Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065681                                                              18    1482
NP_066124                                                              18    1482
XP_006717999                                                           18    1482
NP_001177645                                                           17    4312
NP_004936                                                              17    4312
NP_001005361                                                           17    4312
NP_001005360                                                           17    4312
NP_001005362                                                           17    4312
NP_001243474                                                           17    4312
NP_115822                                                              17    4312
XP_006714785                                                           17    4312
NP_115821                                                              17    4312
NP_001010893                                                           17    4312
NP_001160060                                                           16    5631
NP_001750                                                              16    7355
NP_001257457                                                           16    7355
NP_060080                                                              16    7355
NP_001257458                                                           16    7355
NP_001257459                                                           16    7355
XP_006720643                                                           16    7355
XP_006720642                                                           16    7355
XP_005254536                                                           16    7355
XP_006720641                                                           16    7355
XP_006720640                                                           16    7355
XP_005254533                                                           16    7355
XP_005254532                                                           16    7355
XP_006720639                                                           16    7355
XP_005254530                                                           16    7355
XP_006720638                                                           16    7355
XP_005253870                                                           16    7355
NP_001166879                                                           15    9605
NP_001933                                                              15    9605
NP_000433                                                              15    9605
NP_036596                                                              15    9605
NP_001161814                                                           15    9605
NP_001234919                                                           15    9605
NP_976230                                                              15    9605
NP_001234918                                                           15    9605
NP_001265436                                                           15    9605
NP_001234917                                                           15    9605
NP_057573                                                              15    9605
NP_061819                                                              15    9605
NP_001139131                                                           15    9605
NP_001161811                                                           15    9605
NP_001159590                                                           15    9605
NP_001002010                                                           15    9605
NP_001002009                                                           15    9605
NP_976231                                                              15    9605
NP_976229                                                              15    9605
NP_001008747                                                           15    9605
NP_689787                                                              15    9605
NP_001161813                                                           15    9605
NP_001161812                                                           15    9605
XP_005276940                                                           15    9605
XP_005276939                                                           15    9605
XP_005276938                                                           15    9605
XP_005276937                                                           15    9605
XP_006722008                                                           15    9605
XP_006722007                                                           15    9605
XP_006720211                                                           15    9605
XP_005267707                                                           15    9605
XP_005267706                                                           15    9605
XP_005267705                                                           15    9605
XP_005267704                                                           15    9605
XP_005267703                                                           15    9605
XP_005263249                                                           15    9605
XP_006714356                                                           15    9605
NP_940897                                                              15    9605
NP_848656                                                              15    9605
NP_005921                                                              15    9605
>NP_065681
          Length = 1072

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLVTVEESY 9
           LLVTVE SY
Sbjct: 500 LLVTVEGSY 508
>NP_066124
          Length = 1114

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLVTVEESY 9
           LLVTVE SY
Sbjct: 500 LLVTVEGSY 508
>XP_006717999
          Length = 1207

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLVTVEESY 9
           LLVTVE SY
Sbjct: 593 LLVTVEGSY 601
>NP_001177645
          Length = 869

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLVTVEESY 9
           LL+ +E+SY
Sbjct: 477 LLIDIEQSY 485
>NP_004936
          Length = 866

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLVTVEESY 9
           LL+ +E+SY
Sbjct: 477 LLIDIEQSY 485
>NP_001005361
          Length = 870

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLVTVEESY 9
           LL+ +E+SY
Sbjct: 477 LLIDIEQSY 485
>NP_001005360
          Length = 870

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLVTVEESY 9
           LL+ +E+SY
Sbjct: 477 LLIDIEQSY 485
>NP_001005362
          Length = 866

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLVTVEESY 9
           LL+ +E+SY
Sbjct: 477 LLIDIEQSY 485
>NP_001243474
          Length = 1140

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VTVEESY 9
          VTV+ESY
Sbjct: 42 VTVQESY 48
>NP_115822
          Length = 1140

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VTVEESY 9
          VTV+ESY
Sbjct: 42 VTVQESY 48
>XP_006714785
          Length = 1109

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VTVEESY 9
          VTV+ESY
Sbjct: 42 VTVQESY 48
>NP_115821
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VTVEESY 9
          VTV+ESY
Sbjct: 36 VTVQESY 42
>NP_001010893
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LLVTVEES 8
          LLVT+EE+
Sbjct: 12 LLVTIEEA 19
>NP_001160060
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VTVEESY 9
           VTVEE Y
Sbjct: 396 VTVEEGY 402
>NP_001750
          Length = 289

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LVTVEESY 9
          L+T+EE Y
Sbjct: 30 LLTIEERY 37
>NP_001257457
          Length = 995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 328 IVTVGESY 335
>NP_060080
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 328 IVTVGESY 335
>NP_001257458
          Length = 985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 328 IVTVGESY 335
>NP_001257459
          Length = 994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 328 IVTVGESY 335
>XP_006720643
          Length = 1003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 328 IVTVGESY 335
>XP_006720642
          Length = 1003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 328 IVTVGESY 335
>XP_005254536
          Length = 1003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 328 IVTVGESY 335
>XP_006720641
          Length = 1008

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 351 IVTVGESY 358
>XP_006720640
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 351 IVTVGESY 358
>XP_005254533
          Length = 1016

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 351 IVTVGESY 358
>XP_005254532
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 351 IVTVGESY 358
>XP_006720639
          Length = 1018

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 351 IVTVGESY 358
>XP_005254530
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 351 IVTVGESY 358
>XP_006720638
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           +VTV ESY
Sbjct: 351 IVTVGESY 358
>XP_005253870
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LVTVEESY 9
          L+T+EE Y
Sbjct: 30 LLTIEERY 37
>NP_001166879
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VTVEESY 9
           VTV ESY
Sbjct: 981 VTVTESY 987
>NP_001933
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VTVEESY 9
           VTV ESY
Sbjct: 835 VTVTESY 841
>NP_000433
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           LVTV ES+
Sbjct: 226 LVTVTESF 233
>NP_036596
          Length = 1013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VTVEESY 9
           +TV ESY
Sbjct: 492 ITVSESY 498
>NP_001161814
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLVTVEES 8
           LLVTVE++
Sbjct: 395 LLVTVEKA 402
>NP_001234919
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 325 LTVEENY 331
>NP_976230
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 400 LTVEENY 406
>NP_001234918
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 405 LTVEENY 411
>NP_001265436
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 402 LTVEENY 408
>NP_001234917
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 371 LTVEENY 377
>NP_057573
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           ++TVEE Y
Sbjct: 100 VLTVEEKY 107
>NP_061819
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLVTVEE 7
           +LVTVEE
Sbjct: 335 VLVTVEE 341
>NP_001139131
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 402 LTVEENY 408
>NP_001161811
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLVTVEES 8
           LLVTVE++
Sbjct: 558 LLVTVEKA 565
>NP_001159590
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LVTVEESY 9
          ++TVEE Y
Sbjct: 88 VLTVEEKY 95
>NP_001002010
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           ++TVEE Y
Sbjct: 139 VLTVEEKY 146
>NP_001002009
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           ++TVEE Y
Sbjct: 100 VLTVEEKY 107
>NP_976231
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 371 LTVEENY 377
>NP_976229
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 388 LTVEENY 394
>NP_001008747
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 402 LTVEENY 408
>NP_689787
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLVTVEES 8
           LLVTVE++
Sbjct: 560 LLVTVEKA 567
>NP_001161813
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLVTVEES 8
           LLVTVE++
Sbjct: 491 LLVTVEKA 498
>NP_001161812
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLVTVEES 8
           LLVTVE++
Sbjct: 547 LLVTVEKA 554
>XP_005276940
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           LVTV ES+
Sbjct: 226 LVTVTESF 233
>XP_005276939
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           LVTV ES+
Sbjct: 226 LVTVTESF 233
>XP_005276938
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           LVTV ES+
Sbjct: 226 LVTVTESF 233
>XP_005276937
          Length = 727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           LVTV ES+
Sbjct: 226 LVTVTESF 233
>XP_006722008
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           LVTV ES+
Sbjct: 226 LVTVTESF 233
>XP_006722007
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LVTVEESY 9
           LVTV ES+
Sbjct: 226 LVTVTESF 233
>XP_006720211
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 371 LTVEENY 377
>XP_005267707
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 376 LTVEENY 382
>XP_005267706
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 393 LTVEENY 399
>XP_005267705
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 394 LTVEENY 400
>XP_005267704
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 395 LTVEENY 401
>XP_005267703
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 399 LTVEENY 405
>XP_005263249
          Length = 727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VTVEESY 9
           +TV ESY
Sbjct: 206 ITVSESY 212
>XP_006714356
          Length = 964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VTVEESY 9
           +TV ESY
Sbjct: 443 ITVSESY 449
>NP_940897
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 402 LTVEENY 408
>NP_848656
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 402 LTVEENY 408
>NP_005921
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VTVEESY 9
           +TVEE+Y
Sbjct: 400 LTVEENY 406
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.130    0.312 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 516,663
Number of extensions: 986
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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