Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1935
NP_001035957                                                           18    1935
XP_006721991                                                           18    1935
XP_006721990                                                           18    1935
XP_006721989                                                           18    1935
XP_005258041                                                           18    1935
XP_006721988                                                           18    1935
XP_006721987                                                           18    1935
XP_006721986                                                           18    1935
XP_005258040                                                           18    1935
XP_006721985                                                           18    1935
NP_005453                                                              16    7355
NP_055950                                                              16    7355
XP_005250292                                                           16    7355
XP_003846820                                                           16    7355
>NP_000258
          Length = 2818

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1304 LLRIVITSS 1312
>NP_001035957
          Length = 2839

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1304 LLRIVITSS 1312
>XP_006721991
          Length = 1632

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1314 LLRIVITSS 1322
>XP_006721990
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1314 LLRIVITSS 1322
>XP_006721989
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1314 LLRIVITSS 1322
>XP_005258041
          Length = 2836

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1304 LLRIVITSS 1312
>XP_006721988
          Length = 2846

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1314 LLRIVITSS 1322
>XP_006721987
          Length = 2849

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1314 LLRIVITSS 1322
>XP_006721986
          Length = 2854

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1301 LLRIVITSS 1309
>XP_005258040
          Length = 2857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1304 LLRIVITSS 1312
>XP_006721985
          Length = 2867

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLQIVITSS 9
            LL+IVITSS
Sbjct: 1314 LLRIVITSS 1322
>NP_005453
          Length = 1142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQIVITSS 9
           LLQI +TSS
Sbjct: 337 LLQIPMTSS 345
>NP_055950
          Length = 2012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLQIVITSS 9
            L Q+++TSS
Sbjct: 1626 LCQVILTSS 1634
>XP_005250292
          Length = 1654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLQIVITSS 9
            L Q+++TSS
Sbjct: 1268 LCQVILTSS 1276
>XP_003846820
          Length = 1177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQIVITSS 9
           LLQI +TSS
Sbjct: 372 LLQIPMTSS 380
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.135    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 293,093
Number of extensions: 261
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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