Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     509
NP_859049                                                              17    2528
NP_001269781                                                           17    2528
NP_659449                                                              17    2528
NP_057043                                                              17    2528
NP_001269782                                                           17    2528
NP_001269783                                                           17    2528
NP_001135772                                                           17    2528
NP_001137484                                                           17    2528
XP_005252445                                                           17    2528
XP_006717455                                                           17    2528
XP_005246400                                                           17    2528
NP_689736                                                              17    2528
NP_001075019                                                           17    3301
XP_006724836                                                           17    3301
XP_005262507                                                           17    3301
XP_006724835                                                           17    3301
XP_006724834                                                           17    3301
XP_006724833                                                           17    3301
XP_006724832                                                           17    3301
XP_006724831                                                           17    3301
XP_006724830                                                           17    3301
XP_005262504                                                           17    3301
NP_001099133                                                           17    4312
NP_001230589                                                           17    4312
NP_001230590                                                           17    4312
NP_001032                                                              16    5631
NP_001268885                                                           16    5631
NP_653314                                                              16    7355
NP_001714                                                              16    7355
NP_005236                                                              16    7355
NP_036467                                                              16    7355
NP_444504                                                              16    7355
NP_060382                                                              16    7355
NP_036229                                                              16    7355
NP_001158608                                                           16    7355
XP_005272534                                                           16    7355
XP_005272533                                                           16    7355
XP_005272532                                                           16    7355
XP_005249383                                                           16    7355
XP_005263140                                                           16    7355
XP_006714202                                                           16    7355
XP_005262892                                                           16    7355
XP_005262891                                                           16    7355
XP_006712935                                                           16    7355
XP_006712934                                                           16    7355
XP_006712933                                                           16    7355
XP_006712016                                                           16    7355
XP_006710372                                                           16    7355
XP_005270458                                                           16    7355
XP_005270457                                                           16    7355
NP_852118                                                              16    7355
NP_060034                                                              15    9605
NP_003744                                                              15    9605
XP_006719539                                                           15    9605
XP_005252650                                                           15    9605
XP_006717569                                                           15    9605
XP_006717568                                                           15    9605
XP_006717567                                                           15    9605
>NP_004295
          Length = 1620

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LLQFNLNEL 9
           LLQFNL+EL
Sbjct: 165 LLQFNLSEL 173
>NP_859049
          Length = 287

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 205 LLQFNIN 211
>NP_001269781
          Length = 316

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 234 LLQFNIN 240
>NP_659449
          Length = 341

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 259 LLQFNIN 265
>NP_057043
          Length = 296

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QFNLNEL 9
           +FNLNEL
Sbjct: 254 EFNLNEL 260
>NP_001269782
          Length = 287

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 205 LLQFNIN 211
>NP_001269783
          Length = 208

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 126 LLQFNIN 132
>NP_001135772
          Length = 308

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 228 LLQFNIN 234
>NP_001137484
          Length = 258

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   QFNLNEL 9
           +FNLNEL
Sbjct: 216 EFNLNEL 222
>XP_005252445
          Length = 294

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 212 LLQFNIN 218
>XP_006717455
          Length = 317

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 235 LLQFNIN 241
>XP_005246400
          Length = 359

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 279 LLQFNIN 285
>NP_689736
          Length = 289

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLQFNLN 7
           LLQFN+N
Sbjct: 209 LLQFNIN 215
>NP_001075019
          Length = 1593

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_006724836
          Length = 1582

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_005262507
          Length = 1594

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_006724835
          Length = 1615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_006724834
          Length = 1615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_006724833
          Length = 1620

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_006724832
          Length = 1640

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_006724831
          Length = 1640

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_006724830
          Length = 1642

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>XP_005262504
          Length = 1642

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLQFNLNEL 9
           LLQFNL +L
Sbjct: 273 LLQFNLIDL 281
>NP_001099133
          Length = 238

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQFNLNEL 9
           +QFNLN++
Sbjct: 212 VQFNLNDV 219
>NP_001230589
          Length = 223

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQFNLNEL 9
           +QFNLN++
Sbjct: 197 VQFNLNDV 204
>NP_001230590
          Length = 185

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQFNLNEL 9
           +QFNLN++
Sbjct: 159 VQFNLNDV 166
>NP_001032
          Length = 1827

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQFNLNE 8
            +QFNLN+
Sbjct: 1743 VQFNLNQ 1749
>NP_001268885
          Length = 3631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QFNLNEL 9
            QFNLN++
Sbjct: 2812 QFNLNDV 2818
>NP_653314
          Length = 573

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FNLNEL 9
           FNLNE+
Sbjct: 154 FNLNEI 159
>NP_001714
          Length = 2649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    LQFNLNE 8
            L FN+NE
Sbjct: 2399 LHFNINE 2405
>NP_005236
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QFNLNEL 9
            QF++NEL
Sbjct: 3171 QFSINEL 3177
>NP_036467
          Length = 1098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LQFNLNEL 9
            L FN+NE+
Sbjct: 1060 LSFNVNEV 1067
>NP_444504
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLQFNLNEL 9
           LLQFN+  +
Sbjct: 312 LLQFNMGHI 320
>NP_060382
          Length = 1022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FNLNEL 9
           FN+NEL
Sbjct: 584 FNINEL 589
>NP_036229
          Length = 179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LLQFNLNEL 9
          L QF++NE+
Sbjct: 33 LYQFSMNEV 41
>NP_001158608
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FNLNEL 9
           FN+NEL
Sbjct: 584 FNINEL 589
>XP_005272534
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LQFNLNEL 9
            L FN+NE+
Sbjct: 1033 LSFNVNEV 1040
>XP_005272533
          Length = 1096

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LQFNLNEL 9
            L FN+NE+
Sbjct: 1058 LSFNVNEV 1065
>XP_005272532
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LQFNLNEL 9
            L FN+NE+
Sbjct: 1062 LSFNVNEV 1069
>XP_005249383
          Length = 3186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    LQFNLNE 8
            L FN+NE
Sbjct: 2936 LHFNINE 2942
>XP_005263140
          Length = 1034

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FNLNEL 9
           FN+NEL
Sbjct: 596 FNINEL 601
>XP_006714202
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QFNLNEL 9
            QF++NEL
Sbjct: 3171 QFSINEL 3177
>XP_005262892
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QFNLNEL 9
            QF++NEL
Sbjct: 3171 QFSINEL 3177
>XP_005262891
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QFNLNEL 9
            QF++NEL
Sbjct: 3171 QFSINEL 3177
>XP_006712935
          Length = 977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQFNLNEL 9
           L+F +NEL
Sbjct: 386 LEFKINEL 393
>XP_006712934
          Length = 1583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQFNLNEL 9
           L+F +NEL
Sbjct: 282 LEFKINEL 289
>XP_006712933
          Length = 1687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQFNLNEL 9
           L+F +NEL
Sbjct: 386 LEFKINEL 393
>XP_006712016
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FNLNEL 9
           FNLNE+
Sbjct: 154 FNLNEI 159
>XP_006710372
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLQFNLNEL 9
           LLQFN+  +
Sbjct: 145 LLQFNMGHI 153
>XP_005270458
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLQFNLNEL 9
           LLQFN+  +
Sbjct: 270 LLQFNMGHI 278
>XP_005270457
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLQFNLNEL 9
           LLQFN+  +
Sbjct: 312 LLQFNMGHI 320
>NP_852118
          Length = 1684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LQFNLNEL 9
           L+F +NEL
Sbjct: 383 LEFKINEL 390
>NP_060034
          Length = 2551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FNLNEL 9
           FN+NEL
Sbjct: 418 FNVNEL 423
>NP_003744
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLQFNLNEL 9
           +LQFNL  L
Sbjct: 114 MLQFNLQIL 122
>XP_006719539
          Length = 2246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FNLNEL 9
           FN+NEL
Sbjct: 418 FNVNEL 423
>XP_005252650
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LLQFNLNEL 9
           ++QF+LN++
Sbjct: 302 IIQFDLNKV 310
>XP_006717569
          Length = 1278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LLQFNLNEL 9
           ++QF+LN++
Sbjct: 888 IIQFDLNKV 896
>XP_006717568
          Length = 1314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LLQFNLNEL 9
           ++QF+LN++
Sbjct: 924 IIQFDLNKV 932
>XP_006717567
          Length = 1385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    LLQFNLNEL 9
            ++QF+LN++
Sbjct: 995  IIQFDLNKV 1003
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.148    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,141
Number of extensions: 757
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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