Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_054742                                                              16    5631
NP_004648                                                              16    5631
NP_001240775                                                           16    7355
NP_001491                                                              16    7355
XP_006715129                                                           16    7355
NP_001034484                                                           15    9605
NP_612350                                                              15    9605
NP_001180382                                                           15    9605
NP_001180460                                                           15    9605
NP_005133                                                              15    9605
NP_004718                                                              15    9605
XP_005254838                                                           15    9605
XP_006720832                                                           15    9605
XP_006720831                                                           15    9605
XP_005254837                                                           15    9605
XP_006720830                                                           15    9605
XP_006720829                                                           15    9605
XP_005254836                                                           15    9605
XP_006720828                                                           15    9605
XP_006720827                                                           15    9605
XP_005254835                                                           15    9605
XP_006719743                                                           15    9605
XP_006719742                                                           15    9605
XP_006719741                                                           15    9605
XP_005254043                                                           15    9605
XP_005254042                                                           15    9605
XP_005273967                                                           15    9605
XP_006716866                                                           15    9605
XP_006716865                                                           15    9605
XP_006716864                                                           15    9605
XP_005251556                                                           15    9605
XP_006716863                                                           15    9605
XP_006716862                                                           15    9605
XP_006716861                                                           15    9605
XP_006716860                                                           15    9605
XP_006716859                                                           15    9605
XP_006716858                                                           15    9605
XP_006715232                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
NP_008955                                                              15    9605
>NP_054742
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TYQASTS 9
           TY+ASTS
Sbjct: 125 TYKASTS 131
>NP_004648
          Length = 425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTYQASTS 9
           L  YQASTS
Sbjct: 100 LSKYQASTS 108
>NP_001240775
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   YQASTS 9
           YQASTS
Sbjct: 121 YQASTS 126
>NP_001491
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   YQASTS 9
           YQASTS
Sbjct: 151 YQASTS 156
>XP_006715129
          Length = 290

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   YQASTS 9
           YQASTS
Sbjct: 151 YQASTS 156
>NP_001034484
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 256 TYQHSTS 262
>NP_612350
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTYQASTS 9
           LT+ ASTS
Sbjct: 235 LTFPASTS 242
>NP_001180382
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTYQASTS 9
           LT+ ASTS
Sbjct: 292 LTFPASTS 299
>NP_001180460
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTYQASTS 9
           LT+ ASTS
Sbjct: 327 LTFPASTS 334
>NP_005133
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLTYQASTS 9
          LLTYQ  +S
Sbjct: 74 LLTYQLMSS 82
>NP_004718
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_005254838
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_006720832
          Length = 935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_006720831
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_005254837
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_006720830
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_006720829
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_005254836
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_006720828
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_006720827
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_005254835
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTYQASTS 9
           LTY  STS
Sbjct: 151 LTYYTSTS 158
>XP_006719743
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTYQASTS 9
           LT+ ASTS
Sbjct: 235 LTFPASTS 242
>XP_006719742
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTYQASTS 9
           LT+ ASTS
Sbjct: 326 LTFPASTS 333
>XP_006719741
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTYQASTS 9
           LT+ ASTS
Sbjct: 354 LTFPASTS 361
>XP_005254043
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTYQASTS 9
           LT+ ASTS
Sbjct: 361 LTFPASTS 368
>XP_005254042
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTYQASTS 9
           LT+ ASTS
Sbjct: 384 LTFPASTS 391
>XP_005273967
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLTYQASTS 9
          LLTYQ  +S
Sbjct: 49 LLTYQLMSS 57
>XP_006716866
          Length = 225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 147 TYQHSTS 153
>XP_006716865
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 191 TYQHSTS 197
>XP_006716864
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 205 TYQHSTS 211
>XP_005251556
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 248 TYQHSTS 254
>XP_006716863
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 295 TYQHSTS 301
>XP_006716862
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 314 TYQHSTS 320
>XP_006716861
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 328 TYQHSTS 334
>XP_006716860
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 328 TYQHSTS 334
>XP_006716859
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 328 TYQHSTS 334
>XP_006716858
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TYQASTS 9
           TYQ STS
Sbjct: 328 TYQHSTS 334
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1813 ILTYQVQT 1820
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1487 ILTYQVQT 1494
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1813 ILTYQVQT 1820
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1839 ILTYQVQT 1846
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1846 ILTYQVQT 1853
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1853 ILTYQVQT 1860
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1886 ILTYQVQT 1893
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1929 ILTYQVQT 1936
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 1991 ILTYQVQT 1998
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 2003 ILTYQVQT 2010
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    LLTYQAST 8
            +LTYQ  T
Sbjct: 2024 ILTYQVQT 2031
>NP_008955
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LLTYQAS 7
           LLTY AS
Sbjct: 118 LLTYMAS 124
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.110    0.261 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 356,638
Number of extensions: 361
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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