Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           20     509
NP_000242                                                              20     509
XP_005264389                                                           20     509
NP_001268421                                                           17    2528
NP_000170                                                              17    2528
NP_001268422                                                           17    2528
NP_001268423                                                           17    2528
XP_005264328                                                           17    2528
NP_001269287                                                           17    4312
NP_078894                                                              17    4312
NP_001269072                                                           17    4312
NP_001269073                                                           17    4312
NP_694995                                                              17    4312
NP_001186224                                                           17    4312
XP_006723191                                                           17    4312
XP_005271729                                                           17    4312
XP_005271727                                                           17    4312
XP_005271728                                                           17    4312
XP_006718967                                                           17    4312
XP_005271726                                                           17    4312
NP_001137540                                                           16    5631
NP_003881                                                              16    5631
NP_077007                                                              16    7355
NP_109589                                                              16    7355
NP_001001484                                                           16    7355
NP_001248767                                                           16    7355
NP_001248766                                                           16    7355
NP_001103132                                                           16    7355
NP_036307                                                              16    7355
NP_208385                                                              16    7355
NP_001248765                                                           16    7355
XP_005252908                                                           16    7355
XP_006717601                                                           16    7355
XP_006717600                                                           16    7355
XP_006714990                                                           16    7355
NP_031399                                                              15    9605
NP_001017975                                                           15    9605
NP_001255968                                                           15    9605
NP_065076                                                              15    9605
NP_055973                                                              15    9605
NP_001243805                                                           15    9605
NP_694856                                                              15    9605
NP_001243806                                                           15    9605
NP_005863                                                              15    9605
NP_001718                                                              15    9605
XP_005262522                                                           15    9605
XP_005262521                                                           15    9605
XP_006723662                                                           15    9605
XP_005260825                                                           15    9605
XP_006723661                                                           15    9605
XP_006716810                                                           15    9605
XP_005251476                                                           15    9605
XP_005251475                                                           15    9605
XP_005251473                                                           15    9605
XP_005251474                                                           15    9605
XP_005251472                                                           15    9605
XP_005251471                                                           15    9605
XP_005251470                                                           15    9605
XP_006716809                                                           15    9605
XP_006716808                                                           15    9605
XP_006716807                                                           15    9605
XP_006716806                                                           15    9605
XP_005251468                                                           15    9605
XP_005251467                                                           15    9605
XP_005273450                                                           15    9605
XP_005273448                                                           15    9605
XP_006710458                                                           15    9605
NP_444277                                                              15    9605
NP_689850                                                              15    9605
>NP_001245210
          Length = 868

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           LMAQIGC V
Sbjct: 621 LMAQIGCFV 629
>NP_000242
          Length = 934

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           LMAQIGC V
Sbjct: 687 LMAQIGCFV 695
>XP_005264389
          Length = 921

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           LMAQIGC V
Sbjct: 687 LMAQIGCFV 695
>NP_001268421
          Length = 1230

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LMAQIGCSV 9
            +MAQ+GC V
Sbjct: 1022 VMAQMGCYV 1030
>NP_000170
          Length = 1360

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LMAQIGCSV 9
            +MAQ+GC V
Sbjct: 1152 VMAQMGCYV 1160
>NP_001268422
          Length = 1058

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           +MAQ+GC V
Sbjct: 850 VMAQMGCYV 858
>NP_001268423
          Length = 1058

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           +MAQ+GC V
Sbjct: 850 VMAQMGCYV 858
>XP_005264328
          Length = 1261

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LMAQIGCSV 9
            +MAQ+GC V
Sbjct: 1053 VMAQMGCYV 1061
>NP_001269287
          Length = 975

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 638 VLAQLGCPI 646
>NP_078894
          Length = 975

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 638 VLAQLGCPI 646
>NP_001269072
          Length = 975

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 638 VLAQLGCPI 646
>NP_001269073
          Length = 975

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 638 VLAQLGCPI 646
>NP_694995
          Length = 627

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LMAQIGC 7
          LMA +GC
Sbjct: 49 LMASVGC 55
>NP_001186224
          Length = 640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LMAQIGC 7
          LMA +GC
Sbjct: 62 LMASVGC 68
>XP_006723191
          Length = 618

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LMAQIGC 7
          LMA +GC
Sbjct: 40 LMASVGC 46
>XP_005271729
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 460 VLAQLGCPI 468
>XP_005271727
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 460 VLAQLGCPI 468
>XP_005271728
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 460 VLAQLGCPI 468
>XP_006718967
          Length = 921

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 638 VLAQLGCPI 646
>XP_005271726
          Length = 975

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LMAQIGCSV 9
           ++AQ+GC +
Sbjct: 638 VLAQLGCPI 646
>NP_001137540
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LMAQIGC 7
          LMA +GC
Sbjct: 62 LMASLGC 68
>NP_003881
          Length = 5405

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3    AQIGCSV 9
            AQ+GC +
Sbjct: 1942 AQVGCEI 1948

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3    AQIGCSV 9
            AQ+GC +
Sbjct: 3143 AQVGCEI 3149

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3    AQIGCSV 9
            AQ+GC +
Sbjct: 4344 AQVGCEI 4350
>NP_077007
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   AQIGCS 8
           +QIGCS
Sbjct: 204 SQIGCS 209
>NP_109589
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQ+GC V
Sbjct: 192 AQLGCPV 198
>NP_001001484
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQ+GC V
Sbjct: 192 AQLGCPV 198
>NP_001248767
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  AQIGCSV 9
          AQ+GC V
Sbjct: 43 AQLGCPV 49
>NP_001248766
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQ+GC V
Sbjct: 192 AQLGCPV 198
>NP_001103132
          Length = 4284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   LMAQIGCS 8
           + A++GCS
Sbjct: 876 VFAEVGCS 883
>NP_036307
          Length = 471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQIGC +
Sbjct: 132 AQIGCKL 138
>NP_208385
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQIGC +
Sbjct: 132 AQIGCKL 138
>NP_001248765
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQ+GC V
Sbjct: 192 AQLGCPV 198
>XP_005252908
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQIGC +
Sbjct: 127 AQIGCKL 133
>XP_006717601
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQ+GC V
Sbjct: 192 AQLGCPV 198
>XP_006717600
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   AQIGCSV 9
           AQ+GC V
Sbjct: 213 AQLGCPV 219
>XP_006714990
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   MAQIGCSV 9
           M+Q GC +
Sbjct: 825 MSQFGCGI 832
>NP_031399
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LMAQIGCSV 9
           L A++GC V
Sbjct: 138 LPAEVGCLV 146
>NP_001017975
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   LMAQIGC 7
           + AQ+GC
Sbjct: 863 IQAQLGC 869
>NP_001255968
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LMAQIGCSV 9
           L A++GC V
Sbjct: 138 LPAEVGCLV 146
>NP_065076
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    LMAQIGCSV 9
            ++AQ+ C V
Sbjct: 1199 IVAQVACDV 1207
>NP_055973
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1286 LLAQPGCN 1293
>NP_001243805
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1286 LLAQPGCN 1293
>NP_694856
          Length = 1194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1128 LLAQPGCN 1135
>NP_001243806
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1286 LLAQPGCN 1293
>NP_005863
          Length = 225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LMAQIGCS 8
           LM+Q GC+
Sbjct: 126 LMSQHGCN 133
>NP_001718
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LMAQIGCSV 9
           L  +IGC V
Sbjct: 114 LFGRIGCKV 122
>XP_005262522
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LMAQIGCSV 9
           L  +IGC V
Sbjct: 114 LFGRIGCKV 122
>XP_005262521
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LMAQIGCSV 9
           L  +IGC V
Sbjct: 114 LFGRIGCKV 122
>XP_006723662
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    LMAQIGCSV 9
            ++AQ+ C V
Sbjct: 1246 IVAQVACDV 1254
>XP_005260825
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    LMAQIGCSV 9
            ++AQ+ C V
Sbjct: 1199 IVAQVACDV 1207
>XP_006723661
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    LMAQIGCSV 9
            ++AQ+ C V
Sbjct: 1246 IVAQVACDV 1254
>XP_006716810
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1128 LLAQPGCN 1135
>XP_005251476
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1128 LLAQPGCN 1135
>XP_005251475
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1128 LLAQPGCN 1135
>XP_005251473
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1128 LLAQPGCN 1135
>XP_005251474
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1128 LLAQPGCN 1135
>XP_005251472
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1128 LLAQPGCN 1135
>XP_005251471
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1128 LLAQPGCN 1135
>XP_005251470
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1206 LLAQPGCN 1213
>XP_006716809
          Length = 1334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1268 LLAQPGCN 1275
>XP_006716808
          Length = 1346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1268 LLAQPGCN 1275
>XP_006716807
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1286 LLAQPGCN 1293
>XP_006716806
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1286 LLAQPGCN 1293
>XP_005251468
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1286 LLAQPGCN 1293
>XP_005251467
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LMAQIGCS 8
            L+AQ GC+
Sbjct: 1286 LLAQPGCN 1293
>XP_005273450
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMAQIGCSV 9
           LMAQ+G  V
Sbjct: 112 LMAQLGAVV 120
>XP_005273448
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LMAQIGCSV 9
           LMAQ+G  V
Sbjct: 112 LMAQLGAVV 120
>XP_006710458
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   LMAQIGC 7
           + AQ+GC
Sbjct: 274 IQAQLGC 280
>NP_444277
          Length = 161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LMAQIG 6
           LMAQIG
Sbjct: 153 LMAQIG 158
>NP_689850
          Length = 244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LMAQIGC 7
          LMA +GC
Sbjct: 21 LMALLGC 27
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.137    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 510,341
Number of extensions: 581
Number of successful extensions: 71
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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