Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1135
NP_001075109                                                           18    1135
NP_588616                                                              17    3301
NP_001137160                                                           17    3301
NP_001116151                                                           17    3301
XP_005254203                                                           17    3301
XP_005254204                                                           17    3301
XP_005254202                                                           17    3301
XP_005254201                                                           17    3301
XP_005266009                                                           17    3301
XP_006714961                                                           17    3301
XP_006714960                                                           17    3301
XP_005266007                                                           17    3301
NP_207646                                                              17    4312
NP_055758                                                              17    4312
NP_945327                                                              17    4312
XP_006720345                                                           17    4312
XP_005268192                                                           17    4312
XP_005268191                                                           17    4312
XP_005250893                                                           17    4312
XP_005250894                                                           17    4312
NP_258441                                                              16    5631
NP_000293                                                              16    7355
NP_002448                                                              16    7355
NP_037361                                                              16    7355
NP_001267717                                                           16    7355
NP_863651                                                              16    7355
NP_001271169                                                           16    7355
NP_001151                                                              16    7355
NP_863658                                                              16    7355
NP_149351                                                              16    7355
NP_001267720                                                           16    7355
NP_001271171                                                           16    7355
NP_001267722                                                           16    7355
NP_001267719                                                           16    7355
NP_001267718                                                           16    7355
XP_005269965                                                           16    7355
XP_006717958                                                           16    7355
XP_006717957                                                           16    7355
XP_006717320                                                           16    7355
NP_001017420                                                           15    9605
NP_001129162                                                           15    9605
NP_006202                                                              15    9605
NP_001136087                                                           15    9605
NP_001136086                                                           15    9605
XP_006716360                                                           15    9605
XP_006715114                                                           15    9605
XP_006715113                                                           15    9605
XP_005264285                                                           15    9605
XP_006712034                                                           15    9605
XP_005264284                                                           15    9605
XP_005264283                                                           15    9605
XP_005264282                                                           15    9605
NP_001136088                                                           15    9605
NP_056067                                                              15    9605
NP_036479                                                              15    9605
>NP_008835
          Length = 4128

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LLAEARSD 8
            LLAEARSD
Sbjct: 2957 LLAEARSD 2964
>NP_001075109
          Length = 4097

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LLAEARSD 8
            LLAEARSD
Sbjct: 2957 LLAEARSD 2964
>NP_588616
          Length = 971

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLAEARSDC 9
          LL +AR DC
Sbjct: 23 LLKDARHDC 31
>NP_001137160
          Length = 1054

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLAEARSDC 9
           LL +AR DC
Sbjct: 106 LLKDARHDC 114
>NP_001116151
          Length = 2765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA A SDC
Sbjct: 1503 LLAGAASDC 1511
>XP_005254203
          Length = 848

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLAEARSDC 9
           LL +AR DC
Sbjct: 106 LLKDARHDC 114
>XP_005254204
          Length = 971

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLAEARSDC 9
          LL +AR DC
Sbjct: 23 LLKDARHDC 31
>XP_005254202
          Length = 971

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLAEARSDC 9
          LL +AR DC
Sbjct: 23 LLKDARHDC 31
>XP_005254201
          Length = 1037

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LLAEARSDC 9
          LL +AR DC
Sbjct: 89 LLKDARHDC 97
>XP_005266009
          Length = 2378

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA A SDC
Sbjct: 1116 LLAGAASDC 1124
>XP_006714961
          Length = 2548

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA A SDC
Sbjct: 1286 LLAGAASDC 1294
>XP_006714960
          Length = 2758

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA A SDC
Sbjct: 1496 LLAGAASDC 1504
>XP_005266007
          Length = 2765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA A SDC
Sbjct: 1503 LLAGAASDC 1511
>NP_207646
          Length = 2572

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA  R+DC
Sbjct: 2140 LLAAQRTDC 2148
>NP_055758
          Length = 837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LAEARSDC 9
           LAE+ SDC
Sbjct: 822 LAESDSDC 829
>NP_945327
          Length = 599

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LAEARSDC 9
           LAEA  DC
Sbjct: 171 LAEAHPDC 178
>XP_006720345
          Length = 1522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA  R+DC
Sbjct: 1090 LLAAQRTDC 1098
>XP_005268192
          Length = 1602

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA  R+DC
Sbjct: 1170 LLAAQRTDC 1178
>XP_005268191
          Length = 2572

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LLAEARSDC 9
            LLA  R+DC
Sbjct: 2140 LLAAQRTDC 2148
>XP_005250893
          Length = 837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LAEARSDC 9
           LAE+ SDC
Sbjct: 822 LAESDSDC 829
>XP_005250894
          Length = 837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LAEARSDC 9
           LAE+ SDC
Sbjct: 822 LAESDSDC 829
>NP_258441
          Length = 437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2 LAEARSDC 9
         +AEA  DC
Sbjct: 1 MAEAEEDC 8
>NP_000293
          Length = 727

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LLAEARSD 8
          LLAEA+ D
Sbjct: 14 LLAEAKGD 21
>NP_002448
          Length = 5179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LLAEARSDC 9
           L AEA +DC
Sbjct: 229 LTAEAFADC 237
>NP_037361
          Length = 1237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LLAEARSDC 9
           LLA   SDC
Sbjct: 704 LLATGSSDC 712
>NP_001267717
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLAEARSD 8
           LLAE+RS+
Sbjct: 115 LLAESRSE 122
>NP_863651
          Length = 1248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LLAEARSDC 9
           LLA   SDC
Sbjct: 715 LLATGSSDC 723
>NP_001271169
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EARSDC 9
           EARS+C
Sbjct: 803 EARSEC 808
>NP_001151
          Length = 1194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LLAEARSDC 9
           LLA   SDC
Sbjct: 704 LLATGSSDC 712
>NP_863658
          Length = 1205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   LLAEARSDC 9
           LLA   SDC
Sbjct: 715 LLATGSSDC 723
>NP_149351
          Length = 269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLAEARSD 8
           LLAE+RS+
Sbjct: 130 LLAESRSE 137
>NP_001267720
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LLAEARSD 8
          LLAE+RS+
Sbjct: 87 LLAESRSE 94
>NP_001271171
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EARSDC 9
           EARS+C
Sbjct: 230 EARSEC 235
>NP_001267722
          Length = 152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LLAEARSD 8
          LLAE+RS+
Sbjct: 13 LLAESRSE 20
>NP_001267719
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LLAEARSD 8
          LLAE+RS+
Sbjct: 87 LLAESRSE 94
>NP_001267718
          Length = 159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLAEARSD 8
           LLAE+RS+
Sbjct: 130 LLAESRSE 137
>XP_005269965
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EARSDC 9
           EARS+C
Sbjct: 230 EARSEC 235
>XP_006717958
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EARSDC 9
           EARS+C
Sbjct: 249 EARSEC 254
>XP_006717957
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EARSDC 9
           EARS+C
Sbjct: 249 EARSEC 254
>XP_006717320
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LLAEARSD 8
           LLAE+RS+
Sbjct: 162 LLAESRSE 169
>NP_001017420
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLAEARSDC 9
           L+ E+RS C
Sbjct: 101 LIKESRSTC 109
>NP_001129162
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLAEARSDC 9
          LLA  R++C
Sbjct: 18 LLATVRAEC 26
>NP_006202
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LLAEARSDC 9
          LLA  R++C
Sbjct: 18 LLATVRAEC 26
>NP_001136087
          Length = 1160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 837 LIAEARS 843
>NP_001136086
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 837 LIAEARS 843
>XP_006716360
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LLAEARSDC 9
           L+ E+RS C
Sbjct: 101 LIKESRSTC 109
>XP_006715114
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3  AEARSDC 9
          AEA  DC
Sbjct: 12 AEAEEDC 18
>XP_006715113
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3  AEARSDC 9
          AEA  DC
Sbjct: 12 AEAEEDC 18
>XP_005264285
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 590 LIAEARS 596
>XP_006712034
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 872 LIAEARS 878
>XP_005264284
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 837 LIAEARS 843
>XP_005264283
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 872 LIAEARS 878
>XP_005264282
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 872 LIAEARS 878
>NP_001136088
          Length = 1160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 837 LIAEARS 843
>NP_056067
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LLAEARS 7
           L+AEARS
Sbjct: 872 LIAEARS 878
>NP_036479
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3  AEARSDC 9
          AEA  DC
Sbjct: 12 AEAEEDC 18
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.130    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 370,973
Number of extensions: 554
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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