Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              17    3301
NP_005913                                                              17    3301
XP_005267046                                                           17    3301
XP_005267045                                                           17    3301
NP_001238892                                                           16    7355
NP_055722                                                              16    7355
NP_001238891                                                           16    7355
NP_056410                                                              16    7355
XP_006725061                                                           16    7355
XP_005252857                                                           15    9605
XP_006718211                                                           15    9605
>NP_006715
          Length = 1558

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLSIKLLVR 9
           LLSIK LVR
Sbjct: 645 LLSIKQLVR 653
>NP_005913
          Length = 1608

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLSIKLLVR 9
           LLSIK LVR
Sbjct: 645 LLSIKQLVR 653
>XP_005267046
          Length = 1554

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLSIKLLVR 9
           LLSIK LVR
Sbjct: 645 LLSIKQLVR 653
>XP_005267045
          Length = 1604

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLSIKLLVR 9
           LLSIK LVR
Sbjct: 645 LLSIKQLVR 653
>NP_001238892
          Length = 791

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLSIKLLVR 9
           LLS+++L+R
Sbjct: 455 LLSLEILIR 463
>NP_055722
          Length = 1578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSIKLLVR 9
            LS+KLL R
Sbjct: 1549 LSVKLLAR 1556
>NP_001238891
          Length = 871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLSIKLLVR 9
           LLS+++L+R
Sbjct: 455 LLSLEILIR 463
>NP_056410
          Length = 871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLSIKLLVR 9
           LLS+++L+R
Sbjct: 455 LLSLEILIR 463
>XP_006725061
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLSIKLLVR 9
           LLS+++L+R
Sbjct: 455 LLSLEILIR 463
>XP_005252857
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LLSIKLLV 8
          LLS+KLL+
Sbjct: 70 LLSLKLLL 77
>XP_006718211
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LLSIKLLV 8
          LLS+KLL+
Sbjct: 70 LLSLKLLL 77
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.160    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 286,196
Number of extensions: 238
Number of successful extensions: 11
Number of sequences better than 10000.0: 11
Number of HSP's gapped: 11
Number of HSP's successfully gapped: 11
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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