Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001092094                                                           17    2528
NP_000372                                                              17    2528
NP_150632                                                              17    2528
NP_001180206                                                           17    2528
NP_150631                                                              17    2528
XP_006724556                                                           17    2528
XP_005274594                                                           17    2528
XP_005274593                                                           17    2528
XP_006724555                                                           17    2528
NP_056142                                                              17    3301
NP_055952                                                              17    3301
XP_005250906                                                           17    3301
XP_006711311                                                           17    3301
XP_005245106                                                           17    3301
NP_001138729                                                           17    4312
NP_001107654                                                           17    4312
NP_001138730                                                           17    4312
NP_057207                                                              17    4312
NP_001138728                                                           17    4312
NP_001171616                                                           17    4312
NP_001171617                                                           17    4312
NP_055056                                                              17    4312
NP_940684                                                              17    4312
NP_849144                                                              17    4312
XP_006719506                                                           17    4312
XP_006719505                                                           17    4312
XP_006719504                                                           17    4312
XP_006719503                                                           17    4312
XP_005269006                                                           17    4312
XP_006719502                                                           17    4312
XP_005269004                                                           17    4312
XP_005269005                                                           17    4312
XP_005269003                                                           17    4312
XP_005269000                                                           17    4312
XP_005269001                                                           17    4312
XP_005269002                                                           17    4312
XP_006719501                                                           17    4312
XP_005252698                                                           17    4312
XP_006713663                                                           17    4312
XP_006713660                                                           17    4312
XP_005247434                                                           17    4312
XP_006713659                                                           17    4312
NP_005196                                                              16    5631
NP_001177957                                                           16    7355
NP_036602                                                              16    7355
NP_777576                                                              16    7355
NP_001182053                                                           16    7355
XP_006715974                                                           16    7355
NP_002522                                                              16    7355
NP_065853                                                              15    9605
NP_002982                                                              15    9605
NP_001009984                                                           15    9605
NP_057063                                                              15    9605
NP_620154                                                              15    9605
NP_075463                                                              15    9605
NP_004821                                                              15    9605
NP_001257451                                                           15    9605
NP_001257450                                                           15    9605
NP_660348                                                              15    9605
XP_006724802                                                           15    9605
XP_006724801                                                           15    9605
XP_005262448                                                           15    9605
XP_005262447                                                           15    9605
XP_005260744                                                           15    9605
XP_006723620                                                           15    9605
XP_006723619                                                           15    9605
XP_005260741                                                           15    9605
XP_006723581                                                           15    9605
XP_006723580                                                           15    9605
XP_006719812                                                           15    9605
XP_005271684                                                           15    9605
XP_005267280                                                           15    9605
NP_999875                                                              15    9605
NP_110382                                                              15    9605
>NP_001092094
          Length = 667

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 648 LTIITGLP 655
>NP_000372
          Length = 667

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 648 LTIITGLP 655
>NP_150632
          Length = 667

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 648 LTIITGLP 655
>NP_001180206
          Length = 667

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 648 LTIITGLP 655
>NP_150631
          Length = 629

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 610 LTIITGLP 617
>XP_006724556
          Length = 680

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 661 LTIITGLP 668
>XP_005274594
          Length = 718

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 699 LTIITGLP 706
>XP_005274593
          Length = 718

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 699 LTIITGLP 706
>XP_006724555
          Length = 718

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LTIIT LP
Sbjct: 699 LTIITGLP 706
>NP_056142
          Length = 1016

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           ++TIIT LP
Sbjct: 969 MVTIITGLP 977
>NP_055952
          Length = 821

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TIITALP 9
           TI+TALP
Sbjct: 451 TIVTALP 457
>XP_005250906
          Length = 785

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TIITALP 9
           TI+TALP
Sbjct: 415 TIVTALP 421
>XP_006711311
          Length = 950

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           ++TIIT LP
Sbjct: 903 MVTIITGLP 911
>XP_005245106
          Length = 970

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           ++TIIT LP
Sbjct: 923 MVTIITGLP 931
>NP_001138729
          Length = 336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 253 LLEIITGLP 261
>NP_001107654
          Length = 460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 377 LLEIITGLP 385
>NP_001138730
          Length = 336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 253 LLEIITGLP 261
>NP_057207
          Length = 460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 377 LLEIITGLP 385
>NP_001138728
          Length = 336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 253 LLEIITGLP 261
>NP_001171616
          Length = 650

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LT+ITA P
Sbjct: 161 LTVITAAP 168
>NP_001171617
          Length = 602

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LT+ITA P
Sbjct: 113 LTVITAAP 120
>NP_055056
          Length = 288

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LLTI  ALP
Sbjct: 218 LLTIYAALP 226
>NP_940684
          Length = 254

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LLTI  ALP
Sbjct: 184 LLTIYAALP 192
>NP_849144
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LTIITALP 9
            LT+ITA P
Sbjct: 2134 LTVITAAP 2141
>XP_006719506
          Length = 257

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 174 LLEIITGLP 182
>XP_006719505
          Length = 257

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 174 LLEIITGLP 182
>XP_006719504
          Length = 257

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 174 LLEIITGLP 182
>XP_006719503
          Length = 257

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 174 LLEIITGLP 182
>XP_005269006
          Length = 336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 253 LLEIITGLP 261
>XP_006719502
          Length = 336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 253 LLEIITGLP 261
>XP_005269004
          Length = 336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 253 LLEIITGLP 261
>XP_005269005
          Length = 336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 253 LLEIITGLP 261
>XP_005269003
          Length = 460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 377 LLEIITGLP 385
>XP_005269000
          Length = 460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 377 LLEIITGLP 385
>XP_005269001
          Length = 460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 377 LLEIITGLP 385
>XP_005269002
          Length = 460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 377 LLEIITGLP 385
>XP_006719501
          Length = 460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL IIT LP
Sbjct: 377 LLEIITGLP 385
>XP_005252698
          Length = 252

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LLTI  ALP
Sbjct: 182 LLTIYAALP 190
>XP_006713663
          Length = 602

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LT+ITA P
Sbjct: 113 LTVITAAP 120
>XP_006713660
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LTIITALP 9
            LT+ITA P
Sbjct: 2134 LTVITAAP 2141
>XP_005247434
          Length = 2623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LTIITALP 9
            LT+ITA P
Sbjct: 2134 LTVITAAP 2141
>XP_006713659
          Length = 2695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LTIITALP 9
            LT+ITA P
Sbjct: 2206 LTVITAAP 2213
>NP_005196
          Length = 97

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLTIITALP 9
          LLT + ALP
Sbjct: 30 LLTFVLALP 38
>NP_001177957
          Length = 859

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL I+T LP
Sbjct: 143 LLEILTVLP 151
>NP_036602
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL I+T LP
Sbjct: 143 LLEILTVLP 151
>NP_777576
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLTIITALP 9
            LLT+ T LP
Sbjct: 1451 LLTVDTGLP 1459
>NP_001182053
          Length = 239

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           LLT++ A+P
Sbjct: 219 LLTLLQAIP 227
>XP_006715974
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLTIITALP 9
           LL I+T LP
Sbjct: 143 LLEILTVLP 151
>NP_002522
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           LLT++ A+P
Sbjct: 113 LLTLLLAMP 121
>NP_065853
          Length = 1117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           L+T+I +LP
Sbjct: 868 LVTVIPSLP 876
>NP_002982
          Length = 119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLTIITAL 8
          L+TI+T+L
Sbjct: 4  LMTIVTSL 11
>NP_001009984
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           +++I+T LP
Sbjct: 748 IISIVTGLP 756
>NP_057063
          Length = 1365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    IITALP 9
            IITALP
Sbjct: 1158 IITALP 1163
>NP_620154
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LTIITALP 9
           LTI T LP
Sbjct: 248 LTICTTLP 255
>NP_075463
          Length = 3013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLTIITAL 8
           L+TIIT L
Sbjct: 430 LITIITTL 437
>NP_004821
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    IITALP 9
            IITALP
Sbjct: 1152 IITALP 1157
>NP_001257451
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    IITALP 9
            IITALP
Sbjct: 1152 IITALP 1157
>NP_001257450
          Length = 1359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    IITALP 9
            IITALP
Sbjct: 1152 IITALP 1157
>NP_660348
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LT++ ALP
Sbjct: 169 LTVVGALP 176
>XP_006724802
          Length = 237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LT++ ALP
Sbjct: 169 LTVVGALP 176
>XP_006724801
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LT++ ALP
Sbjct: 169 LTVVGALP 176
>XP_005262448
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LT++ ALP
Sbjct: 169 LTVVGALP 176
>XP_005262447
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           LT++ ALP
Sbjct: 169 LTVVGALP 176
>XP_005260744
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           +++I+T LP
Sbjct: 163 IISIVTGLP 171
>XP_006723620
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           +++I+T LP
Sbjct: 748 IISIVTGLP 756
>XP_006723619
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           +++I+T LP
Sbjct: 722 IISIVTGLP 730
>XP_005260741
          Length = 1176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           +++I+T LP
Sbjct: 747 IISIVTGLP 755
>XP_006723581
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           L IITA+P
Sbjct: 132 LCIITAVP 139
>XP_006723580
          Length = 262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTIITALP 9
           L IITA+P
Sbjct: 144 LCIITAVP 151
>XP_006719812
          Length = 3019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLTIITAL 8
           L+TIIT L
Sbjct: 427 LITIITTL 434
>XP_005271684
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLTIITALP 9
           L+T+I +LP
Sbjct: 868 LVTVIPSLP 876
>XP_005267280
          Length = 1374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    IITALP 9
            IITALP
Sbjct: 1158 IITALP 1163
>NP_999875
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LLTIITAL 8
          LLT+ TAL
Sbjct: 12 LLTVATAL 19
>NP_110382
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   IITALP 9
           IITALP
Sbjct: 96  IITALP 101
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.149    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 406,946
Number of extensions: 710
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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