Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000360                                                              19     869
XP_005268094                                                           19     869
NP_056161                                                              17    2528
XP_006720156                                                           17    2528
NP_000278                                                              16    5631
NP_852111                                                              16    5631
NP_000136                                                              16    5631
XP_005249237                                                           16    5631
XP_005245794                                                           16    5631
XP_005245795                                                           16    5631
XP_005245793                                                           16    5631
NP_001832                                                              16    5631
NP_057332                                                              16    7355
NP_006085                                                              16    7355
NP_001157743                                                           16    7355
NP_872584                                                              16    7355
NP_001136069                                                           16    7355
XP_005276467                                                           16    7355
XP_005266305                                                           16    7355
XP_005266304                                                           16    7355
XP_006718488                                                           16    7355
XP_005273432                                                           16    7355
XP_005273431                                                           16    7355
NP_006822                                                              16    7355
NP_073744                                                              15    9605
NP_001030611                                                           15    9605
XP_005252192                                                           15    9605
NP_076411                                                              15    9605
>NP_000360
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LLI SVDLY
Sbjct: 468 LLIASVDLY 476
>XP_005268094
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LLI SVDLY
Sbjct: 468 LLIASVDLY 476
>NP_056161
          Length = 2539

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LLITS DL+
Sbjct: 582 LLITSADLH 590
>XP_006720156
          Length = 2497

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LLITS DL+
Sbjct: 582 LLITSADLH 590
>NP_000278
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLITSVDL 8
           LL+T+VDL
Sbjct: 526 LLLTAVDL 533
>NP_852111
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LLI SVD++
Sbjct: 390 LLIASVDIH 398
>NP_000136
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LLI SVD++
Sbjct: 416 LLIASVDIH 424
>XP_005249237
          Length = 892

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLITSVDL 8
           LL+T+VDL
Sbjct: 438 LLLTAVDL 445
>XP_005245794
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LL+T++D Y
Sbjct: 124 LLLTAIDRY 132
>XP_005245795
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LL+T++D Y
Sbjct: 124 LLLTAIDRY 132
>XP_005245793
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LL+T++D Y
Sbjct: 124 LLLTAIDRY 132
>NP_001832
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LL+T++D Y
Sbjct: 124 LLLTAIDRY 132
>NP_057332
          Length = 1901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LLITSVDL 8
            LLIT++D+
Sbjct: 1810 LLITNIDM 1817
>NP_006085
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLITSVD 7
            LL+TSVD
Sbjct: 1007 LLLTSVD 1013
>NP_001157743
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLITSVD 7
           LL+TSVD
Sbjct: 933 LLLTSVD 939
>NP_872584
          Length = 1528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLITSVD 7
            LL+TSVD
Sbjct: 1444 LLLTSVD 1450
>NP_001136069
          Length = 361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LLITSVDL 8
           +++TSVDL
Sbjct: 323 IVVTSVDL 330
>XP_005276467
          Length = 97

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LITSVDL 8
          L+TSVDL
Sbjct: 54 LLTSVDL 60
>XP_005266305
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LLITSVDL 8
            LLIT++D+
Sbjct: 1765 LLITNIDM 1772
>XP_005266304
          Length = 1873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LLITSVDL 8
            LLIT++D+
Sbjct: 1782 LLITNIDM 1789
>XP_006718488
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LLITSVDL 8
           +++TSVDL
Sbjct: 387 IVVTSVDL 394
>XP_005273432
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLITSVD 7
            LL+TSVD
Sbjct: 1041 LLLTSVD 1047
>XP_005273431
          Length = 1528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LLITSVD 7
            LL+TSVD
Sbjct: 1444 LLLTSVD 1450
>NP_006822
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LLITSVDL 8
           +++TSVDL
Sbjct: 387 IVVTSVDL 394
>NP_073744
          Length = 746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LITSVDLY 9
           ++TSVD Y
Sbjct: 124 ILTSVDQY 131
>NP_001030611
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LITSVDLY 9
           ++TSVD Y
Sbjct: 111 ILTSVDQY 118
>XP_005252192
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LITSVDLY 9
           ++TSVD Y
Sbjct: 113 ILTSVDQY 120
>NP_076411
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLITSVDLY 9
           LL+TSV L+
Sbjct: 134 LLVTSVFLF 142
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.150    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 402,802
Number of extensions: 526
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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