Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     665
NP_001035957                                                           19     665
XP_006721991                                                           19     665
XP_006721990                                                           19     665
XP_006721989                                                           19     665
XP_005258041                                                           19     665
XP_006721988                                                           19     665
XP_006721987                                                           19     665
XP_006721986                                                           19     665
XP_005258040                                                           19     665
XP_006721985                                                           19     665
NP_078934                                                              18    1482
NP_065802                                                              17    3301
NP_001138551                                                           17    3301
NP_068741                                                              17    4312
NP_056169                                                              17    4312
NP_060972                                                              17    4312
NP_997051                                                              17    4312
XP_005248945                                                           17    4312
XP_005248944                                                           17    4312
XP_005248943                                                           17    4312
XP_005248942                                                           17    4312
XP_005268534                                                           17    4312
XP_005268533                                                           17    4312
NP_940982                                                              16    5631
NP_036257                                                              16    5631
NP_001070254                                                           16    5631
XP_006722812                                                           16    5631
XP_005254198                                                           16    5631
XP_006718388                                                           16    5631
XP_006718387                                                           16    5631
XP_006718386                                                           16    5631
NP_079108                                                              16    7355
NP_001271426                                                           16    7355
NP_114428                                                              16    7355
NP_001014980                                                           16    7355
XP_005255680                                                           16    7355
XP_006721020                                                           16    7355
XP_005255679                                                           16    7355
XP_006721019                                                           16    7355
NP_653203                                                              16    7355
NP_940820                                                              15    9605
NP_001005493                                                           15    9605
NP_001028776                                                           15    9605
NP_001028777                                                           15    9605
NP_055266                                                              15    9605
NP_004963                                                              15    9605
NP_001161302                                                           15    9605
NP_477352                                                              15    9605
NP_056509                                                              15    9605
NP_705618                                                              15    9605
NP_006081                                                              15    9605
NP_005348                                                              15    9605
NP_004289                                                              15    9605
NP_001007795                                                           15    9605
NP_001265241                                                           15    9605
NP_001230466                                                           15    9605
XP_005261692                                                           15    9605
XP_005261691                                                           15    9605
XP_005261297                                                           15    9605
XP_005258998                                                           15    9605
XP_006723281                                                           15    9605
XP_005258997                                                           15    9605
XP_005258996                                                           15    9605
XP_005258995                                                           15    9605
XP_005251512                                                           15    9605
XP_005250038                                                           15    9605
XP_005250037                                                           15    9605
XP_005249758                                                           15    9605
XP_005249757                                                           15    9605
XP_006715750                                                           15    9605
XP_006710349                                                           15    9605
XP_005270410                                                           15    9605
XP_006710348                                                           15    9605
>NP_000258
          Length = 2818

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1300 LLDPLLRIV 1308
>NP_001035957
          Length = 2839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1300 LLDPLLRIV 1308
>XP_006721991
          Length = 1632

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1310 LLDPLLRIV 1318
>XP_006721990
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1310 LLDPLLRIV 1318
>XP_006721989
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1310 LLDPLLRIV 1318
>XP_005258041
          Length = 2836

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1300 LLDPLLRIV 1308
>XP_006721988
          Length = 2846

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1310 LLDPLLRIV 1318
>XP_006721987
          Length = 2849

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1310 LLDPLLRIV 1318
>XP_006721986
          Length = 2854

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1297 LLDPLLRIV 1305
>XP_005258040
          Length = 2857

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1300 LLDPLLRIV 1308
>XP_006721985
          Length = 2867

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LLDPLLQIV 9
            LLDPLL+IV
Sbjct: 1310 LLDPLLRIV 1318
>NP_078934
          Length = 1081

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LLDPLLQIV 9
           LL PLLQIV
Sbjct: 391 LLPPLLQIV 399
>NP_065802
          Length = 657

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLDPLLQI 8
           +LDPLLQ+
Sbjct: 477 VLDPLLQM 484
>NP_001138551
          Length = 615

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLDPLLQI 8
           +LDPLLQ+
Sbjct: 477 VLDPLLQM 484
>NP_068741
          Length = 536

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLDPLLQ 7
           LLDP+LQ
Sbjct: 402 LLDPVLQ 408
>NP_056169
          Length = 1749

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLDPLLQIV 9
           LL PLLQ++
Sbjct: 443 LLSPLLQLL 451
>NP_060972
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLDPLLQIV 9
           L++PLLQ++
Sbjct: 383 LIEPLLQLL 391
>NP_997051
          Length = 105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LLDPLLQIV 9
          LLDP L+++
Sbjct: 86 LLDPFLEVL 94
>XP_005248945
          Length = 451

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLDPLLQ 7
           LLDP+LQ
Sbjct: 402 LLDPVLQ 408
>XP_005248944
          Length = 494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLDPLLQ 7
           LLDP+LQ
Sbjct: 402 LLDPVLQ 408
>XP_005248943
          Length = 513

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLDPLLQ 7
           LLDP+LQ
Sbjct: 379 LLDPVLQ 385
>XP_005248942
          Length = 529

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLDPLLQ 7
           LLDP+LQ
Sbjct: 395 LLDPVLQ 401
>XP_005268534
          Length = 494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLDPLLQIV 9
           L++PLLQ++
Sbjct: 384 LIEPLLQLL 392
>XP_005268533
          Length = 499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LLDPLLQIV 9
           L++PLLQ++
Sbjct: 389 LIEPLLQLL 397
>NP_940982
          Length = 646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLDPLLQ 7
           LLDPLL+
Sbjct: 219 LLDPLLK 225
>NP_036257
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DPLLQIV 9
           DP+LQ+V
Sbjct: 318 DPVLQVV 324
>NP_001070254
          Length = 1735

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DPLLQI 8
           DPLLQI
Sbjct: 97  DPLLQI 102
>XP_006722812
          Length = 673

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLDPLLQ 7
           LLDPLL+
Sbjct: 246 LLDPLLK 252
>XP_005254198
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DPLLQIV 9
           DP+LQ+V
Sbjct: 318 DPVLQVV 324
>XP_006718388
          Length = 1331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DPLLQI 8
           DPLLQI
Sbjct: 160 DPLLQI 165
>XP_006718387
          Length = 1798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DPLLQI 8
           DPLLQI
Sbjct: 160 DPLLQI 165
>XP_006718386
          Length = 1822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DPLLQI 8
           DPLLQI
Sbjct: 160 DPLLQI 165
>NP_079108
          Length = 985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           L+DP LQ+
Sbjct: 813 LMDPALQL 820
>NP_001271426
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           +L PLLQ+
Sbjct: 209 ILSPLLQV 216
>NP_114428
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           +L PLLQ+
Sbjct: 209 ILSPLLQV 216
>NP_001014980
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LLDPLL 6
           LLDPLL
Sbjct: 136 LLDPLL 141
>XP_005255680
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           +L PLLQ+
Sbjct: 200 ILSPLLQV 207
>XP_006721020
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           +L PLLQ+
Sbjct: 209 ILSPLLQV 216
>XP_005255679
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           +L PLLQ+
Sbjct: 209 ILSPLLQV 216
>XP_006721019
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           +L PLLQ+
Sbjct: 209 ILSPLLQV 216
>NP_653203
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LLDPLLQ 7
           +LDP+LQ
Sbjct: 156 VLDPMLQ 162
>NP_940820
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LLDPLLQI 8
          L DP+LQ+
Sbjct: 74 LRDPVLQV 81
>NP_001005493
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  DPLLQIV 9
          DP LQIV
Sbjct: 18 DPQLQIV 24
>NP_001028776
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LLDPLLQI 8
          L DP+LQ+
Sbjct: 74 LRDPVLQV 81
>NP_001028777
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LLDPLLQI 8
          L DP+LQ+
Sbjct: 74 LRDPVLQV 81
>NP_055266
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LLDPLLQI 8
          L DP+LQ+
Sbjct: 74 LRDPVLQV 81
>NP_004963
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  LDPLLQI 8
          +DP+LQ+
Sbjct: 35 IDPVLQV 41
>NP_001161302
          Length = 193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LLDPLLQI 8
           +LDP+++I
Sbjct: 156 ILDPIIKI 163
>NP_477352
          Length = 2102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LLDPLLQIV 9
           +++P+LQI+
Sbjct: 633 VMEPILQIL 641
>NP_056509
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LDPLLQ 7
           +DPLLQ
Sbjct: 151 MDPLLQ 156
>NP_705618
          Length = 1391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DPLLQI 8
           DP+LQI
Sbjct: 277 DPILQI 282
>NP_006081
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLDPLLQ 7
          LL+PL+Q
Sbjct: 63 LLEPLMQ 69
>NP_005348
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           L+DPLL +
Sbjct: 770 LMDPLLPL 777
>NP_004289
          Length = 1332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DPLLQI 8
           DP+LQI
Sbjct: 218 DPILQI 223
>NP_001007795
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLDPLLQ 7
          LL+PL+Q
Sbjct: 63 LLEPLMQ 69
>NP_001265241
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DPLLQI 8
           DP+LQI
Sbjct: 277 DPILQI 282
>NP_001230466
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           LLDP L++
Sbjct: 129 LLDPFLRL 136
>XP_005261692
          Length = 1854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LLDPLLQIV 9
           +++P+LQI+
Sbjct: 661 VMEPILQIL 669
>XP_005261691
          Length = 2099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   LLDPLLQIV 9
           +++P+LQI+
Sbjct: 661 VMEPILQIL 669
>XP_005261297
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           LLDP L++
Sbjct: 387 LLDPFLRL 394
>XP_005258998
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           L+DPLL +
Sbjct: 469 LMDPLLPL 476
>XP_006723281
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           L+DPLL +
Sbjct: 469 LMDPLLPL 476
>XP_005258997
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           L+DPLL +
Sbjct: 469 LMDPLLPL 476
>XP_005258996
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           L+DPLL +
Sbjct: 480 LMDPLLPL 487
>XP_005258995
          Length = 821

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LLDPLLQI 8
           L+DPLL +
Sbjct: 515 LMDPLLPL 522
>XP_005251512
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  LDPLLQI 8
          +DP+LQ+
Sbjct: 35 IDPVLQV 41
>XP_005250038
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LDPLLQ 7
           +DPLLQ
Sbjct: 151 MDPLLQ 156
>XP_005250037
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LDPLLQ 7
           +DPLLQ
Sbjct: 195 MDPLLQ 200
>XP_005249758
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LLDPLLQI 8
          L DP+LQ+
Sbjct: 74 LRDPVLQV 81
>XP_005249757
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LLDPLLQI 8
          L DP+LQ+
Sbjct: 74 LRDPVLQV 81
>XP_006715750
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LLDPLLQI 8
          L DP+LQ+
Sbjct: 74 LRDPVLQV 81
>XP_006710349
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLDPLLQ 7
          LL+PL+Q
Sbjct: 63 LLEPLMQ 69
>XP_005270410
          Length = 268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLDPLLQ 7
          LL+PL+Q
Sbjct: 63 LLEPLMQ 69
>XP_006710348
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LLDPLLQ 7
          LL+PL+Q
Sbjct: 63 LLEPLMQ 69
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.162    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 658,680
Number of extensions: 984
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package