Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     390
XP_005262424                                                           20     390
XP_005251866                                                           19     665
XP_005251865                                                           19     665
XP_005251864                                                           19     665
NP_055745                                                              19     665
NP_115518                                                              17    2528
XP_006722394                                                           17    2528
XP_005258167                                                           17    2528
XP_006722393                                                           17    2528
XP_006722392                                                           17    2528
XP_006722391                                                           17    2528
XP_006722390                                                           17    2528
XP_005258166                                                           17    2528
XP_006722389                                                           17    2528
XP_005258165                                                           17    2528
XP_005258164                                                           17    2528
NP_065853                                                              17    3301
XP_005271684                                                           17    3301
NP_006232                                                              17    4312
NP_001182741                                                           17    4312
NP_689879                                                              17    4312
NP_001182740                                                           17    4312
XP_006713746                                                           17    4312
XP_006713745                                                           17    4312
XP_006711815                                                           17    4312
NP_002684                                                              16    5631
NP_001119603                                                           16    5631
NP_775866                                                              16    5631
NP_072174                                                              16    5631
XP_006712785                                                           16    5631
XP_005246883                                                           16    5631
XP_005246882                                                           16    5631
XP_006712784                                                           16    5631
NP_000531                                                              16    7355
NP_001036188                                                           16    7355
NP_061330                                                              16    7355
NP_060069                                                              16    7355
NP_001273654                                                           16    7355
NP_065917                                                              16    7355
NP_055646                                                              16    7355
XP_006723382                                                           16    7355
XP_006723381                                                           16    7355
XP_006723380                                                           16    7355
XP_006719549                                                           16    7355
XP_006719548                                                           16    7355
XP_006719547                                                           16    7355
XP_006719546                                                           16    7355
XP_006719545                                                           16    7355
XP_006719544                                                           16    7355
XP_006719543                                                           16    7355
XP_006719542                                                           16    7355
XP_006719541                                                           16    7355
XP_006719540                                                           16    7355
XP_006713495                                                           16    7355
NP_001012302                                                           15    9605
NP_671692                                                              15    9605
XP_006718283                                                           15    9605
XP_006718282                                                           15    9605
NP_064617                                                              15    9605
>NP_722576
          Length = 3080

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LNNKTATTE 9
           L+NKTATTE
Sbjct: 897 LDNKTATTE 905
>XP_005262424
          Length = 2875

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LNNKTATTE 9
           L+NKTATTE
Sbjct: 692 LDNKTATTE 700
>XP_005251866
          Length = 621

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LNNKTATTE 9
          +NNKT TTE
Sbjct: 81 INNKTLTTE 89
>XP_005251865
          Length = 682

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LNNKTATTE 9
           +NNKT TTE
Sbjct: 142 INNKTLTTE 150
>XP_005251864
          Length = 683

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LNNKTATTE 9
           +NNKT TTE
Sbjct: 143 INNKTLTTE 151
>NP_055745
          Length = 683

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LNNKTATTE 9
           +NNKT TTE
Sbjct: 143 INNKTLTTE 151
>NP_115518
          Length = 2537

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1972 INNKTAT 1978
>XP_006722394
          Length = 1845

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1279 INNKTAT 1285
>XP_005258167
          Length = 1856

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1290 INNKTAT 1296
>XP_006722393
          Length = 2199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1633 INNKTAT 1639
>XP_006722392
          Length = 2444

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1878 INNKTAT 1884
>XP_006722391
          Length = 2448

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1882 INNKTAT 1888
>XP_006722390
          Length = 2467

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1902 INNKTAT 1908
>XP_005258166
          Length = 2468

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1902 INNKTAT 1908
>XP_006722389
          Length = 2506

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1972 INNKTAT 1978
>XP_005258165
          Length = 2534

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1968 INNKTAT 1974
>XP_005258164
          Length = 2538

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LNNKTAT 7
            +NNKTAT
Sbjct: 1972 INNKTAT 1978
>NP_065853
          Length = 1117

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNNKTATTE 9
           L NKT TT+
Sbjct: 649 LKNKTGTTQ 657
>XP_005271684
          Length = 1081

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LNNKTATTE 9
           L NKT TT+
Sbjct: 649 LKNKTGTTQ 657
>NP_006232
          Length = 205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LNNKTATT 8
          L NKT+TT
Sbjct: 15 LKNKTSTT 22
>NP_001182741
          Length = 328

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LNNKTATTE 9
           L+NKTAT +
Sbjct: 311 LSNKTATDD 319
>NP_689879
          Length = 536

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LNNKTATTE 9
           L+NKTAT +
Sbjct: 519 LSNKTATDD 527
>NP_001182740
          Length = 474

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LNNKTATTE 9
           L+NKTAT +
Sbjct: 457 LSNKTATDD 465
>XP_006713746
          Length = 108

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LNNKTATT 8
          L NKT+TT
Sbjct: 15 LKNKTSTT 22
>XP_006713745
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LNNKTATT 8
          L NKT+TT
Sbjct: 15 LKNKTSTT 22
>XP_006711815
          Length = 536

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LNNKTATTE 9
           L+NKTAT +
Sbjct: 519 LSNKTATDD 527
>NP_002684
          Length = 1239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LNNKTATT 8
           L++KTATT
Sbjct: 931 LHSKTATT 938
>NP_001119603
          Length = 1239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LNNKTATT 8
           L++KTATT
Sbjct: 931 LHSKTATT 938
>NP_775866
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LNNKTATTE 9
           +NN+ +TTE
Sbjct: 832 INNQDSTTE 840
>NP_072174
          Length = 1735

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LNNKTATT 8
            L+NK ATT
Sbjct: 1259 LHNKVATT 1266
>XP_006712785
          Length = 1352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LNNKTATT 8
           L+NK ATT
Sbjct: 876 LHNKVATT 883
>XP_005246883
          Length = 1352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LNNKTATT 8
           L+NK ATT
Sbjct: 876 LHNKVATT 883
>XP_005246882
          Length = 1518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LNNKTATT 8
            L+NK ATT
Sbjct: 1042 LHNKVATT 1049
>XP_006712784
          Length = 1784

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LNNKTATT 8
            L+NK ATT
Sbjct: 1308 LHNKVATT 1315
>NP_000531
          Length = 5038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    NNKTATTE 9
            N K ATTE
Sbjct: 1374 NEKDATTE 1381
>NP_001036188
          Length = 5033

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    NNKTATTE 9
            N K ATTE
Sbjct: 1374 NEKDATTE 1381
>NP_061330
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LNNKTATTE 9
           +NN T T+E
Sbjct: 314 VNNSTGTSE 322
>NP_060069
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 648 SNKSATTD 655
>NP_001273654
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NNKTATT 8
           NNK ATT
Sbjct: 408 NNKGATT 414
>NP_065917
          Length = 748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NNKTATT 8
           NNK ATT
Sbjct: 469 NNKGATT 475
>NP_055646
          Length = 2925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNNKTATTE 9
            LN+ TAT E
Sbjct: 997  LNDTTATVE 1005
>XP_006723382
          Length = 5027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    NNKTATTE 9
            N K ATTE
Sbjct: 1374 NEKDATTE 1381
>XP_006723381
          Length = 5031

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    NNKTATTE 9
            N K ATTE
Sbjct: 1373 NEKDATTE 1380
>XP_006723380
          Length = 5032

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    NNKTATTE 9
            N K ATTE
Sbjct: 1374 NEKDATTE 1381
>XP_006719549
          Length = 631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 500 SNKSATTD 507
>XP_006719548
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 504 SNKSATTD 511
>XP_006719547
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 504 SNKSATTD 511
>XP_006719546
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 504 SNKSATTD 511
>XP_006719545
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 574 SNKSATTD 581
>XP_006719544
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 574 SNKSATTD 581
>XP_006719543
          Length = 735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 604 SNKSATTD 611
>XP_006719542
          Length = 735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 604 SNKSATTD 611
>XP_006719541
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 622 SNKSATTD 629
>XP_006719540
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NNKTATTE 9
           +NK+ATT+
Sbjct: 652 SNKSATTD 659
>XP_006713495
          Length = 2969

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LNNKTATTE 9
            LN+ TAT E
Sbjct: 1041 LNDTTATVE 1049
>NP_001012302
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LNNKTATTE 9
           +NNKT+  E
Sbjct: 128 MNNKTSAGE 136
>NP_671692
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  NNKTATTE 9
          NN  ATTE
Sbjct: 27 NNPYATTE 34
>XP_006718283
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LNNKTATTE 9
           +NNKT+  E
Sbjct: 128 MNNKTSAGE 136
>XP_006718282
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LNNKTATTE 9
           +NNKT+  E
Sbjct: 128 MNNKTSAGE 136
>NP_064617
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  NNKTATTE 9
          NN  ATTE
Sbjct: 58 NNPYATTE 65
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286    0.101    0.241 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 440,889
Number of extensions: 652
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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