Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     509
NP_001013679                                                           18    1482
NP_667338                                                              17    2528
NP_001159608                                                           17    2528
XP_006713923                                                           17    2528
XP_006713922                                                           17    2528
NP_075561                                                              17    3301
NP_612154                                                              17    3301
NP_060876                                                              17    3301
NP_004523                                                              17    3301
XP_005248410                                                           17    3301
XP_006714553                                                           17    3301
XP_005248407                                                           17    3301
XP_005248406                                                           17    3301
XP_005248404                                                           17    3301
XP_005248403                                                           17    3301
XP_006714552                                                           17    3301
XP_005248402                                                           17    3301
NP_932349                                                              17    4312
NP_003025                                                              17    4312
XP_005253526                                                           17    4312
NP_004761                                                              16    5631
XP_006716546                                                           16    5631
XP_005265796                                                           16    5631
NP_001019782                                                           16    5631
NP_001186068                                                           16    7355
NP_067032                                                              16    7355
NP_001186067                                                           16    7355
NP_619639                                                              16    7355
NP_733842                                                              16    7355
NP_003004                                                              16    7355
NP_009041                                                              16    7355
NP_002935                                                              16    7355
NP_001181                                                              16    7355
NP_005863                                                              16    7355
NP_005867                                                              16    7355
NP_060506                                                              16    7355
XP_006726598                                                           16    7355
XP_005268084                                                           16    7355
XP_006720250                                                           16    7355
XP_006715611                                                           16    7355
XP_006712256                                                           16    7355
XP_005246298                                                           16    7355
XP_005246297                                                           16    7355
XP_005246299                                                           16    7355
XP_005246296                                                           16    7355
XP_006712254                                                           16    7355
XP_005246295                                                           16    7355
XP_006712253                                                           16    7355
XP_006712252                                                           16    7355
XP_005246294                                                           16    7355
XP_006712251                                                           16    7355
XP_005246293                                                           16    7355
XP_005246292                                                           16    7355
XP_006712250                                                           16    7355
NP_004122                                                              15    9605
NP_733468                                                              15    9605
NP_653091                                                              15    9605
NP_004230                                                              15    9605
NP_853514                                                              15    9605
NP_071418                                                              15    9605
XP_005268271                                                           15    9605
XP_005268270                                                           15    9605
XP_006720384                                                           15    9605
XP_005268418                                                           15    9605
XP_005268417                                                           15    9605
XP_005268416                                                           15    9605
XP_005248295                                                           15    9605
XP_006714098                                                           15    9605
XP_005247756                                                           15    9605
XP_005247755                                                           15    9605
NP_061161                                                              15    9605
NP_009208                                                              15    9605
NP_072093                                                              15    9605
>NP_004295
          Length = 1620

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLWARKSLQ 9
           LLWA KSLQ
Sbjct: 889 LLWAGKSLQ 897
>NP_001013679
          Length = 385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLWARKS 7
           +LWARKS
Sbjct: 312 ILWARKS 318
>NP_667338
          Length = 1308

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            +LWARK  Q
Sbjct: 1211 MLWARKRKQ 1219
>NP_001159608
          Length = 1228

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            +LWARK  Q
Sbjct: 1131 MLWARKRKQ 1139
>XP_006713923
          Length = 1228

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            +LWARK  Q
Sbjct: 1131 MLWARKRKQ 1139
>XP_006713922
          Length = 1262

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            +LWARK  Q
Sbjct: 1211 MLWARKRKQ 1219
>NP_075561
          Length = 3197

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            L WARK +Q
Sbjct: 1215 LRWARKVMQ 1223
>NP_612154
          Length = 1125

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLWARKSLQ 9
           LLW  KSL+
Sbjct: 713 LLWTPKSLE 721
>NP_060876
          Length = 5412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            LLW  KSL+
Sbjct: 5000 LLWTPKSLE 5008
>NP_004523
          Length = 1176

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLWARKSLQ 9
           LLW  KSL+
Sbjct: 764 LLWTPKSLE 772
>XP_005248410
          Length = 2132

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLWARKSLQ 9
           L WARK +Q
Sbjct: 96  LRWARKVMQ 104
>XP_006714553
          Length = 2792

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            L WARK +Q
Sbjct: 1215 LRWARKVMQ 1223
>XP_005248407
          Length = 3208

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            L WARK +Q
Sbjct: 1172 LRWARKVMQ 1180
>XP_005248406
          Length = 3214

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            L WARK +Q
Sbjct: 1215 LRWARKVMQ 1223
>XP_005248404
          Length = 3250

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            L WARK +Q
Sbjct: 1215 LRWARKVMQ 1223
>XP_005248403
          Length = 3250

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            L WARK +Q
Sbjct: 1215 LRWARKVMQ 1223
>XP_006714552
          Length = 3251

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            L WARK +Q
Sbjct: 1215 LRWARKVMQ 1223
>XP_005248402
          Length = 3251

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLWARKSLQ 9
            L WARK +Q
Sbjct: 1215 LRWARKVMQ 1223
>NP_932349
          Length = 232

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  WARKSLQ 9
          WARKS++
Sbjct: 12 WARKSVR 18
>NP_003025
          Length = 356

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LLWARKS 7
           LLW+RK+
Sbjct: 199 LLWSRKT 205
>XP_005253526
          Length = 213

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLWARKS 7
          LLW+RK+
Sbjct: 56 LLWSRKT 62
>NP_004761
          Length = 911

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   WARKSL 8
           WARK+L
Sbjct: 494 WARKAL 499
>XP_006716546
          Length = 741

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   WARKSL 8
           WARK+L
Sbjct: 324 WARKAL 329
>XP_005265796
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LWARKSLQ 9
           LW  KSLQ
Sbjct: 167 LWKLKSLQ 174
>NP_001019782
          Length = 880

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LWARKSLQ 9
           LW  KSLQ
Sbjct: 167 LWKLKSLQ 174
>NP_001186068
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LWARKSLQ 9
           LW ++SLQ
Sbjct: 528 LWRQESLQ 535
>NP_067032
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LWARKSLQ 9
           LW ++SLQ
Sbjct: 528 LWRQESLQ 535
>NP_001186067
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LWARKSLQ 9
           LW ++SLQ
Sbjct: 528 LWRQESLQ 535
>NP_619639
          Length = 4074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LWARKSLQ 9
            LW  +SLQ
Sbjct: 2630 LWINRSLQ 2637
>NP_733842
          Length = 3396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LWARKSLQ 9
            LW  +SLQ
Sbjct: 2630 LWINRSLQ 2637
>NP_003004
          Length = 295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLWARKSLQ 9
           +LW + SLQ
Sbjct: 236 VLWLKDSLQ 244
>NP_009041
          Length = 2627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LWARKSLQ 9
            LW R S+Q
Sbjct: 2579 LWERPSMQ 2586
>NP_002935
          Length = 2347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   LLWARKS 7
           L+WA+K+
Sbjct: 344 LIWAKKA 350
>NP_001181
          Length = 392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  LWARKSL 8
          +WARK L
Sbjct: 9  IWARKLL 15
>NP_005863
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLWARKSLQ 9
           L W RK++Q
Sbjct: 163 LNWQRKNMQ 171
>NP_005867
          Length = 3267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3204 WSRPSLQ 3210
>NP_060506
          Length = 2078

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   WARKSLQ 9
           W +KSLQ
Sbjct: 770 WFKKSLQ 776
>XP_006726598
          Length = 885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  WARKSLQ 9
          WA KSL+
Sbjct: 62 WAAKSLE 68
>XP_005268084
          Length = 2627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LWARKSLQ 9
            LW R S+Q
Sbjct: 2579 LWERPSMQ 2586
>XP_006720250
          Length = 2077

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   WARKSLQ 9
           W +KSLQ
Sbjct: 769 WFKKSLQ 775
>XP_006715611
          Length = 2342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   LLWARKS 7
           L+WA+K+
Sbjct: 353 LIWAKKA 359
>XP_006712256
          Length = 2418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 2355 WSRPSLQ 2361
>XP_005246298
          Length = 2418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 2355 WSRPSLQ 2361
>XP_005246297
          Length = 2418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 2355 WSRPSLQ 2361
>XP_005246299
          Length = 2480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 2417 WSRPSLQ 2423
>XP_005246296
          Length = 2475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 2412 WSRPSLQ 2418
>XP_006712254
          Length = 2475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 2412 WSRPSLQ 2418
>XP_005246295
          Length = 3114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3051 WSRPSLQ 3057
>XP_006712253
          Length = 3117

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3054 WSRPSLQ 3060
>XP_006712252
          Length = 3163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3100 WSRPSLQ 3106
>XP_005246294
          Length = 3173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3110 WSRPSLQ 3116
>XP_006712251
          Length = 3176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3113 WSRPSLQ 3119
>XP_005246293
          Length = 3206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3143 WSRPSLQ 3149
>XP_005246292
          Length = 3208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3145 WSRPSLQ 3151
>XP_006712250
          Length = 3248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    WARKSLQ 9
            W+R SLQ
Sbjct: 3185 WSRPSLQ 3191
>NP_004122
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LLWARKSLQ 9
          ++W +KSL+
Sbjct: 39 MIWDQKSLK 47
>NP_733468
          Length = 2342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   LWARKSL 8
           +W RKS+
Sbjct: 873 IWGRKSV 879
>NP_653091
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   LWARKSL 8
           +W RKS+
Sbjct: 847 IWGRKSV 853
>NP_004230
          Length = 1979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LLWARKSL 8
           L WA+K L
Sbjct: 725 LCWAKKRL 732
>NP_853514
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLWARKSLQ 9
           ++WARK  Q
Sbjct: 715 VVWARKKDQ 723
>NP_071418
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   WARKSL 8
           W RKSL
Sbjct: 214 WPRKSL 219
>XP_005268271
          Length = 1537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LLWARKSL 8
           L WA+K L
Sbjct: 283 LCWAKKRL 290
>XP_005268270
          Length = 1950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LLWARKSL 8
           L WA+K L
Sbjct: 696 LCWAKKRL 703
>XP_006720384
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   LLWARKSL 8
           L WA+K L
Sbjct: 724 LCWAKKRL 731
>XP_005268418
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   WARKSL 8
           W RKSL
Sbjct: 339 WIRKSL 344
>XP_005268417
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   WARKSL 8
           W RKSL
Sbjct: 339 WIRKSL 344
>XP_005268416
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   WARKSL 8
           W RKSL
Sbjct: 345 WIRKSL 350
>XP_005248295
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   LLWARKSLQ 9
           + W RK+L+
Sbjct: 392 IAWLRKALE 400
>XP_006714098
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   LWARKSLQ 9
           +W+ KS+Q
Sbjct: 194 IWSDKSIQ 201
>XP_005247756
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   WARKSL 8
           W RKSL
Sbjct: 214 WPRKSL 219
>XP_005247755
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   WARKSL 8
           W RKSL
Sbjct: 214 WPRKSL 219
>NP_061161
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3   WARKSL 8
           W RKSL
Sbjct: 339 WIRKSL 344
>NP_009208
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   LLWARKSLQ 9
           + W RK+L+
Sbjct: 392 IAWLRKALE 400
>NP_072093
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   LWARKS 7
           +WARK+
Sbjct: 459 MWARKN 464
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.130    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 632,514
Number of extensions: 637
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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