGTSNA 45
>XP_005272145
          Length = 747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 37 INTAGTSNA 45
>XP_005272144
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 37 INTAGTSNA 45
>XP_005272143
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 37 INTAGTSNA 45
>XP_005272142
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 37 INTAGTSNA 45
>XP_005272141
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 37 INTAGTSNA 45
>XP_005272140
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 37 INTAGTSNA 45
>XP_005272139
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LNTVGTTTA 9
          +NT GT+ A
Sbjct: 37 INTAGTSNA 45
>NP_001273
          Length = 937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGTTTA 9
           VGTTTA
Sbjct: 607 VGTTTA 612
>NP_001025177
          Length = 951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGTTTA 9
           VGTTTA
Sbjct: 607 VGTTTA 612
>NP_000892
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LNTVGTTTA 9
           +N+V +TTA
Sbjct: 210 INSVSSTTA 218
>NP_001159576
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LNTVGTTTA 9
           +N+V +TTA
Sbjct: 210 INSVSSTTA 218
>NP_112092
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTVGTTT 8
           N+VGTT+
Sbjct: 121 NSVGTTS 127
>NP_849157
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTVGTTTA 9
           NT+ TTT+
Sbjct: 753 NTIRTTTS 760
>NP_663612
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTVGTTT 8
           N+VGTT+
Sbjct: 121 NSVGTTS 127
>XP_006724281
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTVGTTT 8
           N+VGTT+
Sbjct: 121 NSVGTTS 127
>XP_006724280
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTVGTTT 8
           N+VGTT+
Sbjct: 199 NSVGTTS 205
>XP_006714285
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LNTVGTTTA 9
           +N+V +TTA
Sbjct: 210 INSVSSTTA 218
>XP_005263071
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LNTVGTTTA 9
           +N+V +TTA
Sbjct: 210 INSVSSTTA 218
>XP_006714159
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTVGTTTA 9
           NT+ TTT+
Sbjct: 753 NTIRTTTS 760
>XP_006714158
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTVGTTTA 9
           NT+ TTT+
Sbjct: 753 NTIRTTTS 760
>XP_006714157
          Length = 1077

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTVGTTTA 9
           NT+ TTT+
Sbjct: 753 NTIRTTTS 760
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.113    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,742
Number of extensions: 528
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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