Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1482
NP_001075109                                                           18    1482
NP_002630                                                              17    4312
NP_001269504                                                           17    4312
NP_001269507                                                           17    4312
NP_001269506                                                           17    4312
NP_954595                                                              17    4312
NP_954673                                                              17    4312
NP_071887                                                              17    4312
NP_001027459                                                           17    4312
NP_068823                                                              17    4312
NP_001244328                                                           17    4312
NP_001244327                                                           17    4312
NP_001244324                                                           17    4312
NP_001244322                                                           17    4312
NP_001269508                                                           17    4312
NP_001269505                                                           17    4312
NP_001244326                                                           17    4312
NP_001244323                                                           17    4312
NP_001257457                                                           16    5631
NP_060080                                                              16    5631
NP_001257458                                                           16    5631
NP_001257459                                                           16    5631
NP_002709                                                              16    5631
NP_003341                                                              16    5631
XP_006720643                                                           16    5631
XP_006720642                                                           16    5631
XP_005254536                                                           16    5631
XP_006720641                                                           16    5631
XP_006720640                                                           16    5631
XP_005254533                                                           16    5631
XP_005254532                                                           16    5631
XP_006720639                                                           16    5631
XP_005254530                                                           16    5631
XP_006720638                                                           16    5631
XP_005251357                                                           16    5631
XP_006713749                                                           16    5631
NP_001001872                                                           16    5631
NP_071410                                                              16    7355
NP_001186562                                                           16    7355
NP_001017403                                                           16    7355
NP_996920                                                              16    7355
NP_067649                                                              16    7355
NP_001017404                                                           16    7355
NP_996919                                                              16    7355
NP_001026                                                              16    7355
XP_005254670                                                           16    7355
XP_006720721                                                           16    7355
XP_006711873                                                           16    7355
XP_006711872                                                           16    7355
XP_006711871                                                           16    7355
XP_006711870                                                           16    7355
XP_006711869                                                           16    7355
XP_006711868                                                           16    7355
XP_006711867                                                           16    7355
XP_006711866                                                           16    7355
XP_006711865                                                           16    7355
XP_006711543                                                           16    7355
XP_005245461                                                           16    7355
NP_002560                                                              15    9605
NP_001276753                                                           15    9605
NP_001159751                                                           15    9605
NP_055686                                                              15    9605
NP_001120932                                                           15    9605
NP_002284                                                              15    9605
NP_001276752                                                           15    9605
NP_001091742                                                           15    9605
NP_001138502                                                           15    9605
NP_054722                                                              15    9605
NP_079007                                                              15    9605
NP_002121                                                              15    9605
XP_005256326                                                           15    9605
XP_005256206                                                           15    9605
XP_005248352                                                           15    9605
NP_115536                                                              15    9605
>NP_008835
          Length = 4128

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LNSLYSLKI 9
            LNSLYS KI
Sbjct: 2542 LNSLYSPKI 2550
>NP_001075109
          Length = 4097

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LNSLYSLKI 9
            LNSLYS KI
Sbjct: 2542 LNSLYSPKI 2550
>NP_002630
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LNSLYSLKI 9
          L+S YSLK+
Sbjct: 80 LSSFYSLKL 88
>NP_001269504
          Length = 91

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 6  NRIYSLKI 13
>NP_001269507
          Length = 91

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 6  NRIYSLKI 13
>NP_001269506
          Length = 91

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 6  NRIYSLKI 13
>NP_954595
          Length = 170

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 85 NRIYSLKI 92
>NP_954673
          Length = 370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSLYSLKI 9
           N +YSLKI
Sbjct: 285 NRIYSLKI 292
>NP_071887
          Length = 103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 18 NRIYSLKI 25
>NP_001027459
          Length = 147

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 62 NRIYSLKI 69
>NP_068823
          Length = 170

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 85 NRIYSLKI 92
>NP_001244328
          Length = 105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 20 NRIYSLKI 27
>NP_001244327
          Length = 105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 20 NRIYSLKI 27
>NP_001244324
          Length = 144

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 59 NRIYSLKI 66
>NP_001244322
          Length = 170

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 85 NRIYSLKI 92
>NP_001269508
          Length = 105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 20 NRIYSLKI 27
>NP_001269505
          Length = 105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 20 NRIYSLKI 27
>NP_001244326
          Length = 105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 20 NRIYSLKI 27
>NP_001244323
          Length = 103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLKI
Sbjct: 18 NRIYSLKI 25
>NP_001257457
          Length = 995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 9  NELYTLKV 16
>NP_060080
          Length = 986

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 9  NELYTLKV 16
>NP_001257458
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 9  NELYTLKV 16
>NP_001257459
          Length = 994

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 9  NELYTLKV 16
>NP_002709
          Length = 1150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSLYSLKI 9
           NSLY+L++
Sbjct: 375 NSLYNLEV 382
>NP_003341
          Length = 145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLK+
Sbjct: 60 NRIYSLKV 67
>XP_006720643
          Length = 1003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 9  NELYTLKV 16
>XP_006720642
          Length = 1003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 9  NELYTLKV 16
>XP_005254536
          Length = 1003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 9  NELYTLKV 16
>XP_006720641
          Length = 1008

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 32 NELYTLKV 39
>XP_006720640
          Length = 1009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 32 NELYTLKV 39
>XP_005254533
          Length = 1016

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 32 NELYTLKV 39
>XP_005254532
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 32 NELYTLKV 39
>XP_006720639
          Length = 1018

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 32 NELYTLKV 39
>XP_005254530
          Length = 1025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 32 NELYTLKV 39
>XP_006720638
          Length = 1026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N LY+LK+
Sbjct: 32 NELYTLKV 39
>XP_005251357
          Length = 105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          N +YSLK+
Sbjct: 20 NRIYSLKV 27
>XP_006713749
          Length = 1150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NSLYSLKI 9
           NSLY+L++
Sbjct: 375 NSLYNLEV 382
>NP_001001872
          Length = 774

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LNSLYSLKI 9
           L +LYS+K+
Sbjct: 729 LGALYSIKV 737
>NP_071410
          Length = 691

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSLYSLK 8
           +SLYSLK
Sbjct: 665 HSLYSLK 671
>NP_001186562
          Length = 691

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSLYSLK 8
           +SLYSLK
Sbjct: 665 HSLYSLK 671
>NP_001017403
          Length = 967

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSLYSLKI 9
           + LYSLKI
Sbjct: 111 SGLYSLKI 118
>NP_996920
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSLYSLK 8
           NSL+SLK
Sbjct: 391 NSLHSLK 397
>NP_067649
          Length = 915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          + LYSLKI
Sbjct: 59 SGLYSLKI 66
>NP_001017404
          Length = 828

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          + LYSLKI
Sbjct: 68 SGLYSLKI 75
>NP_996919
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSLYSLK 8
           NSL+SLK
Sbjct: 391 NSLHSLK 397
>NP_001026
          Length = 4967

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_005254670
          Length = 648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSLYSLK 8
           NSL+SLK
Sbjct: 333 NSLHSLK 339
>XP_006720721
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   NSLYSLK 8
           NSL+SLK
Sbjct: 391 NSLHSLK 397
>XP_006711873
          Length = 4954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711872
          Length = 2735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711871
          Length = 4906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711870
          Length = 4965

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711869
          Length = 4973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711868
          Length = 4975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711867
          Length = 4977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711866
          Length = 4984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711865
          Length = 4985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LNSLYSL 7
           LNSLY L
Sbjct: 530 LNSLYEL 536
>XP_006711543
          Length = 895

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSLYSLKI 9
           + LYSLKI
Sbjct: 111 SGLYSLKI 118
>XP_005245461
          Length = 924

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NSLYSLKI 9
          + LYSLKI
Sbjct: 68 SGLYSLKI 75
>NP_002560
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSLYSLKI 9
           NS+Y+L I
Sbjct: 310 NSIYTLSI 317
>NP_001276753
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSLYSLKI 9
           NS+Y+L I
Sbjct: 310 NSIYTLSI 317
>NP_001159751
          Length = 1201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNSLYSLKI 9
           LNS Y+L I
Sbjct: 925 LNSRYNLNI 933
>NP_055686
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNSLYSLKI 9
           LNS Y+L I
Sbjct: 922 LNSRYNLNI 930
>NP_001120932
          Length = 1202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNSLYSLKI 9
           LNS Y+L I
Sbjct: 926 LNSRYNLNI 934
>NP_002284
          Length = 1609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LNSLYSLKI 9
           LN+L S+KI
Sbjct: 648 LNNLTSIKI 656
>NP_001276752
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSLYSLKI 9
           NS+Y+L I
Sbjct: 310 NSIYTLSI 317
>NP_001091742
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLYSLKI 9
           +LYSLK+
Sbjct: 382 TLYSLKV 388
>NP_001138502
          Length = 1692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    LNSLYSLKI 9
            L  LY LKI
Sbjct: 1385 LEKLYELKI 1393
>NP_054722
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNSLYSLKI 9
           LNS+Y L I
Sbjct: 921 LNSMYQLWI 929
>NP_079007
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LNSLYSLK 8
           L S+YSLK
Sbjct: 154 LASIYSLK 161
>NP_002121
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLYSLKI 9
           +LYSLK+
Sbjct: 382 TLYSLKV 388
>XP_005256326
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNSLYSLKI 9
           LNS+Y L I
Sbjct: 886 LNSMYQLWI 894
>XP_005256206
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LNSLYSLK 8
           L S+YSLK
Sbjct: 154 LASIYSLK 161
>XP_005248352
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLYSLKI 9
           +LYSLK+
Sbjct: 340 TLYSLKV 346
>NP_115536
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    SLYSLK 8
            SLYSLK
Sbjct: 1057 SLYSLK 1062
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.137    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 459,859
Number of extensions: 789
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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