Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              20     390
NP_444254                                                              20     390
NP_444253                                                              20     390
NP_444255                                                              20     390
XP_005247551                                                           20     390
XP_005247550                                                           20     390
XP_006713712                                                           20     390
XP_005247549                                                           20     390
NP_079452                                                              18    1935
XP_006723617                                                           18    1935
XP_005260737                                                           18    1935
XP_006723616                                                           18    1935
XP_006723615                                                           18    1935
XP_005260735                                                           18    1935
NP_001269676                                                           17    3301
NP_001269675                                                           17    3301
NP_001269674                                                           17    3301
NP_775104                                                              17    3301
XP_005252438                                                           17    3301
XP_005252437                                                           17    3301
XP_006721386                                                           16    5631
NP_998725                                                              16    7355
NP_002732                                                              16    7355
NP_001070884                                                           15    9605
NP_001245308                                                           15    9605
NP_003606                                                              15    9605
NP_001245309                                                           15    9605
NP_001243000                                                           15    9605
NP_067028                                                              15    9605
NP_683699                                                              15    9605
NP_001070886                                                           15    9605
NP_004186                                                              15    9605
NP_683700                                                              15    9605
NP_001171486                                                           15    9605
NP_001245330                                                           15    9605
NP_001035049                                                           15    9605
NP_671766                                                              15    9605
NP_671756                                                              15    9605
NP_001171487                                                           15    9605
NP_003734                                                              15    9605
NP_001245331                                                           15    9605
NP_078928                                                              15    9605
NP_001245332                                                           15    9605
NP_001254544                                                           15    9605
XP_005257603                                                           15    9605
XP_006722058                                                           15    9605
XP_005257602                                                           15    9605
XP_005255036                                                           15    9605
XP_006719764                                                           15    9605
XP_006719763                                                           15    9605
XP_005265658                                                           15    9605
XP_005265657                                                           15    9605
XP_005265656                                                           15    9605
XP_005265655                                                           15    9605
XP_006713484                                                           15    9605
XP_005246753                                                           15    9605
XP_005246752                                                           15    9605
XP_005246751                                                           15    9605
XP_006712706                                                           15    9605
XP_006712705                                                           15    9605
XP_006712704                                                           15    9605
XP_005246750                                                           15    9605
XP_006712189                                                           15    9605
XP_005264685                                                           15    9605
XP_005264684                                                           15    9605
XP_005264683                                                           15    9605
XP_005264682                                                           15    9605
NP_071341                                                              15    9605
NP_699191                                                              15    9605
>NP_444256
          Length = 1794

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLGTESDAT 9
            +LGTESDAT
Sbjct: 1144 VLGTESDAT 1152
>NP_444254
          Length = 1845

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLGTESDAT 9
            +LGTESDAT
Sbjct: 1144 VLGTESDAT 1152
>NP_444253
          Length = 1914

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLGTESDAT 9
            +LGTESDAT
Sbjct: 1213 VLGTESDAT 1221
>NP_444255
          Length = 1863

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLGTESDAT 9
            +LGTESDAT
Sbjct: 1213 VLGTESDAT 1221
>XP_005247551
          Length = 1855

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLGTESDAT 9
            +LGTESDAT
Sbjct: 1154 VLGTESDAT 1162
>XP_005247550
          Length = 1856

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLGTESDAT 9
            +LGTESDAT
Sbjct: 1223 VLGTESDAT 1231
>XP_006713712
          Length = 1923

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLGTESDAT 9
            +LGTESDAT
Sbjct: 1223 VLGTESDAT 1231
>XP_005247549
          Length = 1924

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLGTESDAT 9
            +LGTESDAT
Sbjct: 1223 VLGTESDAT 1231
>NP_079452
          Length = 1382

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLGTE DA+
Sbjct: 943 LLGTERDAS 951
>XP_006723617
          Length = 762

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLGTE DA+
Sbjct: 323 LLGTERDAS 331
>XP_005260737
          Length = 1015

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLGTE DA+
Sbjct: 576 LLGTERDAS 584
>XP_006723616
          Length = 1223

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLGTE DA+
Sbjct: 784 LLGTERDAS 792
>XP_006723615
          Length = 1382

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLGTE DA+
Sbjct: 943 LLGTERDAS 951
>XP_005260735
          Length = 1398

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLGTE DA+
Sbjct: 959 LLGTERDAS 967
>NP_001269676
          Length = 609

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LLGTESDAT 9
          LLG+E+D T
Sbjct: 61 LLGSENDGT 69
>NP_001269675
          Length = 688

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLG+E+D T
Sbjct: 324 LLGSENDGT 332
>NP_001269674
          Length = 865

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLG+E+D T
Sbjct: 324 LLGSENDGT 332
>NP_775104
          Length = 872

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLG+E+D T
Sbjct: 324 LLGSENDGT 332
>XP_005252438
          Length = 784

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLG+E+D T
Sbjct: 236 LLGSENDGT 244
>XP_005252437
          Length = 807

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLGTESDAT 9
           LLG+E+D T
Sbjct: 259 LLGSENDGT 267
>XP_006721386
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GTESDAT 9
           G ESDAT
Sbjct: 227 GAESDAT 233
>NP_998725
          Length = 948

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LGTESDAT 9
           LGT+SD++
Sbjct: 561 LGTDSDSS 568
>NP_002732
          Length = 942

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LGTESDAT 9
           LGT+SD++
Sbjct: 555 LGTDSDSS 562
>NP_001070884
          Length = 369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           LLG ESD
Sbjct: 125 LLGPESD 131
>NP_001245308
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEDD 108
>NP_003606
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 97  ILGTEDD 103
>NP_001245309
          Length = 1090

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 97  ILGTEDD 103
>NP_001243000
          Length = 5207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLGTES 6
            LLGTES
Sbjct: 3934 LLGTES 3939
>NP_067028
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LLGTESD 7
           L+GT+SD
Sbjct: 158 LVGTQSD 164
>NP_683699
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LLGTESDA 8
          LLGT +DA
Sbjct: 40 LLGTGTDA 47
>NP_001070886
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  LLGTESD 7
          LLG ESD
Sbjct: 72 LLGPESD 78
>NP_004186
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LLGTESDA 8
          LLGT +DA
Sbjct: 40 LLGTGTDA 47
>NP_683700
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LLGTESDA 8
          LLGT +DA
Sbjct: 40 LLGTGTDA 47
>NP_001171486
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEDD 108
>NP_001245330
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LLGTESD 7
          +LGTE D
Sbjct: 49 ILGTEED 55
>NP_001035049
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEED 108
>NP_671766
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLGTESDAT 9
            LL TE+D T
Sbjct: 1376 LLKTEADGT 1384
>NP_671756
          Length = 1399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLGTESDAT 9
            LL TE+D T
Sbjct: 1376 LLKTEADGT 1384
>NP_001171487
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 113 ILGTEDD 119
>NP_003734
          Length = 1441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLGTESDAT 9
            LL TE+D T
Sbjct: 1376 LLKTEADGT 1384
>NP_001245331
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEED 108
>NP_078928
          Length = 2015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    LLGTESDAT 9
            L  TESD T
Sbjct: 1148 LTATESDGT 1156
>NP_001245332
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LLGTESD 7
          +LGTE D
Sbjct: 49 ILGTEED 55
>NP_001254544
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  LLGTESD 7
          +LGTE D
Sbjct: 49 ILGTEED 55
>XP_005257603
          Length = 5256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLGTES 6
            LLGTES
Sbjct: 3983 LLGTES 3988
>XP_006722058
          Length = 5256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLGTES 6
            LLGTES
Sbjct: 3983 LLGTES 3988
>XP_005257602
          Length = 5256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LLGTES 6
            LLGTES
Sbjct: 3983 LLGTES 3988
>XP_005255036
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LLGTESDAT 9
           L  TESD T
Sbjct: 443 LTATESDGT 451
>XP_006719764
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEED 108
>XP_006719763
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEED 108
>XP_005265658
          Length = 1095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEDD 108
>XP_005265657
          Length = 1113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 97  ILGTEDD 103
>XP_005265656
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEDD 108
>XP_005265655
          Length = 1126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 97  ILGTEDD 103
>XP_006713484
          Length = 1255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEDD 108
>XP_005246753
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 171 ILGTEDD 177
>XP_005246752
          Length = 1117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 113 ILGTEDD 119
>XP_005246751
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 113 ILGTEDD 119
>XP_006712706
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 114 ILGTEDD 120
>XP_006712705
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 171 ILGTEDD 177
>XP_006712704
          Length = 1204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 171 ILGTEDD 177
>XP_005246750
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 171 ILGTEDD 177
>XP_006712189
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLGTESDAT 9
            LL TE+D T
Sbjct: 1329 LLKTEADGT 1337
>XP_005264685
          Length = 1399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLGTESDAT 9
            LL TE+D T
Sbjct: 1376 LLKTEADGT 1384
>XP_005264684
          Length = 1399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLGTESDAT 9
            LL TE+D T
Sbjct: 1376 LLKTEADGT 1384
>XP_005264683
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLGTESDAT 9
            LL TE+D T
Sbjct: 1376 LLKTEADGT 1384
>XP_005264682
          Length = 1441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLGTESDAT 9
            LL TE+D T
Sbjct: 1376 LLKTEADGT 1384
>NP_071341
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LLGTESD 7
           +LGTE D
Sbjct: 102 ILGTEDD 108
>NP_699191
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LGTESDAT 9
           +GTE D T
Sbjct: 387 MGTERDVT 394
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.120    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 585,495
Number of extensions: 1299
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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