Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1935
NP_671714                                                              18    1935
XP_006715890                                                           18    1935
XP_005250160                                                           18    1935
XP_005250159                                                           18    1935
NP_619635                                                              17    3301
NP_056372                                                              17    4312
NP_005843                                                              17    4312
NP_001005273                                                           17    4312
NP_001264                                                              17    4312
XP_006721493                                                           17    4312
XP_006721492                                                           17    4312
XP_006721491                                                           17    4312
XP_006721490                                                           17    4312
XP_006721489                                                           17    4312
XP_006721488                                                           17    4312
XP_005256486                                                           17    4312
XP_005256485                                                           17    4312
XP_006721487                                                           17    4312
XP_006721486                                                           17    4312
XP_005256484                                                           17    4312
XP_006719025                                                           17    4312
XP_005253725                                                           17    4312
XP_006719024                                                           17    4312
XP_006719023                                                           17    4312
XP_006719022                                                           17    4312
XP_006719021                                                           17    4312
NP_001005271                                                           17    4312
NP_001138818                                                           16    5631
NP_055838                                                              16    5631
NP_003732                                                              16    5631
NP_001263181                                                           16    5631
XP_005257123                                                           16    5631
XP_005247908                                                           16    5631
XP_005247907                                                           16    5631
XP_005247906                                                           16    5631
XP_005247905                                                           16    5631
NP_055951                                                              16    7355
XP_006713129                                                           16    7355
XP_006713128                                                           16    7355
XP_005265032                                                           16    7355
XP_005265031                                                           16    7355
XP_005265030                                                           16    7355
NP_001367                                                              15    9605
NP_001923                                                              15    9605
NP_001002264                                                           15    9605
NP_150280                                                              15    9605
NP_059119                                                              15    9605
NP_001348                                                              15    9605
NP_942016                                                              15    9605
NP_057535                                                              15    9605
NP_001137534                                                           15    9605
NP_001137533                                                           15    9605
XP_006723937                                                           15    9605
XP_006723936                                                           15    9605
XP_005260286                                                           15    9605
XP_006721980                                                           15    9605
XP_006721978                                                           15    9605
XP_006719959                                                           15    9605
XP_005266654                                                           15    9605
XP_005266653                                                           15    9605
XP_005263119                                                           15    9605
NP_003186                                                              15    9605
>NP_005742
          Length = 3907

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LLARMGG 7
            LLARMGG
Sbjct: 3739 LLARMGG 3745
>NP_671714
          Length = 3899

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LLARMGG 7
            LLARMGG
Sbjct: 3731 LLARMGG 3737
>XP_006715890
          Length = 3860

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LLARMGG 7
            LLARMGG
Sbjct: 3692 LLARMGG 3698
>XP_005250160
          Length = 3939

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LLARMGG 7
            LLARMGG
Sbjct: 3771 LLARMGG 3777
>XP_005250159
          Length = 3952

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LLARMGG 7
            LLARMGG
Sbjct: 3784 LLARMGG 3790
>NP_619635
          Length = 1043

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LLARMGGS 8
          +LAR+GGS
Sbjct: 29 VLARLGGS 36
>NP_056372
          Length = 1954

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1411 LLARVGGN 1418
>NP_005843
          Length = 1966

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1399 LLARVGGN 1406
>NP_001005273
          Length = 2000

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1399 LLARVGGN 1406
>NP_001264
          Length = 1912

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1403 LLARVGGN 1410
>XP_006721493
          Length = 2056

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1454 LLARVGGN 1461
>XP_006721492
          Length = 1924

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006721491
          Length = 2025

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006721490
          Length = 2036

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1379 LLARVGGN 1386
>XP_006721489
          Length = 2045

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006721488
          Length = 2056

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1399 LLARVGGN 1406
>XP_005256486
          Length = 2060

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_005256485
          Length = 2080

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006721487
          Length = 2111

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1454 LLARVGGN 1461
>XP_006721486
          Length = 2114

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_005256484
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006719025
          Length = 1902

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1390 LLARVGGN 1397
>XP_005253725
          Length = 1905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1396 LLARVGGN 1403
>XP_006719024
          Length = 1908

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1396 LLARVGGN 1403
>XP_006719023
          Length = 1914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1402 LLARVGGN 1409
>XP_006719022
          Length = 1915

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1403 LLARVGGN 1410
>XP_006719021
          Length = 1940

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1431 LLARVGGN 1438
>NP_001005271
          Length = 2059

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LLARMGGS 8
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>NP_001138818
          Length = 1067

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LARMGGS 8
           LAR+GGS
Sbjct: 213 LARIGGS 219
>NP_055838
          Length = 676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LLARMGGSQ 9
           LL  MGG Q
Sbjct: 283 LLVNMGGEQ 291
>NP_003732
          Length = 955

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLARMGGSQ 9
           LLA +GGS+
Sbjct: 570 LLAGLGGSE 578
>NP_001263181
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LLARMGGSQ 9
           LL  MGG Q
Sbjct: 283 LLVNMGGEQ 291
>XP_005257123
          Length = 803

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARMGGS 8
           ARMGGS
Sbjct: 209 ARMGGS 214
>XP_005247908
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLARMGGSQ 9
           LLA +GGS+
Sbjct: 597 LLAGLGGSE 605
>XP_005247907
          Length = 954

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLARMGGSQ 9
           LLA +GGS+
Sbjct: 570 LLAGLGGSE 578
>XP_005247906
          Length = 981

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLARMGGSQ 9
           LLA +GGS+
Sbjct: 597 LLAGLGGSE 605
>XP_005247905
          Length = 982

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LLARMGGSQ 9
           LLA +GGS+
Sbjct: 597 LLAGLGGSE 605
>NP_055951
          Length = 2570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LARMGGSQ 9
            LAR+GG +
Sbjct: 1066 LARLGGQE 1073
>XP_006713129
          Length = 1521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LARMGGSQ 9
            LAR+GG +
Sbjct: 1066 LARLGGQE 1073
>XP_006713128
          Length = 1619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LARMGGSQ 9
            LAR+GG +
Sbjct: 1066 LARLGGQE 1073
>XP_005265032
          Length = 2545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LARMGGSQ 9
            LAR+GG +
Sbjct: 1066 LARLGGQE 1073
>XP_005265031
          Length = 2569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LARMGGSQ 9
            LAR+GG +
Sbjct: 1066 LARLGGQE 1073
>XP_005265030
          Length = 2595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LARMGGSQ 9
            LAR+GG +
Sbjct: 1066 LARLGGQE 1073
>NP_001367
          Length = 4646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LLARMGGS 8
            L AR+GGS
Sbjct: 1896 LEARLGGS 1903
>NP_001923
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           R+GGSQ
Sbjct: 350 RLGGSQ 355
>NP_001002264
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>NP_150280
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>NP_059119
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           RMGG+Q
Sbjct: 564 RMGGNQ 569
>NP_001348
          Length = 1270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   ARMGGSQ 9
           ARMGG +
Sbjct: 928 ARMGGEE 934
>NP_942016
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LARMGGSQ 9
           +AR GG+Q
Sbjct: 221 MARTGGTQ 228
>NP_057535
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLARMGGSQ 9
           LLA MG +Q
Sbjct: 693 LLAAMGNTQ 701
>NP_001137534
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLARMGGSQ 9
           LLA MG +Q
Sbjct: 693 LLAAMGNTQ 701
>NP_001137533
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLARMGGSQ 9
           LLA MG +Q
Sbjct: 693 LLAAMGNTQ 701
>XP_006723937
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LARMGGSQ 9
           +AR GG+Q
Sbjct: 221 MARTGGTQ 228
>XP_006723936
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LARMGGSQ 9
           +AR GG+Q
Sbjct: 221 MARTGGTQ 228
>XP_005260286
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LARMGGSQ 9
           +AR GG+Q
Sbjct: 248 MARTGGTQ 255
>XP_006721980
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           R+GGSQ
Sbjct: 148 RLGGSQ 153
>XP_006721978
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           R+GGSQ
Sbjct: 350 RLGGSQ 355
>XP_006719959
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>XP_005266654
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>XP_005266653
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           R+GGSQ
Sbjct: 109 RLGGSQ 114
>XP_005263119
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RMGGSQ 9
           RMGG+Q
Sbjct: 564 RMGGNQ 569
>NP_003186
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LARMGGSQ 9
           +AR GG+Q
Sbjct: 248 MARTGGTQ 255
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.136    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 595,742
Number of extensions: 701
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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