Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              18    1135
XP_005273257                                                           18    1135
NP_001073998                                                           18    1935
XP_005249879                                                           18    1935
NP_001157862                                                           17    4312
NP_055062                                                              17    4312
NP_001157861                                                           17    4312
NP_001157860                                                           17    4312
NP_001157859                                                           17    4312
NP_001157858                                                           17    4312
NP_057424                                                              17    4312
XP_006714485                                                           17    4312
XP_005263418                                                           17    4312
XP_005263417                                                           17    4312
XP_006714484                                                           17    4312
XP_005263416                                                           17    4312
XP_006714483                                                           17    4312
XP_005263415                                                           17    4312
NP_001273758                                                           16    5631
NP_660202                                                              16    5631
NP_001160158                                                           16    5631
NP_000280                                                              16    5631
NP_001160160                                                           16    5631
XP_006719527                                                           16    5631
XP_006719526                                                           16    5631
XP_005269037                                                           16    5631
XP_005269036                                                           16    5631
XP_005269035                                                           16    5631
XP_005269034                                                           16    5631
XP_005269033                                                           16    5631
XP_005269032                                                           16    5631
XP_005269031                                                           16    5631
NP_001160159                                                           16    5631
NP_036565                                                              16    7355
NP_001005526                                                           16    7355
NP_000245                                                              15    9605
NP_001258463                                                           15    9605
NP_001380                                                              15    9605
NP_075047                                                              15    9605
XP_006724038                                                           15    9605
XP_006723924                                                           15    9605
XP_006723923                                                           15    9605
XP_006723922                                                           15    9605
XP_005260572                                                           15    9605
XP_005273202                                                           15    9605
XP_006711833                                                           15    9605
XP_005273200                                                           15    9605
XP_005273198                                                           15    9605
>NP_064450
          Length = 1722

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSDIQQA
Sbjct: 195 LLSDIQQA 202
>XP_005273257
          Length = 1726

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSDIQQA
Sbjct: 195 LLSDIQQA 202
>NP_001073998
          Length = 483

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LLSDIQQAT 9
          LL+DIQQ T
Sbjct: 49 LLADIQQGT 57
>XP_005249879
          Length = 483

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LLSDIQQAT 9
          LL+DIQQ T
Sbjct: 49 LLADIQQGT 57
>NP_001157862
          Length = 827

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 204 LSDIYQAT 211
>NP_055062
          Length = 1499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  LSDIQQAT 9
          LSDI QAT
Sbjct: 59 LSDIYQAT 66
>NP_001157861
          Length = 1391

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 204 LSDIYQAT 211
>NP_001157860
          Length = 1504

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 204 LSDIYQAT 211
>NP_001157859
          Length = 1509

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 204 LSDIYQAT 211
>NP_001157858
          Length = 1609

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 204 LSDIYQAT 211
>NP_057424
          Length = 1601

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 204 LSDIYQAT 211
>XP_006714485
          Length = 1585

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 104 LSDIYQAT 111
>XP_005263418
          Length = 1654

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 214 LSDIYQAT 221
>XP_005263417
          Length = 1660

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 220 LSDIYQAT 227
>XP_006714484
          Length = 1685

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 220 LSDIYQAT 227
>XP_005263416
          Length = 1693

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 220 LSDIYQAT 227
>XP_006714483
          Length = 1695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 214 LSDIYQAT 221
>XP_005263415
          Length = 1701

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSDIQQAT 9
           LSDI QAT
Sbjct: 220 LSDIYQAT 227
>NP_001273758
          Length = 525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLSDIQQAT 9
          LL+D+ QAT
Sbjct: 16 LLTDLYQAT 24
>NP_660202
          Length = 538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLSDIQQAT 9
          LL+D+ QAT
Sbjct: 16 LLTDLYQAT 24
>NP_001160158
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 206 LLSDLQKA 213
>NP_000280
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 135 LLSDLQKA 142
>NP_001160160
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 135 LLSDLQKA 142
>XP_006719527
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 135 LLSDLQKA 142
>XP_006719526
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 135 LLSDLQKA 142
>XP_005269037
          Length = 811

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 166 LLSDLQKA 173
>XP_005269036
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 206 LLSDLQKA 213
>XP_005269035
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 206 LLSDLQKA 213
>XP_005269034
          Length = 851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 206 LLSDLQKA 213
>XP_005269033
          Length = 883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 238 LLSDLQKA 245
>XP_005269032
          Length = 883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 238 LLSDLQKA 245
>XP_005269031
          Length = 883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 238 LLSDLQKA 245
>NP_001160159
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLSDIQQA 8
           LLSD+Q+A
Sbjct: 135 LLSDLQKA 142
>NP_036565
          Length = 1304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLSDIQQAT 9
          LL+DI Q+T
Sbjct: 90 LLNDIPQST 98
>NP_001005526
          Length = 144

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLSDIQQAT 9
          LL+DI Q+T
Sbjct: 90 LLNDIPQST 98
>NP_000245
          Length = 1265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LSDIQQAT 9
            L+DI+Q+T
Sbjct: 1192 LADIEQST 1199
>NP_001258463
          Length = 1994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSDIQQAT 9
            +L D+Q+AT
Sbjct: 1534 ILYDLQEAT 1542
>NP_001380
          Length = 2012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSDIQQAT 9
            +L D+Q+AT
Sbjct: 1534 ILYDLQEAT 1542
>NP_075047
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LSDIQQ 7
           LSDIQQ
Sbjct: 746 LSDIQQ 751
>XP_006724038
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLSDIQQAT 9
            +L D+Q+AT
Sbjct: 1429 ILYDLQEAT 1437
>XP_006723924
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LSDIQQ 7
           LSDIQQ
Sbjct: 747 LSDIQQ 752
>XP_006723923
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LSDIQQ 7
           LSDIQQ
Sbjct: 747 LSDIQQ 752
>XP_006723922
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LSDIQQ 7
           LSDIQQ
Sbjct: 747 LSDIQQ 752
>XP_005260572
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LSDIQQ 7
           LSDIQQ
Sbjct: 747 LSDIQQ 752
>XP_005273202
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSDIQQAT 9
           L+DI+Q+T
Sbjct: 646 LADIEQST 653
>XP_006711833
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSDIQQAT 9
           L+DI+Q+T
Sbjct: 880 LADIEQST 887
>XP_005273200
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LSDIQQAT 9
            L+DI+Q+T
Sbjct: 1141 LADIEQST 1148
>XP_005273198
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LSDIQQAT 9
            L+DI+Q+T
Sbjct: 1191 LADIEQST 1198
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.124    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 366,384
Number of extensions: 472
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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