Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003671                                                              17    3301
NP_001269596                                                           17    3301
NP_001269595                                                           17    3301
XP_005253308                                                           17    3301
NP_001030014                                                           17    3301
NP_001230925                                                           17    4312
NP_073581                                                              17    4312
NP_002410                                                              17    4312
NP_001027                                                              17    4312
XP_005246213                                                           17    4312
XP_006711941                                                           17    4312
XP_006711940                                                           17    4312
XP_006711939                                                           17    4312
NP_036476                                                              17    4312
NP_057264                                                              16    5631
NP_000876                                                              16    5631
NP_060142                                                              16    5631
NP_001012527                                                           16    5631
NP_056046                                                              16    5631
XP_006720645                                                           16    5631
XP_005254546                                                           16    5631
XP_005254545                                                           16    5631
XP_005254544                                                           16    5631
XP_005254543                                                           16    5631
XP_006718233                                                           16    5631
XP_005248368                                                           16    5631
NP_001167630                                                           16    7355
NP_071354                                                              16    7355
NP_001167631                                                           16    7355
NP_003136                                                              16    7355
NP_001265585                                                           16    7355
NP_004166                                                              16    7355
NP_783165                                                              16    7355
NP_631900                                                              16    7355
NP_777377                                                              16    7355
NP_057594                                                              16    7355
XP_005259737                                                           16    7355
XP_006716441                                                           16    7355
NP_443095                                                              16    7355
NP_001161870                                                           15    9605
NP_006407                                                              15    9605
NP_001596                                                              15    9605
NP_002562                                                              15    9605
NP_001018059                                                           15    9605
NP_647479                                                              15    9605
NP_758963                                                              15    9605
NP_001846                                                              15    9605
NP_003728                                                              15    9605
NP_001265398                                                           15    9605
NP_001265400                                                           15    9605
NP_001265399                                                           15    9605
NP_001265401                                                           15    9605
NP_055841                                                              15    9605
NP_001662                                                              15    9605
NP_005294                                                              15    9605
XP_006726853                                                           15    9605
XP_003960484                                                           15    9605
XP_006723596                                                           15    9605
XP_006721216                                                           15    9605
XP_005268793                                                           15    9605
XP_005268792                                                           15    9605
XP_005268791                                                           15    9605
XP_005268789                                                           15    9605
XP_005268788                                                           15    9605
XP_005253264                                                           15    9605
XP_005263463                                                           15    9605
XP_005263462                                                           15    9605
XP_006717169                                                           15    9605
XP_001714084                                                           15    9605
XP_003120137                                                           15    9605
NP_001956                                                              15    9605
NP_001138526                                                           15    9605
NP_001001676                                                           15    9605
>NP_003671
          Length = 528

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLLSIGVPL 9
           +L SIGVPL
Sbjct: 104 MLESIGVPL 112
>NP_001269596
          Length = 955

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSIGVPL 9
           LLS+G+PL
Sbjct: 913 LLSLGLPL 920
>NP_001269595
          Length = 976

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSIGVPL 9
           LLS+G+PL
Sbjct: 934 LLSLGLPL 941
>XP_005253308
          Length = 1012

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSIGVPL 9
           LLS+G+PL
Sbjct: 970 LLSLGLPL 977
>NP_001030014
          Length = 767

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LLLSIGVP 8
           LLL IGVP
Sbjct: 432 LLLHIGVP 439
>NP_001230925
          Length = 4865

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LLLSIGVPL 9
            LLL  GVPL
Sbjct: 1903 LLLHCGVPL 1911
>NP_073581
          Length = 468

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LSIGVPL 9
           LS+GVPL
Sbjct: 327 LSLGVPL 333
>NP_002410
          Length = 847

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLLSIGVPL 9
           LLL +G+P+
Sbjct: 712 LLLDLGIPV 720
>NP_001027
          Length = 4870

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LLLSIGVPL 9
            LLL  GVPL
Sbjct: 1903 LLLHCGVPL 1911
>XP_005246213
          Length = 250

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL +GVP+
Sbjct: 81 LLLLVGVPV 89
>XP_006711941
          Length = 294

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL +GVP+
Sbjct: 81 LLLLVGVPV 89
>XP_006711940
          Length = 319

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL +GVP+
Sbjct: 81 LLLLVGVPV 89
>XP_006711939
          Length = 322

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL +GVP+
Sbjct: 81 LLLLVGVPV 89
>NP_036476
          Length = 410

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL +GVP+
Sbjct: 81 LLLLVGVPV 89
>NP_057264
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLSIGVP 8
          +LLS+G+P
Sbjct: 59 VLLSVGLP 66
>NP_000876
          Length = 1032

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LLLSIGVP 8
          LLL +GVP
Sbjct: 22 LLLCLGVP 29
>NP_060142
          Length = 1865

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLLSIGVP 8
            +LLS GVP
Sbjct: 1010 VLLSFGVP 1017
>NP_001012527
          Length = 460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLSIGVP 8
          +LLS+G+P
Sbjct: 59 VLLSVGLP 66
>NP_056046
          Length = 1436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LLSIGVPL 9
            LLS GVPL
Sbjct: 1314 LLSHGVPL 1321
>XP_006720645
          Length = 1060

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLLSIGVP 8
            +LLS GVP
Sbjct: 1010 VLLSFGVP 1017
>XP_005254546
          Length = 1443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLSIGVP 8
           +LLS GVP
Sbjct: 568 VLLSFGVP 575
>XP_005254545
          Length = 1864

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLLSIGVP 8
            +LLS GVP
Sbjct: 1010 VLLSFGVP 1017
>XP_005254544
          Length = 1884

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLLSIGVP 8
            +LLS GVP
Sbjct: 1010 VLLSFGVP 1017
>XP_005254543
          Length = 1885

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLLSIGVP 8
            +LLS GVP
Sbjct: 1010 VLLSFGVP 1017
>XP_006718233
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLSIGVPL 9
           LLS GVPL
Sbjct: 660 LLSHGVPL 667
>XP_005248368
          Length = 243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLSIGVP 8
          +LLS+G+P
Sbjct: 59 VLLSVGLP 66
>NP_001167630
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLSIGVP 8
           LLLS G+P
Sbjct: 360 LLLSTGMP 367
>NP_071354
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLSIGVP 8
           LLLS G+P
Sbjct: 360 LLLSTGMP 367
>NP_001167631
          Length = 409

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLSIGVP 8
           LLLS G+P
Sbjct: 315 LLLSTGMP 322
>NP_003136
          Length = 183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLSIGVPL 9
           L SIG+PL
Sbjct: 158 LPSIGIPL 165
>NP_001265585
          Length = 126

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3 LSIGVPL 9
         +SIGVP+
Sbjct: 1 MSIGVPI 7
>NP_004166
          Length = 126

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3 LSIGVPL 9
         +SIGVP+
Sbjct: 1 MSIGVPI 7
>NP_783165
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LLLSIGVP 8
          LLL +GVP
Sbjct: 22 LLLLLGVP 29
>NP_631900
          Length = 120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLSIGVP 8
          LLL++G+P
Sbjct: 8  LLLALGLP 15
>NP_777377
          Length = 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLSIGVP 8
          LLL++G+P
Sbjct: 8  LLLALGLP 15
>NP_057594
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLSIGVP 8
           +LLS GVP
Sbjct: 407 VLLSYGVP 414
>XP_005259737
          Length = 120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LLLSIGVP 8
          LLL++G+P
Sbjct: 8  LLLALGLP 15
>XP_006716441
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLSIGVP 8
           LLLS G+P
Sbjct: 333 LLLSTGMP 340
>NP_443095
          Length = 104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LL S+G+P+
Sbjct: 60 LLSSLGIPV 68
>NP_001161870
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLLSIGV 7
          LLLS+G+
Sbjct: 56 LLLSVGI 62
>NP_006407
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLLSIGV 7
          LLLS+G+
Sbjct: 56 LLLSVGI 62
>NP_001596
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LLSIGVPL 9
           ++SIGVP+
Sbjct: 696 VVSIGVPV 703
>NP_002562
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL++GV L
Sbjct: 4  LLLTLGVAL 12
>NP_001018059
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL++GV L
Sbjct: 4  LLLTLGVAL 12
>NP_647479
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LLLSIGVP 8
           L LSIG P
Sbjct: 392 LALSIGTP 399
>NP_758963
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LLLSIGVP 8
           L LSIG P
Sbjct: 392 LALSIGTP 399
>NP_001846
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLLSIGVPL 9
          +LLS+  PL
Sbjct: 15 MLLSVSTPL 23
>NP_003728
          Length = 3298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  LLLSIGVP 8
          LLL  GVP
Sbjct: 31 LLLGAGVP 38
>NP_001265398
          Length = 1675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1469 VLSIGLPV 1476
>NP_001265400
          Length = 1688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1440 VLSIGLPV 1447
>NP_001265399
          Length = 1711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1463 VLSIGLPV 1470
>NP_001265401
          Length = 1645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1397 VLSIGLPV 1404
>NP_055841
          Length = 1717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1469 VLSIGLPV 1476
>NP_001662
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLLS+G+ L
Sbjct: 42 LLLSLGLSL 50
>NP_005294
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL++ +PL
Sbjct: 53 LLLTVSLPL 61
>XP_006726853
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LLSIGVP 8
          LLS+G+P
Sbjct: 75 LLSLGLP 81
>XP_003960484
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLLSIGVPL 9
           LLL +G PL
Sbjct: 132 LLLVVGPPL 140
>XP_006723596
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LLSIGVP 8
          LLS+G+P
Sbjct: 75 LLSLGLP 81
>XP_006721216
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LLSIGVPL 9
           ++SIGVP+
Sbjct: 696 VVSIGVPV 703
>XP_005268793
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LLSIGVPL 9
           +LSIG+P+
Sbjct: 914 VLSIGLPV 921
>XP_005268792
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1398 VLSIGLPV 1405
>XP_005268791
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1398 VLSIGLPV 1405
>XP_005268789
          Length = 1712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1464 VLSIGLPV 1471
>XP_005268788
          Length = 1718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LLSIGVPL 9
            +LSIG+P+
Sbjct: 1470 VLSIGLPV 1477
>XP_005253264
          Length = 3443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LLLSIGVP 8
           LLL  GVP
Sbjct: 176 LLLGAGVP 183
>XP_005263463
          Length = 103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL++GV L
Sbjct: 4  LLLTLGVAL 12
>XP_005263462
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLL++GV L
Sbjct: 4  LLLTLGVAL 12
>XP_006717169
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLLS+G+ L
Sbjct: 4  LLLSLGLSL 12
>XP_001714084
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLLSIGVPL 9
           LLL +G PL
Sbjct: 132 LLLVVGPPL 140
>XP_003120137
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLLSIGVPL 9
           LLL +G PL
Sbjct: 132 LLLVVGPPL 140
>NP_001956
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LLSIGVP 8
           LLS+G P
Sbjct: 313 LLSVGAP 319
>NP_001138526
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LLLSIGVP 8
           +LLS GVP
Sbjct: 555 VLLSSGVP 562
>NP_001001676
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLLSIGVPL 9
          LLLS+G+ L
Sbjct: 4  LLLSLGLSL 12
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.160    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 587,332
Number of extensions: 1298
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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