Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              19     665
NP_473371                                                              17    4312
NP_001002814                                                           16    5631
NP_079427                                                              16    5631
NP_056392                                                              16    5631
NP_001138997                                                           16    5631
NP_001138995                                                           16    5631
NP_001138994                                                           16    5631
NP_001138993                                                           16    5631
NP_001138992                                                           16    5631
NP_909119                                                              16    5631
NP_057537                                                              16    5631
XP_006714532                                                           16    5631
XP_005265280                                                           16    5631
XP_006713268                                                           16    5631
NP_009079                                                              16    7355
NP_065070                                                              16    7355
NP_000373                                                              16    7355
NP_001254824                                                           16    7355
NP_597712                                                              16    7355
NP_001138874                                                           16    7355
XP_005261390                                                           16    7355
XP_006724197                                                           16    7355
XP_006724196                                                           16    7355
XP_005261386                                                           16    7355
XP_006724195                                                           16    7355
XP_005261385                                                           16    7355
XP_006721636                                                           16    7355
XP_006721635                                                           16    7355
XP_006721634                                                           16    7355
NP_001026976                                                           16    7355
NP_000531                                                              15    9605
NP_001036188                                                           15    9605
NP_001092315                                                           15    9605
NP_001230925                                                           15    9605
NP_001258631                                                           15    9605
NP_001258632                                                           15    9605
NP_001035173                                                           15    9605
NP_001027                                                              15    9605
NP_071934                                                              15    9605
NP_001026884                                                           15    9605
NP_149977                                                              15    9605
XP_006724490                                                           15    9605
XP_006724489                                                           15    9605
XP_005262012                                                           15    9605
XP_006723382                                                           15    9605
XP_006723381                                                           15    9605
XP_006723380                                                           15    9605
XP_005268062                                                           15    9605
XP_005268061                                                           15    9605
XP_006718014                                                           15    9605
>NP_004251
          Length = 1208

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LLSLLQGKR 9
           LL+LLQGKR
Sbjct: 688 LLTLLQGKR 696
>NP_473371
          Length = 330

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSLLQGK 8
           LLS+L+GK
Sbjct: 159 LLSILEGK 166
>NP_001002814
          Length = 1283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSLLQGKR 9
           LLSL+ GK+
Sbjct: 436 LLSLMTGKK 444
>NP_079427
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLSLLQGKR 9
           LLSL+ GK+
Sbjct: 436 LLSLMTGKK 444
>NP_056392
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           LLSLLQ K
Sbjct: 348 LLSLLQAK 355
>NP_001138997
          Length = 983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           LLSLLQ K
Sbjct: 351 LLSLLQAK 358
>NP_001138995
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           LLSLLQ K
Sbjct: 340 LLSLLQAK 347
>NP_001138994
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           LLSLLQ K
Sbjct: 319 LLSLLQAK 326
>NP_001138993
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           LLSLLQ K
Sbjct: 348 LLSLLQAK 355
>NP_001138992
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           LLSLLQ K
Sbjct: 348 LLSLLQAK 355
>NP_909119
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSLLQGK 8
           LLSL++GK
Sbjct: 350 LLSLVEGK 357
>NP_057537
          Length = 722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSLLQGK 8
           LLSL++GK
Sbjct: 357 LLSLVEGK 364
>XP_006714532
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           LLSLLQ K
Sbjct: 348 LLSLLQAK 355
>XP_005265280
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSLLQGK 8
           LLSL++GK
Sbjct: 279 LLSLVEGK 286
>XP_006713268
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSLLQGK 8
           LLSL++GK
Sbjct: 357 LLSLVEGK 364
>NP_009079
          Length = 631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLQGKR 9
           LLQGKR
Sbjct: 348 LLQGKR 353
>NP_065070
          Length = 1429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLLQGKR 9
          SLLQGK+
Sbjct: 16 SLLQGKQ 22
>NP_000373
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLSLLQGKR 9
           +LSLL+G++
Sbjct: 291 ILSLLEGQK 299
>NP_001254824
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLLQGKR 9
           SLL+GKR
Sbjct: 416 SLLRGKR 422
>NP_597712
          Length = 443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLLQGKR 9
           SLL+GKR
Sbjct: 418 SLLRGKR 424
>NP_001138874
          Length = 922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LSLLQGK 8
           LSLL+GK
Sbjct: 745 LSLLEGK 751
>XP_005261390
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLLQGKR 9
           SLL+GKR
Sbjct: 301 SLLRGKR 307
>XP_006724197
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLLQGKR 9
           SLL+GKR
Sbjct: 304 SLLRGKR 310
>XP_006724196
          Length = 361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLLQGKR 9
           SLL+GKR
Sbjct: 336 SLLRGKR 342
>XP_005261386
          Length = 417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLLQGKR 9
           SLL+GKR
Sbjct: 392 SLLRGKR 398
>XP_006724195
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLLQGKR 9
           SLL+GKR
Sbjct: 399 SLLRGKR 405
>XP_005261385
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLLQGKR 9
           SLL+GKR
Sbjct: 420 SLLRGKR 426
>XP_006721636
          Length = 615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLQGKR 9
           LLQGKR
Sbjct: 332 LLQGKR 337
>XP_006721635
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLQGKR 9
           LLQGKR
Sbjct: 355 LLQGKR 360
>XP_006721634
          Length = 639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLQGKR 9
           LLQGKR
Sbjct: 356 LLQGKR 361
>NP_001026976
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLSLLQGKR 9
           +LSLL+G++
Sbjct: 291 ILSLLEGQK 299
>NP_000531
          Length = 5038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLSLLQG 7
            LLSLL+G
Sbjct: 4026 LLSLLEG 4032
>NP_001036188
          Length = 5033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLSLLQG 7
            LLSLL+G
Sbjct: 4021 LLSLLEG 4027
>NP_001092315
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLSLLQGKR 9
           L+ LLQG R
Sbjct: 159 LVCLLQGSR 167
>NP_001230925
          Length = 4865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLSLLQG 7
            LLSLL+G
Sbjct: 3873 LLSLLEG 3879
>NP_001258631
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLSLLQGKR 9
           L+ LLQG R
Sbjct: 197 LVCLLQGSR 205
>NP_001258632
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLSLLQGKR 9
           L+ LLQG R
Sbjct: 97  LVCLLQGSR 105
>NP_001035173
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLSLLQGKR 9
           L+ LLQG R
Sbjct: 159 LVCLLQGSR 167
>NP_001027
          Length = 4870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLSLLQG 7
            LLSLL+G
Sbjct: 3878 LLSLLEG 3884
>NP_071934
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSLLQG 7
           LLS+LQG
Sbjct: 291 LLSVLQG 297
>NP_001026884
          Length = 1240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSLLQG 7
           LLS+LQG
Sbjct: 291 LLSVLQG 297
>NP_149977
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           +L LLQGK
Sbjct: 526 VLRLLQGK 533
>XP_006724490
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           +L LLQGK
Sbjct: 471 VLRLLQGK 478
>XP_006724489
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           +L LLQGK
Sbjct: 471 VLRLLQGK 478
>XP_005262012
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLSLLQGK 8
           +L LLQGK
Sbjct: 501 VLRLLQGK 508
>XP_006723382
          Length = 5027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLSLLQG 7
            LLSLL+G
Sbjct: 4015 LLSLLEG 4021
>XP_006723381
          Length = 5031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLSLLQG 7
            LLSLL+G
Sbjct: 4019 LLSLLEG 4025
>XP_006723380
          Length = 5032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLSLLQG 7
            LLSLL+G
Sbjct: 4020 LLSLLEG 4026
>XP_005268062
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSLLQG 7
           LLS+LQG
Sbjct: 323 LLSVLQG 329
>XP_005268061
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLSLLQG 7
           LLS+LQG
Sbjct: 323 LLSVLQG 329
>XP_006718014
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLSLLQGKR 9
           L+ LLQG R
Sbjct: 183 LVCLLQGSR 191
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.146    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 489,398
Number of extensions: 738
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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