Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_008941                                                              16    5631
NP_001278405                                                           16    5631
XP_006725362                                                           16    5631
XP_006721713                                                           16    5631
NP_004392                                                              16    7355
NP_075559                                                              16    7355
NP_998731                                                              16    7355
XP_005268213                                                           16    7355
NP_694945                                                              15    9605
NP_001136087                                                           15    9605
NP_006729                                                              15    9605
NP_001257475                                                           15    9605
NP_009131                                                              15    9605
NP_001136086                                                           15    9605
NP_005344                                                              15    9605
XP_005254913                                                           15    9605
XP_005254912                                                           15    9605
XP_005254911                                                           15    9605
XP_005254910                                                           15    9605
XP_005254909                                                           15    9605
XP_005254908                                                           15    9605
XP_005254907                                                           15    9605
XP_005254906                                                           15    9605
XP_005254905                                                           15    9605
XP_005254904                                                           15    9605
XP_005254903                                                           15    9605
XP_005254902                                                           15    9605
XP_005254901                                                           15    9605
XP_005254900                                                           15    9605
XP_005254899                                                           15    9605
XP_005254898                                                           15    9605
XP_005254897                                                           15    9605
XP_006720441                                                           15    9605
XP_006720440                                                           15    9605
XP_006720439                                                           15    9605
XP_005254896                                                           15    9605
XP_005266168                                                           15    9605
XP_005264285                                                           15    9605
XP_006712034                                                           15    9605
XP_005264284                                                           15    9605
XP_005264283                                                           15    9605
XP_005264282                                                           15    9605
XP_006711261                                                           15    9605
NP_001136088                                                           15    9605
NP_056067                                                              15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLSRQKESM 9
            LLSRQKE+M
Sbjct: 1975 LLSRQKEAM 1983
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLSRQKESM 9
            LLSRQKE+M
Sbjct: 1975 LLSRQKEAM 1983
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLSRQKESM 9
            LLSRQKE+M
Sbjct: 1928 LLSRQKEAM 1936
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLSRQKESM 9
            LLSRQKE+M
Sbjct: 2007 LLSRQKEAM 2015
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLSRQKESM 9
            LLSRQKE+M
Sbjct: 2007 LLSRQKEAM 2015
>NP_008941
          Length = 599

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           LLS+QK+ M
Sbjct: 548 LLSKQKKKM 556
>NP_001278405
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           LLS+QK+ M
Sbjct: 440 LLSKQKKKM 448
>XP_006725362
          Length = 413

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           LLS+QK+ M
Sbjct: 362 LLSKQKKKM 370
>XP_006721713
          Length = 413

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           LLS+QK+ M
Sbjct: 362 LLSKQKKKM 370
>NP_004392
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSRQKES 8
           LLS+Q+ES
Sbjct: 205 LLSKQEES 212
>NP_075559
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSRQKES 8
           LLSRQK++
Sbjct: 303 LLSRQKKA 310
>NP_998731
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSRQKES 8
           LLS+Q+ES
Sbjct: 205 LLSKQEES 212
>XP_005268213
          Length = 993

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSRQKES 8
           LLSRQ++S
Sbjct: 162 LLSRQQDS 169
>NP_694945
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSR+KE
Sbjct: 630 LLSRRKE 636
>NP_001136087
          Length = 1160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 775 LLSRQEE 781
>NP_006729
          Length = 2817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2060 ILERKKESL 2068
>NP_001257475
          Length = 1434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           +L R+KES+
Sbjct: 677 ILERKKESL 685
>NP_009131
          Length = 2813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2056 ILERKKESL 2064
>NP_001136086
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 775 LLSRQEE 781
>NP_005344
          Length = 1161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LLSRQKES 8
           ++SRQ+ES
Sbjct: 924 MISRQEES 931
>XP_005254913
          Length = 1441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           +L R+KES+
Sbjct: 677 ILERKKESL 685
>XP_005254912
          Length = 1442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           +L R+KES+
Sbjct: 678 ILERKKESL 686
>XP_005254911
          Length = 1473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           +L R+KES+
Sbjct: 709 ILERKKESL 717
>XP_005254910
          Length = 1523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           +L R+KES+
Sbjct: 759 ILERKKESL 767
>XP_005254909
          Length = 1536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           +L R+KES+
Sbjct: 772 ILERKKESL 780
>XP_005254908
          Length = 1536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLSRQKESM 9
           +L R+KES+
Sbjct: 772 ILERKKESL 780
>XP_005254907
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 1826 ILERKKESL 1834
>XP_005254906
          Length = 2675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 1911 ILERKKESL 1919
>XP_005254905
          Length = 2793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2036 ILERKKESL 2044
>XP_005254904
          Length = 2802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2038 ILERKKESL 2046
>XP_005254903
          Length = 2820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2056 ILERKKESL 2064
>XP_005254902
          Length = 2835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2078 ILERKKESL 2086
>XP_005254901
          Length = 2842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2078 ILERKKESL 2086
>XP_005254900
          Length = 2843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2079 ILERKKESL 2087
>XP_005254899
          Length = 2861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2097 ILERKKESL 2105
>XP_005254898
          Length = 2874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2117 ILERKKESL 2125
>XP_005254897
          Length = 2876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2119 ILERKKESL 2127
>XP_006720441
          Length = 2881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2117 ILERKKESL 2125
>XP_006720440
          Length = 2882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2119 ILERKKESL 2127
>XP_006720439
          Length = 2882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2118 ILERKKESL 2126
>XP_005254896
          Length = 2883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSRQKESM 9
            +L R+KES+
Sbjct: 2119 ILERKKESL 2127
>XP_005266168
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LSRQKE 7
           LSRQKE
Sbjct: 914 LSRQKE 919
>XP_005264285
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 528 LLSRQEE 534
>XP_006712034
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 810 LLSRQEE 816
>XP_005264284
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 775 LLSRQEE 781
>XP_005264283
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 810 LLSRQEE 816
>XP_005264282
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 810 LLSRQEE 816
>XP_006711261
          Length = 210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLSRQKESM 9
          LLSR+ ES+
Sbjct: 9  LLSRRPESL 17
>NP_001136088
          Length = 1160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 775 LLSRQEE 781
>NP_056067
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSRQKE 7
           LLSRQ+E
Sbjct: 810 LLSRQEE 816
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.118    0.262 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 494,595
Number of extensions: 603
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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