Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_612449                                                              18    1135
NP_733751                                                              18    1935
XP_006716142                                                           18    1935
XP_005250088                                                           18    1935
XP_006716141                                                           18    1935
XP_005250085                                                           18    1935
XP_006716140                                                           18    1935
XP_005250084                                                           18    1935
XP_005250083                                                           18    1935
XP_005250082                                                           18    1935
NP_001271215                                                           17    3301
NP_001271214                                                           17    3301
NP_066973                                                              16    5631
NP_001171545                                                           16    5631
XP_005268816                                                           16    5631
XP_005268815                                                           16    5631
XP_005268814                                                           16    5631
XP_005268813                                                           16    5631
XP_005268812                                                           16    5631
XP_005268811                                                           16    5631
NP_001005490                                                           16    7355
NP_116277                                                              16    7355
XP_006717372                                                           16    7355
XP_006717371                                                           16    7355
XP_005271185                                                           16    7355
XP_005271183                                                           16    7355
XP_005271182                                                           16    7355
NP_112174                                                              16    7355
NP_073611                                                              16    7355
NP_001124456                                                           15    9605
NP_001124459                                                           15    9605
NP_001124455                                                           15    9605
NP_001124450                                                           15    9605
NP_001124449                                                           15    9605
NP_001124453                                                           15    9605
NP_004235                                                              15    9605
NP_001252516                                                           15    9605
NP_981961                                                              15    9605
NP_001239312                                                           15    9605
NP_001278233                                                           15    9605
NP_001263629                                                           15    9605
NP_612202                                                              15    9605
NP_008944                                                              15    9605
NP_056121                                                              15    9605
NP_001073865                                                           15    9605
NP_777593                                                              15    9605
NP_955452                                                              15    9605
NP_001074003                                                           15    9605
XP_005276595                                                           15    9605
XP_006722199                                                           15    9605
XP_005257785                                                           15    9605
XP_005254452                                                           15    9605
XP_005254451                                                           15    9605
XP_005253586                                                           15    9605
XP_005253585                                                           15    9605
XP_006717910                                                           15    9605
XP_005269884                                                           15    9605
XP_006717909                                                           15    9605
XP_005269883                                                           15    9605
XP_006717905                                                           15    9605
XP_006717902                                                           15    9605
XP_006717901                                                           15    9605
XP_006717900                                                           15    9605
XP_005250818                                                           15    9605
XP_005250817                                                           15    9605
XP_006713543                                                           15    9605
XP_005264642                                                           15    9605
XP_005264641                                                           15    9605
XP_005270747                                                           15    9605
XP_006710574                                                           15    9605
XP_005270746                                                           15    9605
NP_001129475                                                           15    9605
NP_115510                                                              15    9605
YP_003024032                                                           15    9605
>NP_612449
          Length = 673

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSSSLAPT 9
           LSSSLAPT
Sbjct: 371 LSSSLAPT 378
>NP_733751
          Length = 4911

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1411 LLSSSSAPT 1419
>XP_006716142
          Length = 4927

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1412 LLSSSSAPT 1420
>XP_005250088
          Length = 4928

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1412 LLSSSSAPT 1420
>XP_006716141
          Length = 4959

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1412 LLSSSSAPT 1420
>XP_005250085
          Length = 4979

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1412 LLSSSSAPT 1420
>XP_006716140
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1412 LLSSSSAPT 1420
>XP_005250084
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1412 LLSSSSAPT 1420
>XP_005250083
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1411 LLSSSSAPT 1419
>XP_005250082
          Length = 4983

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LLSSSLAPT 9
            LLSSS APT
Sbjct: 1412 LLSSSSAPT 1420
>NP_001271215
          Length = 939

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SSSLAPT 9
          SSSLAPT
Sbjct: 36 SSSLAPT 42
>NP_001271214
          Length = 1006

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSSLAPT 9
           SSSLAPT
Sbjct: 103 SSSLAPT 109
>NP_066973
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L+SSS +PT
Sbjct: 350 LVSSSFSPT 358
>NP_001171545
          Length = 1061

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L+SSS +PT
Sbjct: 350 LVSSSFSPT 358
>XP_005268816
          Length = 1062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L+SSS +PT
Sbjct: 351 LVSSSFSPT 359
>XP_005268815
          Length = 1077

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L+SSS +PT
Sbjct: 351 LVSSSFSPT 359
>XP_005268814
          Length = 1102

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L+SSS +PT
Sbjct: 376 LVSSSFSPT 384
>XP_005268813
          Length = 1114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L+SSS +PT
Sbjct: 403 LVSSSFSPT 411
>XP_005268812
          Length = 1128

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L+SSS +PT
Sbjct: 402 LVSSSFSPT 410
>XP_005268811
          Length = 1129

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L+SSS +PT
Sbjct: 403 LVSSSFSPT 411
>NP_001005490
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSSSLAP 8
           LLS+S+AP
Sbjct: 274 LLSTSVAP 281
>NP_116277
          Length = 1860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSSLAPT 9
           LSSS APT
Sbjct: 487 LSSSPAPT 494
>XP_006717372
          Length = 1842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSSLAPT 9
           LSSS APT
Sbjct: 487 LSSSPAPT 494
>XP_006717371
          Length = 1842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSSLAPT 9
           LSSS APT
Sbjct: 487 LSSSPAPT 494
>XP_005271185
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSSSLAP 8
           +LSS+LAP
Sbjct: 360 VLSSTLAP 367
>XP_005271183
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSSSLAP 8
           +LSS+LAP
Sbjct: 360 VLSSTLAP 367
>XP_005271182
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSSSLAP 8
           +LSS+LAP
Sbjct: 360 VLSSTLAP 367
>NP_112174
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSSLAPT 9
           SSSL+PT
Sbjct: 317 SSSLSPT 323
>NP_073611
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSSSLAP 8
           +LSS+LAP
Sbjct: 360 VLSSTLAP 367
>NP_001124456
          Length = 2088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SSLAPT 9
            SSLAPT
Sbjct: 1463 SSLAPT 1468
>NP_001124459
          Length = 2119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SSLAPT 9
            SSLAPT
Sbjct: 1494 SSLAPT 1499
>NP_001124455
          Length = 2102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SSLAPT 9
            SSLAPT
Sbjct: 1477 SSLAPT 1482
>NP_001124450
          Length = 2101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SSLAPT 9
            SSLAPT
Sbjct: 1476 SSLAPT 1481
>NP_001124449
          Length = 2087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SSLAPT 9
            SSLAPT
Sbjct: 1462 SSLAPT 1467
>NP_001124453
          Length = 2118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SSLAPT 9
            SSLAPT
Sbjct: 1493 SSLAPT 1498
>NP_004235
          Length = 1156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSSLAPT 9
           SSSL PT
Sbjct: 695 SSSLGPT 701
>NP_001252516
          Length = 157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LLSSSLAPT 9
          LLSSS  PT
Sbjct: 77 LLSSSNPPT 85
>NP_981961
          Length = 1121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSSLAPT 9
           SSSL PT
Sbjct: 695 SSSLGPT 701
>NP_001239312
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LLSSSLAPT 9
          LLSSS  PT
Sbjct: 43 LLSSSNPPT 51
>NP_001278233
          Length = 182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LLSSSLAPT 9
          LLSSS  PT
Sbjct: 13 LLSSSNLPT 21
>NP_001263629
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLSSSLAPT 9
           LLS +L PT
Sbjct: 311 LLSKALLPT 319
>NP_612202
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLSSSLAPT 9
           LLS +L PT
Sbjct: 311 LLSKALLPT 319
>NP_008944
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSSLAPT 9
           SSS APT
Sbjct: 246 SSSFAPT 252
>NP_056121
          Length = 2620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLSSSLAPT 9
            +LSS L PT
Sbjct: 1180 VLSSKLMPT 1188
>NP_001073865
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           LLS+S +PT
Sbjct: 122 LLSASSSPT 130
>NP_777593
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SSLAPT 9
           SSLAPT
Sbjct: 182 SSLAPT 187
>NP_955452
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LSSSLAP 8
           LSSSL+P
Sbjct: 619 LSSSLSP 625
>NP_001074003
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSSLAPT 9
           SSSLAP+
Sbjct: 157 SSSLAPS 163
>XP_005276595
          Length = 207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLSSSLAPT 9
          LLS+S  PT
Sbjct: 84 LLSASTVPT 92
>XP_006722199
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSSSLAP 8
           LLS S+AP
Sbjct: 109 LLSMSMAP 116
>XP_005257785
          Length = 1887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLSSSLAP 8
            LLS S+AP
Sbjct: 1355 LLSMSMAP 1362
>XP_005254452
          Length = 2188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSSLAPT 9
           SSSLAP+
Sbjct: 157 SSSLAPS 163
>XP_005254451
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SSSLAPT 9
           SSSLAP+
Sbjct: 157 SSSLAPS 163
>XP_005253586
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSSLAPT 9
           SSSL PT
Sbjct: 695 SSSLGPT 701
>XP_005253585
          Length = 1154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSSLAPT 9
           SSSL PT
Sbjct: 728 SSSLGPT 734
>XP_006717910
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L +SSL+PT
Sbjct: 177 LRTSSLSPT 185
>XP_005269884
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L +SSL+PT
Sbjct: 177 LRTSSLSPT 185
>XP_006717909
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L +SSL+PT
Sbjct: 205 LRTSSLSPT 213
>XP_005269883
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L +SSL+PT
Sbjct: 205 LRTSSLSPT 213
>XP_006717905
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L +SSL+PT
Sbjct: 407 LRTSSLSPT 415
>XP_006717902
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L +SSL+PT
Sbjct: 444 LRTSSLSPT 452
>XP_006717901
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L +SSL+PT
Sbjct: 445 LRTSSLSPT 453
>XP_006717900
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSSSLAPT 9
           L +SSL+PT
Sbjct: 461 LRTSSLSPT 469
>XP_005250818
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSSLAPT 9
           SSS APT
Sbjct: 245 SSSFAPT 251
>XP_005250817
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSSLAPT 9
           SSS APT
Sbjct: 246 SSSFAPT 252
>XP_006713543
          Length = 2591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LSSSLAP 8
           LSSSL+P
Sbjct: 620 LSSSLSP 626
>XP_005264642
          Length = 2132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SSLAPT 9
            SSLAPT
Sbjct: 1507 SSLAPT 1512
>XP_005264641
          Length = 2133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SSLAPT 9
            SSLAPT
Sbjct: 1508 SSLAPT 1513
>XP_005270747
          Length = 2025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLSSSLAPT 9
           +LSS L PT
Sbjct: 585 VLSSKLMPT 593
>XP_006710574
          Length = 2445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLSSSLAPT 9
            +LSS L PT
Sbjct: 1005 VLSSKLMPT 1013
>XP_005270746
          Length = 2443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLSSSLAPT 9
            +LSS L PT
Sbjct: 1005 VLSSKLMPT 1013
>NP_001129475
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SSLAPT 9
           SSLAPT
Sbjct: 344 SSLAPT 349
>NP_115510
          Length = 1663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLSSSLAP 8
            LLS S+AP
Sbjct: 1189 LLSMSMAP 1196
>YP_003024032
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SSLAPT 9
           SSLAPT
Sbjct: 104 SSLAPT 109
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.114    0.276 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 528,841
Number of extensions: 1449
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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