Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     509
NP_001075109                                                           20     509
NP_079321                                                              17    4312
XP_005261808                                                           17    4312
NP_892006                                                              16    7355
NP_149062                                                              16    7355
NP_597721                                                              16    7355
NP_001007170                                                           16    7355
NP_665804                                                              16    7355
NP_006715                                                              16    7355
NP_005913                                                              16    7355
NP_002193                                                              16    7355
XP_006726495                                                           16    7355
XP_005276346                                                           16    7355
XP_003961039                                                           16    7355
XP_005271850                                                           16    7355
XP_005267046                                                           16    7355
XP_005267045                                                           16    7355
XP_006715488                                                           16    7355
XP_006715487                                                           16    7355
XP_006715486                                                           16    7355
XP_006715485                                                           16    7355
XP_006715484                                                           16    7355
XP_006715483                                                           16    7355
XP_006715482                                                           16    7355
XP_006715481                                                           16    7355
XP_006715480                                                           16    7355
XP_006715479                                                           16    7355
XP_006715478                                                           16    7355
XP_006715477                                                           16    7355
XP_006715476                                                           16    7355
XP_006715475                                                           16    7355
XP_006715474                                                           16    7355
XP_006715473                                                           16    7355
XP_006715472                                                           16    7355
XP_006715471                                                           16    7355
XP_006715470                                                           16    7355
NP_001008711                                                           15    9605
NP_001008710                                                           15    9605
NP_006858                                                              15    9605
NP_001008712                                                           15    9605
XP_005273447                                                           15    9605
XP_005273443                                                           15    9605
XP_006716342                                                           15    9605
XP_006716341                                                           15    9605
XP_006716340                                                           15    9605
XP_005246783                                                           15    9605
NP_065994                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLKMTSMSP 9
            LL+MTSMSP
Sbjct: 2562 LLEMTSMSP 2570
>NP_001075109
          Length = 4097

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLKMTSMSP 9
            LL+MTSMSP
Sbjct: 2562 LLEMTSMSP 2570
>NP_079321
          Length = 529

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLKMTSMSP 9
           +  MTSMSP
Sbjct: 399 MTSMTSMSP 407
>XP_005261808
          Length = 529

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLKMTSMSP 9
           +  MTSMSP
Sbjct: 399 MTSMTSMSP 407
>NP_892006
          Length = 8797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7400 MLKFSSMAP 7408
>NP_149062
          Length = 8749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7329 MLKFSSMAP 7337
>NP_597721
          Length = 744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLKMTSMSP 9
          L KMT++SP
Sbjct: 7  LNKMTAISP 15
>NP_001007170
          Length = 256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLKMTSMSP 9
          L KMT++SP
Sbjct: 7  LNKMTAISP 15
>NP_665804
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLKMTSMSP 9
           L++MT +SP
Sbjct: 224 LVEMTGLSP 232
>NP_006715
          Length = 1558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLKMTSMS 8
           LLK+TS+S
Sbjct: 232 LLKLTSVS 239
>NP_005913
          Length = 1608

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLKMTSMS 8
           LLK+TS+S
Sbjct: 232 LLKLTSVS 239
>NP_002193
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLKMTSMSP 9
           L++MT +SP
Sbjct: 214 LVEMTGLSP 222
>XP_006726495
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLKMTSMSP 9
           LLK+TS  P
Sbjct: 253 LLKLTSPGP 261
>XP_005276346
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLKMTSMSP 9
           LLK+TS  P
Sbjct: 226 LLKLTSPGP 234
>XP_003961039
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLKMTSMSP 9
           LLK+TS  P
Sbjct: 253 LLKLTSPGP 261
>XP_005271850
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLKMTSMSP 9
           LLK+TS  P
Sbjct: 226 LLKLTSPGP 234
>XP_005267046
          Length = 1554

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLKMTSMS 8
           LLK+TS+S
Sbjct: 232 LLKLTSVS 239
>XP_005267045
          Length = 1604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLKMTSMS 8
           LLK+TS+S
Sbjct: 232 LLKLTSVS 239
>XP_006715488
          Length = 8721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7412 MLKFSSMAP 7420
>XP_006715487
          Length = 8744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7412 MLKFSSMAP 7420
>XP_006715486
          Length = 8758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7412 MLKFSSMAP 7420
>XP_006715485
          Length = 8793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7359 MLKFSSMAP 7367
>XP_006715484
          Length = 8794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7360 MLKFSSMAP 7368
>XP_006715483
          Length = 8795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7361 MLKFSSMAP 7369
>XP_006715482
          Length = 8797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7400 MLKFSSMAP 7408
>XP_006715481
          Length = 8799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7365 MLKFSSMAP 7373
>XP_006715480
          Length = 8799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7365 MLKFSSMAP 7373
>XP_006715479
          Length = 8804

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7407 MLKFSSMAP 7415
>XP_006715478
          Length = 8809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7412 MLKFSSMAP 7420
>XP_006715477
          Length = 8822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7388 MLKFSSMAP 7396
>XP_006715476
          Length = 8823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7412 MLKFSSMAP 7420
>XP_006715475
          Length = 8827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7407 MLKFSSMAP 7415
>XP_006715474
          Length = 8829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7395 MLKFSSMAP 7403
>XP_006715473
          Length = 8832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7412 MLKFSSMAP 7420
>XP_006715472
          Length = 8839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7405 MLKFSSMAP 7413
>XP_006715471
          Length = 8842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7408 MLKFSSMAP 7416
>XP_006715470
          Length = 8846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LLKMTSMSP 9
            +LK +SM+P
Sbjct: 7412 MLKFSSMAP 7420
>NP_001008711
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>NP_001008710
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>NP_006858
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>NP_001008712
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>XP_005273447
          Length = 136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>XP_005273443
          Length = 179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>XP_006716342
          Length = 186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>XP_006716341
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>XP_006716340
          Length = 224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLKMTSMSP 9
          L+K+TS  P
Sbjct: 54 LIKLTSKQP 62
>XP_005246783
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKMTSMSP 9
           LK+T +SP
Sbjct: 302 LKLTQVSP 309
>NP_065994
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LKMTSMSP 9
           LK+T +SP
Sbjct: 302 LKLTQVSP 309
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.119    0.306 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 332,063
Number of extensions: 552
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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