Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           19     665
NP_000242                                                              19     665
XP_005264389                                                           19     665
NP_000631                                                              17    3301
NP_060595                                                              17    4312
NP_001011722                                                           17    4312
NP_060271                                                              17    4312
XP_006710797                                                           17    4312
XP_005245986                                                           17    4312
XP_005245985                                                           17    4312
XP_005245984                                                           17    4312
XP_005245983                                                           17    4312
XP_006710796                                                           17    4312
XP_006710795                                                           17    4312
XP_005245982                                                           17    4312
XP_005245981                                                           17    4312
XP_006710794                                                           17    4312
XP_006710793                                                           17    4312
XP_006710792                                                           17    4312
XP_006710791                                                           17    4312
XP_006710790                                                           17    4312
XP_005245980                                                           17    4312
NP_997465                                                              16    5631
XP_006723231                                                           16    5631
XP_005258877                                                           16    5631
XP_005258876                                                           16    5631
NP_054756                                                              16    5631
NP_112191                                                              16    7355
NP_001074924                                                           16    7355
NP_066580                                                              16    7355
NP_060474                                                              16    7355
XP_005253535                                                           16    7355
XP_005253534                                                           16    7355
XP_005253531                                                           16    7355
XP_005270251                                                           16    7355
XP_005270250                                                           16    7355
XP_006713895                                                           16    7355
XP_005247980                                                           16    7355
XP_005247979                                                           16    7355
XP_005247978                                                           16    7355
XP_005247626                                                           16    7355
XP_005247625                                                           16    7355
NP_602307                                                              16    7355
NP_055694                                                              16    7355
NP_001165882                                                           15    9605
NP_001165883                                                           15    9605
NP_620409                                                              15    9605
NP_060341                                                              15    9605
NP_001243391                                                           15    9605
NP_001243389                                                           15    9605
NP_001243392                                                           15    9605
NP_001243385                                                           15    9605
XP_006710999                                                           15    9605
XP_006710998                                                           15    9605
XP_005244820                                                           15    9605
XP_006710778                                                           15    9605
NP_001005323                                                           15    9605
>NP_001245210
          Length = 868

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLLVVFVTP 9
           LLL VFVTP
Sbjct: 365 LLLAVFVTP 373
>NP_000242
          Length = 934

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLLVVFVTP 9
           LLL VFVTP
Sbjct: 431 LLLAVFVTP 439
>XP_005264389
          Length = 921

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLLVVFVTP 9
           LLL VFVTP
Sbjct: 431 LLLAVFVTP 439
>NP_000631
          Length = 380

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLLVVFVT 8
           L+LV+FVT
Sbjct: 352 LILVIFVT 359
>NP_060595
          Length = 1279

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 732 MVVFITP 738
>NP_001011722
          Length = 1240

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 693 MVVFITP 699
>NP_060271
          Length = 183

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LLLVVFVTP 9
          L+L+V+ TP
Sbjct: 84 LILIVYCTP 92
>XP_006710797
          Length = 1040

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 493 MVVFITP 499
>XP_005245986
          Length = 1052

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 505 MVVFITP 511
>XP_005245985
          Length = 1054

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 507 MVVFITP 513
>XP_005245984
          Length = 1057

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 510 MVVFITP 516
>XP_005245983
          Length = 1235

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 688 MVVFITP 694
>XP_006710796
          Length = 1236

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 689 MVVFITP 695
>XP_006710795
          Length = 1239

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 692 MVVFITP 698
>XP_005245982
          Length = 1240

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 693 MVVFITP 699
>XP_005245981
          Length = 1241

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 694 MVVFITP 700
>XP_006710794
          Length = 1243

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 696 MVVFITP 702
>XP_006710793
          Length = 1243

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 696 MVVFITP 702
>XP_006710792
          Length = 1243

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 696 MVVFITP 702
>XP_006710791
          Length = 1244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 697 MVVFITP 703
>XP_006710790
          Length = 1244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 697 MVVFITP 703
>XP_005245980
          Length = 1244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           +VVF+TP
Sbjct: 697 MVVFITP 703
>NP_997465
          Length = 538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLVVFVTP 9
          LLLV+ +TP
Sbjct: 4  LLLVLILTP 12
>XP_006723231
          Length = 736

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LLLVVFVT 8
           +LL++FVT
Sbjct: 621 VLLIIFVT 628
>XP_005258877
          Length = 736

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LLLVVFVT 8
           +LL++FVT
Sbjct: 621 VLLIIFVT 628
>XP_005258876
          Length = 818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LLLVVFVT 8
           +LL++FVT
Sbjct: 703 VLLIIFVT 710
>NP_054756
          Length = 736

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LLLVVFVT 8
           +LL++FVT
Sbjct: 621 VLLIIFVT 628
>NP_112191
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLVVFVTP 9
          LLL+V +TP
Sbjct: 17 LLLLVVLTP 25
>NP_001074924
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLVVFVT 8
           LLL+VF T
Sbjct: 200 LLLIVFYT 207
>NP_066580
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLVVFVT 8
          LLL++FV+
Sbjct: 70 LLLIIFVS 77
>NP_060474
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLLVVFVT 8
           L+LVVF+T
Sbjct: 156 LVLVVFLT 163
>XP_005253535
          Length = 579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLVVFVT 8
          LLL++FV+
Sbjct: 68 LLLIIFVS 75
>XP_005253534
          Length = 650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLVVFVT 8
          LLL++FV+
Sbjct: 50 LLLIIFVS 57
>XP_005253531
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLVVFVT 8
          LLL++FV+
Sbjct: 70 LLLIIFVS 77
>XP_005270251
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLVVFVTP 9
          LLL+V +TP
Sbjct: 17 LLLLVVLTP 25
>XP_005270250
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLVVFVTP 9
          LLL+V +TP
Sbjct: 17 LLLLVVLTP 25
>XP_006713895
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLVVFVT 8
           LLL+VF T
Sbjct: 200 LLLIVFYT 207
>XP_005247980
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLVVFVT 8
           LLL+VF T
Sbjct: 200 LLLIVFYT 207
>XP_005247979
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLVVFVT 8
           LLL+VF T
Sbjct: 200 LLLIVFYT 207
>XP_005247978
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLVVFVT 8
           LLL+VF T
Sbjct: 200 LLLIVFYT 207
>XP_005247626
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLLVVFVT 8
           L+LVVF+T
Sbjct: 172 LVLVVFLT 179
>XP_005247625
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLLVVFVT 8
           L+LVVF+T
Sbjct: 172 LVLVVFLT 179
>NP_602307
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLVVFVT 8
          LLL++FV+
Sbjct: 70 LLLIIFVS 77
>NP_055694
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLVVFVT 8
           LLL+VF T
Sbjct: 200 LLLIVFYT 207
>NP_001165882
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           L+VF+TP
Sbjct: 119 LLVFLTP 125
>NP_001165883
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           L+VF+TP
Sbjct: 121 LLVFLTP 127
>NP_620409
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           L+VF+TP
Sbjct: 121 LLVFLTP 127
>NP_060341
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LVVFVTP 9
           +VVF TP
Sbjct: 319 MVVFATP 325
>NP_001243391
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LVVFVTP 9
           +VVF TP
Sbjct: 221 MVVFATP 227
>NP_001243389
          Length = 571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LVVFVTP 9
           +VVF TP
Sbjct: 290 MVVFATP 296
>NP_001243392
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LVVFVTP 9
           +VVF TP
Sbjct: 218 MVVFATP 224
>NP_001243385
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LVVFVTP 9
           +VVF TP
Sbjct: 325 MVVFATP 331
>XP_006710999
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LVVFVTP 9
          L+VF+TP
Sbjct: 60 LLVFLTP 66
>XP_006710998
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVVFVTP 9
           L+VF+TP
Sbjct: 121 LLVFLTP 127
>XP_005244820
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LVVFVTP 9
           +VVF TP
Sbjct: 221 MVVFATP 227
>XP_006710778
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LVVFVTP 9
           +VVF TP
Sbjct: 319 MVVFATP 325
>NP_001005323
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLLVVFV 7
           +LLVVFV
Sbjct: 197 MLLVVFV 203
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.161    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 383,454
Number of extensions: 728
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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