Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005912                                                              20     509
XP_005248577                                                           20     509
XP_005248576                                                           20     509
NP_001157281                                                           17    3301
XP_006725317                                                           17    3301
XP_005256511                                                           17    3301
NP_054742                                                              17    4312
NP_065135                                                              17    4312
NP_597705                                                              16    5631
NP_001171655                                                           16    5631
NP_000346                                                              16    5631
NP_071908                                                              16    5631
NP_001192248                                                           16    5631
XP_005256815                                                           16    5631
XP_005256814                                                           16    5631
XP_005256813                                                           16    5631
NP_001077430                                                           16    7355
NP_775907                                                              16    7355
NP_003844                                                              16    7355
NP_001171481                                                           16    7355
NP_055325                                                              16    7355
NP_149015                                                              16    7355
NP_689472                                                              16    7355
NP_003495                                                              16    7355
XP_005261342                                                           16    7355
XP_005261343                                                           16    7355
XP_005258866                                                           16    7355
XP_006715989                                                           16    7355
XP_005264091                                                           16    7355
NP_001025053                                                           15    9605
NP_057726                                                              15    9605
NP_006501                                                              15    9605
NP_620133                                                              15    9605
NP_006729                                                              15    9605
NP_060603                                                              15    9605
NP_009131                                                              15    9605
NP_001138889                                                           15    9605
NP_795352                                                              15    9605
NP_954974                                                              15    9605
NP_085059                                                              15    9605
XP_005254495                                                           15    9605
XP_005254907                                                           15    9605
XP_005254906                                                           15    9605
XP_005254905                                                           15    9605
XP_005254904                                                           15    9605
XP_005254903                                                           15    9605
XP_005254902                                                           15    9605
XP_005254901                                                           15    9605
XP_005254900                                                           15    9605
XP_005254899                                                           15    9605
XP_005254898                                                           15    9605
XP_005254897                                                           15    9605
XP_006720441                                                           15    9605
XP_006720440                                                           15    9605
XP_006720439                                                           15    9605
XP_005254896                                                           15    9605
XP_005266187                                                           15    9605
XP_005266186                                                           15    9605
XP_005266185                                                           15    9605
XP_005266183                                                           15    9605
XP_005266182                                                           15    9605
XP_005266181                                                           15    9605
XP_005266180                                                           15    9605
XP_006713747                                                           15    9605
XP_005247629                                                           15    9605
XP_005247628                                                           15    9605
XP_006712017                                                           15    9605
XP_005245910                                                           15    9605
XP_005245909                                                           15    9605
XP_005245908                                                           15    9605
XP_005245907                                                           15    9605
XP_005245906                                                           15    9605
XP_005245905                                                           15    9605
XP_006710340                                                           15    9605
XP_005270398                                                           15    9605
XP_006710339                                                           15    9605
XP_006710338                                                           15    9605
>NP_005912
          Length = 1512

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           LLQPV DTI
Sbjct: 679 LLQPVVDTI 687
>XP_005248577
          Length = 1349

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           LLQPV DTI
Sbjct: 516 LLQPVVDTI 524
>XP_005248576
          Length = 1375

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           LLQPV DTI
Sbjct: 542 LLQPVVDTI 550
>NP_001157281
          Length = 1941

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQPV DT+
Sbjct: 818 LQPVLDTL 825
>XP_006725317
          Length = 1745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQPV DT+
Sbjct: 818 LQPVLDTL 825
>XP_005256511
          Length = 1746

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQPV DT+
Sbjct: 818 LQPVLDTL 825
>NP_054742
          Length = 494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QPVADT
Sbjct: 236 QPVADT 241
>NP_065135
          Length = 450

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LQPVADT 8
          L+PVADT
Sbjct: 45 LRPVADT 51
>NP_597705
          Length = 1099

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           +L P++DTI
Sbjct: 642 ILSPLSDTI 650
>NP_001171655
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           +L+P A+TI
Sbjct: 288 MLEPAAETI 296
>NP_000346
          Length = 427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           +L+P A+TI
Sbjct: 315 MLEPAAETI 323
>NP_071908
          Length = 435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           L+QP+A+ I
Sbjct: 347 LIQPIAEKI 355
>NP_001192248
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           L+QP+A+ I
Sbjct: 239 LIQPIAEKI 247
>XP_005256815
          Length = 322

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           L+QP+A+ I
Sbjct: 234 LIQPIAEKI 242
>XP_005256814
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           L+QP+A+ I
Sbjct: 239 LIQPIAEKI 247
>XP_005256813
          Length = 375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLQPVADTI 9
           L+QP+A+ I
Sbjct: 287 LIQPIAEKI 295
>NP_001077430
          Length = 1523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    LLQPVADT 8
            LLQP  DT
Sbjct: 1308 LLQPPVDT 1315
>NP_775907
          Length = 1518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    LLQPVADT 8
            LLQP  DT
Sbjct: 1303 LLQPPVDT 1310
>NP_003844
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLQPVADTI 9
           +L PV DT+
Sbjct: 253 ILDPVEDTL 261
>NP_001171481
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLQPVADTI 9
          +LQP  DTI
Sbjct: 86 ILQPDEDTI 94
>NP_055325
          Length = 4935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    PVADTI 9
            PVADT+
Sbjct: 2284 PVADTV 2289
>NP_149015
          Length = 5142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    PVADTI 9
            PVADT+
Sbjct: 2284 PVADTV 2289
>NP_689472
          Length = 1910

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QPVADTI 9
           QPV DT+
Sbjct: 900 QPVKDTV 906
>NP_003495
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLQPVADTI 9
          +LQP  DTI
Sbjct: 86 ILQPDEDTI 94
>XP_005261342
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLQPVADTI 9
          +LQP  DTI
Sbjct: 86 ILQPDEDTI 94
>XP_005261343
          Length = 567

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLQPVADTI 9
          +LQP  DTI
Sbjct: 86 ILQPDEDTI 94
>XP_005258866
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    LLQPVADT 8
            LLQP  DT
Sbjct: 1271 LLQPPVDT 1278
>XP_006715989
          Length = 5148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    PVADTI 9
            PVADT+
Sbjct: 2284 PVADTV 2289
>XP_005264091
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLQPVADTI 9
           +L PV DT+
Sbjct: 111 ILDPVEDTL 119
>NP_001025053
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQP+AD +
Sbjct: 300 LQPLADPL 307
>NP_057726
          Length = 3674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           +QP ADT+
Sbjct: 922 VQPQADTL 929
>NP_006501
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLQPVADTI 9
           LLQ + DT+
Sbjct: 247 LLQDIGDTL 255
>NP_620133
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QP+ADT
Sbjct: 274 QPLADT 279
>NP_006729
          Length = 2817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>NP_060603
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQPVADTI 9
           L PV DT+
Sbjct: 235 LPPVCDTV 242
>NP_009131
          Length = 2813

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>NP_001138889
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQPVADTI 9
           L PV DT+
Sbjct: 161 LPPVCDTV 168
>NP_795352
          Length = 1801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLQPVADT 8
            +LQ VADT
Sbjct: 1755 ILQVVADT 1762
>NP_954974
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLQPVADT 8
           LLQ +ADT
Sbjct: 577 LLQKMADT 584
>NP_085059
          Length = 1516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  LQPVADT 8
          +QP ADT
Sbjct: 54 VQPTADT 60
>XP_005254495
          Length = 3694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           +QP ADT+
Sbjct: 942 VQPQADTL 949
>XP_005254907
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LLQPVA 6
           LLQPVA
Sbjct: 894 LLQPVA 899
>XP_005254906
          Length = 2675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LLQPVA 6
           LLQPVA
Sbjct: 979 LLQPVA 984
>XP_005254905
          Length = 2793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254904
          Length = 2802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254903
          Length = 2820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254902
          Length = 2835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254901
          Length = 2842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254900
          Length = 2843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254899
          Length = 2861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254898
          Length = 2874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254897
          Length = 2876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_006720441
          Length = 2881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_006720440
          Length = 2882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_006720439
          Length = 2882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005254896
          Length = 2883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLQPVA 6
            LLQPVA
Sbjct: 1187 LLQPVA 1192
>XP_005266187
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QP+ADT
Sbjct: 98  QPLADT 103
>XP_005266186
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QP+ADT
Sbjct: 98  QPLADT 103
>XP_005266185
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QP+ADT
Sbjct: 98  QPLADT 103
>XP_005266183
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QP+ADT
Sbjct: 98  QPLADT 103
>XP_005266182
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QP+ADT
Sbjct: 98  QPLADT 103
>XP_005266181
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QP+ADT
Sbjct: 98  QPLADT 103
>XP_005266180
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QPVADT 8
           QP+ADT
Sbjct: 98  QPLADT 103
>XP_006713747
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQPVADTI 9
           L PV DT+
Sbjct: 161 LPPVCDTV 168
>XP_005247629
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQPVADTI 9
           L PV DT+
Sbjct: 161 LPPVCDTV 168
>XP_005247628
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LQPVADTI 9
           L PV DT+
Sbjct: 161 LPPVCDTV 168
>XP_006712017
          Length = 1028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLQPVADT 8
           LLQ +ADT
Sbjct: 586 LLQKMADT 593
>XP_005245910
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQP+AD +
Sbjct: 300 LQPLADPL 307
>XP_005245909
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQP+AD +
Sbjct: 300 LQPLADPL 307
>XP_005245908
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQP+AD +
Sbjct: 300 LQPLADPL 307
>XP_005245907
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQP+AD +
Sbjct: 300 LQPLADPL 307
>XP_005245906
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQP+AD +
Sbjct: 300 LQPLADPL 307
>XP_005245905
          Length = 1603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQPVADTI 9
           LQP+AD +
Sbjct: 300 LQPLADPL 307
>XP_006710340
          Length = 1815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLQPVADT 8
            +LQ VADT
Sbjct: 1769 ILQVVADT 1776
>XP_005270398
          Length = 1882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLQPVADT 8
            +LQ VADT
Sbjct: 1755 ILQVVADT 1762
>XP_006710339
          Length = 1896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLQPVADT 8
            +LQ VADT
Sbjct: 1769 ILQVVADT 1776
>XP_006710338
          Length = 1896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLQPVADT 8
            +LQ VADT
Sbjct: 1769 ILQVVADT 1776
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.141    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 663,570
Number of extensions: 1065
Number of successful extensions: 77
Number of sequences better than 10000.0: 77
Number of HSP's gapped: 77
Number of HSP's successfully gapped: 77
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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