Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_958441                                                              20     390
NP_958439                                                              20     390
NP_958440                                                              20     390
NP_005219                                                              20     390
NP_061963                                                              18    1935
NP_689479                                                              17    4312
NP_776175                                                              17    4312
NP_001122089                                                           17    4312
NP_114128                                                              17    4312
NP_001273541                                                           17    4312
NP_001273540                                                           17    4312
XP_005259451                                                           17    4312
XP_005259450                                                           17    4312
XP_005254368                                                           17    4312
XP_005254367                                                           17    4312
XP_006720536                                                           17    4312
XP_005267236                                                           17    4312
XP_005267235                                                           17    4312
XP_006715650                                                           17    4312
XP_005267234                                                           17    4312
NP_060795                                                              16    5631
NP_001242983                                                           16    5631
XP_006716802                                                           16    5631
NP_055968                                                              16    7355
NP_859063                                                              16    7355
NP_001277188                                                           16    7355
NP_663320                                                              16    7355
NP_001070730                                                           16    7355
NP_892120                                                              16    7355
XP_006715490                                                           16    7355
XP_005248760                                                           16    7355
XP_005248759                                                           16    7355
XP_006715489                                                           16    7355
XP_005248758                                                           16    7355
NP_001138427                                                           15    9605
NP_064619                                                              15    9605
NP_056366                                                              15    9605
NP_001982                                                              15    9605
NP_114141                                                              15    9605
NP_115796                                                              15    9605
XP_005257201                                                           15    9605
XP_005254619                                                           15    9605
XP_005254618                                                           15    9605
XP_005268513                                                           15    9605
XP_005268512                                                           15    9605
XP_005268510                                                           15    9605
XP_005268509                                                           15    9605
XP_005265092                                                           15    9605
XP_005265091                                                           15    9605
NP_005297                                                              15    9605
>NP_958441
          Length = 705

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LNTVEQIPL 9
           LNTVE+IPL
Sbjct: 93  LNTVERIPL 101
>NP_958439
          Length = 628

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LNTVEQIPL 9
           LNTVE+IPL
Sbjct: 93  LNTVERIPL 101
>NP_958440
          Length = 405

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LNTVEQIPL 9
           LNTVE+IPL
Sbjct: 93  LNTVERIPL 101
>NP_005219
          Length = 1210

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LNTVEQIPL 9
           LNTVE+IPL
Sbjct: 93  LNTVERIPL 101
>NP_061963
          Length = 1047

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LNTVEQIPL 9
           +NT+ Q+PL
Sbjct: 531 INTIRQLPL 539
>NP_689479
          Length = 215

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LNTVEQIP 8
           L TV+QIP
Sbjct: 160 LRTVQQIP 167
>NP_776175
          Length = 1150

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTVEQIPL 9
           NT+E +PL
Sbjct: 511 NTLEDVPL 518
>NP_001122089
          Length = 769

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LNTVEQIPL 9
          +NTV+ +PL
Sbjct: 90 INTVKDLPL 98
>NP_114128
          Length = 795

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LNTVEQIPL 9
          +NTV+ +PL
Sbjct: 90 INTVKDLPL 98
>NP_001273541
          Length = 705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LNTVEQIPL 9
          +NTV+ +PL
Sbjct: 90 INTVKDLPL 98
>NP_001273540
          Length = 796

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LNTVEQIPL 9
          +NTV+ +PL
Sbjct: 90 INTVKDLPL 98
>XP_005259451
          Length = 120

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LNTVEQIP 8
          L TV+QIP
Sbjct: 65 LRTVQQIP 72
>XP_005259450
          Length = 172

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LNTVEQIP 8
           L TV+QIP
Sbjct: 117 LRTVQQIP 124
>XP_005254368
          Length = 712

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTVEQIPL 9
           NT+E +PL
Sbjct: 511 NTLEDVPL 518
>XP_005254367
          Length = 1031

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTVEQIPL 9
           NT+E +PL
Sbjct: 392 NTLEDVPL 399
>XP_006720536
          Length = 1072

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTVEQIPL 9
           NT+E +PL
Sbjct: 433 NTLEDVPL 440
>XP_005267236
          Length = 768

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LNTVEQIPL 9
          +NTV+ +PL
Sbjct: 90 INTVKDLPL 98
>XP_005267235
          Length = 773

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LNTVEQIPL 9
          +NTV+ +PL
Sbjct: 90 INTVKDLPL 98
>XP_006715650
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LNTVEQIPL 9
          +NTV+ +PL
Sbjct: 90 INTVKDLPL 98
>XP_005267234
          Length = 795

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LNTVEQIPL 9
          +NTV+ +PL
Sbjct: 90 INTVKDLPL 98
>NP_060795
          Length = 481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LNTVEQIP 8
           +NTV+Q+P
Sbjct: 312 VNTVKQMP 319
>NP_001242983
          Length = 481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LNTVEQIP 8
           +NTV+Q+P
Sbjct: 312 VNTVKQMP 319
>XP_006716802
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LNTVEQIP 8
           +NTV+Q+P
Sbjct: 312 VNTVKQMP 319
>NP_055968
          Length = 2039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NTVEQIP 8
            NTV++IP
Sbjct: 1491 NTVKEIP 1497
>NP_859063
          Length = 995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NTVEQIPL 9
          NT+++IP+
Sbjct: 50 NTIKRIPI 57
>NP_001277188
          Length = 1951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NTVEQIP 8
            NTV++IP
Sbjct: 1403 NTVKEIP 1409
>NP_663320
          Length = 487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVEQIPL 9
           L T+E IPL
Sbjct: 194 LRTLEPIPL 202
>NP_001070730
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVEQIPL 9
           L T+E IPL
Sbjct: 107 LRTLEPIPL 115
>NP_892120
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNTVEQIPL 9
           L T+E IPL
Sbjct: 227 LRTLEPIPL 235
>XP_006715490
          Length = 1181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTVEQIP 8
           NTV++IP
Sbjct: 633 NTVKEIP 639
>XP_005248760
          Length = 1308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTVEQIP 8
           NTV++IP
Sbjct: 760 NTVKEIP 766
>XP_005248759
          Length = 1951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NTVEQIP 8
            NTV++IP
Sbjct: 1403 NTVKEIP 1409
>XP_006715489
          Length = 2039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NTVEQIP 8
            NTV++IP
Sbjct: 1491 NTVKEIP 1497
>XP_005248758
          Length = 2039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NTVEQIP 8
            NTV++IP
Sbjct: 1491 NTVKEIP 1497
>NP_001138427
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VEQIPL 9
          +EQIPL
Sbjct: 81 IEQIPL 86
>NP_064619
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VEQIPL 9
          +EQIPL
Sbjct: 81 IEQIPL 86
>NP_056366
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LNTVEQIP 8
           +NTV+Q P
Sbjct: 500 VNTVKQTP 507
>NP_001982
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LNTVEQIPL 9
           LNTV  +P+
Sbjct: 102 LNTVALVPI 110
>NP_114141
          Length = 5635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LNTVEQIPL 9
           L+T+E IP+
Sbjct: 990 LSTIEGIPV 998
>NP_115796
          Length = 1237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVEQIPL 9
            T+E+IPL
Sbjct: 1207 TLEEIPL 1213
>XP_005257201
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LNTVEQIPL 9
           LNTV  +P+
Sbjct: 108 LNTVALVPI 116
>XP_005254619
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VEQIPL 9
          +EQIPL
Sbjct: 81 IEQIPL 86
>XP_005254618
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  VEQIPL 9
          +EQIPL
Sbjct: 81 IEQIPL 86
>XP_005268513
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TVEQIPL 9
           T+E+IPL
Sbjct: 828 TLEEIPL 834
>XP_005268512
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TVEQIPL 9
           T+E+IPL
Sbjct: 828 TLEEIPL 834
>XP_005268510
          Length = 1215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVEQIPL 9
            T+E+IPL
Sbjct: 1185 TLEEIPL 1191
>XP_005268509
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVEQIPL 9
            T+E+IPL
Sbjct: 1251 TLEEIPL 1257
>XP_005265092
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LNTVEQIP 8
           +NTV+Q P
Sbjct: 322 VNTVKQTP 329
>XP_005265091
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LNTVEQIP 8
           +NTV+Q P
Sbjct: 437 VNTVKQTP 444
>NP_005297
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LNTVEQI 7
           LNT EQ+
Sbjct: 150 LNTTEQV 156
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.137    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 530,205
Number of extensions: 810
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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