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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           20     390
NP_000170                                                              20     390
NP_001268422                                                           20     390
NP_001268423                                                           20     390
XP_005264328                                                           20     390
NP_001229277                                                           17    3301
NP_085135                                                              17    4312
XP_005258413                                                           17    4312
NP_006552                                                              16    5631
NP_612357                                                              16    5631
NP_001274420                                                           16    5631
XP_006717432                                                           16    5631
XP_006712026                                                           16    5631
XP_005264244                                                           16    5631
NP_065944                                                              15    9605
NP_443179                                                              15    9605
XP_005266703                                                           15    9605

>NP_001268421
          Length = 1230

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LMLVPDKIS 9
           LM+VPDKIS
Sbjct: 668 LMVVPDKIS 676



>NP_000170
          Length = 1360

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LMLVPDKIS 9
           LM+VPDKIS
Sbjct: 798 LMVVPDKIS 806



>NP_001268422
          Length = 1058

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LMLVPDKIS 9
           LM+VPDKIS
Sbjct: 496 LMVVPDKIS 504



>NP_001268423
          Length = 1058

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LMLVPDKIS 9
           LM+VPDKIS
Sbjct: 496 LMVVPDKIS 504



>XP_005264328
          Length = 1261

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LMLVPDKIS 9
           LM+VPDKIS
Sbjct: 699 LMVVPDKIS 707



>NP_001229277
          Length = 104

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LVPDKIS 9
          LVPDK+S
Sbjct: 44 LVPDKLS 50



>NP_085135
          Length = 2248

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LMLVPDKIS 9
            L LVPDK++
Sbjct: 1562 LPLVPDKLN 1570



>XP_005258413
          Length = 2249

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LMLVPDKIS 9
            L LVPDK++
Sbjct: 1563 LPLVPDKLN 1571



>NP_006552
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  MLVPDKIS 9
          +LVPD+I+
Sbjct: 19 LLVPDRIN 26



>NP_612357
          Length = 352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LMLVPDKI 8
           LML+P+K+
Sbjct: 154 LMLLPEKL 161



>NP_001274420
          Length = 1795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LVPDKIS 9
            +VPDK+S
Sbjct: 1467 IVPDKLS 1473



>XP_006717432
          Length = 525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  MLVPDKIS 9
          +LVPD+I+
Sbjct: 19 LLVPDRIN 26



>XP_006712026
          Length = 937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVPDKIS 9
           +VPDK+S
Sbjct: 609 IVPDKLS 615



>XP_005264244
          Length = 1795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LVPDKIS 9
            +VPDK+S
Sbjct: 1467 IVPDKLS 1473



>NP_065944
          Length = 1701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVPDKIS 9
           +VP+KIS
Sbjct: 160 IVPEKIS 166



>NP_443179
          Length = 2170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 2    MLVPDKI 8
            +++PDK+
Sbjct: 1266 LIIPDKV 1272



>XP_005266703
          Length = 1501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 2   MLVPDKI 8
           +++PDK+
Sbjct: 597 LIIPDKV 603



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.144    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 609,072
Number of extensions: 410
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)